ID A0A0N4YVQ3_NIPBR Unreviewed; 601 AA.
AC A0A0N4YVQ3;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=Pre-rRNA-processing protein TSR1 homolog {ECO:0000256|ARBA:ARBA00040070};
GN ORFNames=NBR_LOCUS21327 {ECO:0000313|EMBL:VDL85073.1};
OS Nippostrongylus brasiliensis (Rat hookworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Heligmosomidae; Nippostrongylus.
OX NCBI_TaxID=27835 {ECO:0000313|Proteomes:UP000038043, ECO:0000313|WBParaSite:NBR_0002132501-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:NBR_0002132501-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDL85073.1, ECO:0000313|Proteomes:UP000271162}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required during maturation of the 40S ribosomal subunit in
CC the nucleolus. {ECO:0000256|ARBA:ARBA00037087}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604}.
CC -!- SIMILARITY: Belongs to the TRAFAC class translation factor GTPase
CC superfamily. Bms1-like GTPase family. TSR1 subfamily.
CC {ECO:0000256|ARBA:ARBA00038288}.
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DR EMBL; UYSL01026194; VDL85073.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0N4YVQ3; -.
DR STRING; 27835.A0A0N4YVQ3; -.
DR WBParaSite; NBR_0002132501-mRNA-1; NBR_0002132501-mRNA-1; NBR_0002132501.
DR OMA; NTEDIEW; -.
DR Proteomes; UP000038043; Unplaced.
DR Proteomes; UP000271162; Unassembled WGS sequence.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
DR InterPro; IPR012948; AARP2CN.
DR InterPro; IPR039761; Bms1/Tsr1.
DR InterPro; IPR007034; BMS1_TSR1_C.
DR InterPro; IPR030387; G_Bms1/Tsr1_dom.
DR PANTHER; PTHR12858:SF1; PRE-RRNA-PROCESSING PROTEIN TSR1 HOMOLOG; 1.
DR PANTHER; PTHR12858; RIBOSOME BIOGENESIS PROTEIN; 1.
DR Pfam; PF08142; AARP2CN; 1.
DR Pfam; PF04950; RIBIOP_C; 1.
DR SMART; SM00785; AARP2CN; 1.
DR SMART; SM01362; DUF663; 1.
DR PROSITE; PS51714; G_BMS1; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000271162};
KW Ribosome biogenesis {ECO:0000256|ARBA:ARBA00022517}.
FT DOMAIN 31..192
FT /note="Bms1-type G"
FT /evidence="ECO:0000259|PROSITE:PS51714"
FT REGION 1..28
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 295..392
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 306..320
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 335..366
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 367..381
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 601 AA; 67855 MW; 3B3144F686E2249B CRC64;
MSTGHQPGLF KRPAKPHKTF KGKRSKGQID ADNRGTIISC GGSLTPAEFV ESMASCDDTI
VRTLGHNVVY LSVGRFKSRV GLLTPNPAKI DDVLDCIKVS DVVCFLWPTD GELSEENNLL
LTIIKAHGLP SIVNVIPNIA QIPVGKKREE TRKQAVLAIS NASMNDANKV FFCDTELERK
LLVRHFVEMK KSKMLLQKRR PHILVEKLDV ADDNSGICTV LASGYLRGPS WNVNHLIHIQ
GWGDFQLGRI MAHTDPHPLK QNERVQANGD GEPKVLVVAN ESLREPLQSE IVPDPMDAEQ
TWPDEYDVSD DGKVKTEAGV RKVPKGTSSY QAAWIVDDDE EEESDNDEES IDEDEEEGNC
EAGMEMEMVD ESDHEGQNAE ETDDAMSTAI DDDEADDFDE VEKYRRERED AQFPDEIDTP
INDLARIRFQ KYRGLKKQWD QSSPLVLYQL LPHEQRMSVL NMVIRRHPTC RVPIMNKQKL
IFYIGFRKFE ACPVFSQHTN GNKFKMERFL PTDACCVASV YAPITFPPAS VLVFREGKSG
VEKLVATGSL LDVNPDRVVL KRIVLSGHPF KINKRSVVCR YMFFNRGGFP FLICCFNLDW
E
//
