ID A0A0N4XL14_NIPBR Unreviewed; 397 AA.
AC A0A0N4XL14;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN ORFNames=NBR_LOCUS3217 {ECO:0000313|EMBL:VDL66806.1};
OS Nippostrongylus brasiliensis (Rat hookworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Heligmosomidae; Nippostrongylus.
OX NCBI_TaxID=27835 {ECO:0000313|Proteomes:UP000038043, ECO:0000313|WBParaSite:NBR_0000321601-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:NBR_0000321601-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDL66806.1, ECO:0000313|Proteomes:UP000271162}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the MCM family. {ECO:0000256|RuleBase:RU004070}.
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DR EMBL; UYSL01004596; VDL66806.1; -; Genomic_DNA.
DR STRING; 27835.A0A0N4XL14; -.
DR WBParaSite; NBR_0000321601-mRNA-1; NBR_0000321601-mRNA-1; NBR_0000321601.
DR OMA; HISEWYA; -.
DR Proteomes; UP000038043; Unplaced.
DR Proteomes; UP000271162; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0032508; P:DNA duplex unwinding; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR031327; MCM.
DR InterPro; IPR018525; MCM_CS.
DR InterPro; IPR001208; MCM_dom.
DR InterPro; IPR041562; MCM_lid.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11630; DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER; 1.
DR PANTHER; PTHR11630:SF26; DNA REPLICATION LICENSING FACTOR MCM7; 1.
DR Pfam; PF00493; MCM; 1.
DR Pfam; PF17855; MCM_lid; 1.
DR PRINTS; PR01657; MCMFAMILY.
DR SMART; SM00350; MCM; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00847; MCM_1; 1.
DR PROSITE; PS50051; MCM_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU004070};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU004070};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022806};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU004070};
KW Reference proteome {ECO:0000313|Proteomes:UP000271162}.
FT DOMAIN 51..212
FT /note="MCM"
FT /evidence="ECO:0000259|PROSITE:PS50051"
SQ SEQUENCE 397 AA; 44124 MW; 3F14ECFD9EFDB155 CRC64;
KSGFRQAGGG LVTETFLEAH YVENIRSNVD DKDAEEDLTE EEVELLAQDN LYDMLAYSIA
PEIYGLTDVK KSLLLTLIGG VDKNASVGLT AAVTKDPVTG EMTLEGGALV LADRGICCID
EFDKMMEADR TSIHEVMEQQ TISIAKAGIM TTLNARVAIV AAANPAFGRY NPRKTIEQNI
DLPAALLSRF DLLWLIQDKP DRDGDRRLAS HITYVHMNAK QPEIDGMKPI DMRIIRRLIE
VAQRKQPVVG DALRERLVEM YVDMRRVSRE SDDSTFTSPR LLLSVIRMST ALARLRLSNV
VLADDIEEAI RLMQASKDSL RPEMQQQEIR QSPVDRAFAI LRELNASSGD AISIQVAIEA
CARKGVSEEA LRDAITVHEG NGVIMIDAQQ RIRFAMN
//
