ID   A0A0N4YWC7_NIPBR        Unreviewed;       244 AA.
AC   A0A0N4YWC7;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=Putative sphingolipid delta(4)-desaturase (inferred by orthology to a C. elegans protein) {ECO:0000313|WBParaSite:NBR_0002154901-mRNA-1};
GN   ORFNames=NBR_LOCUS21550 {ECO:0000313|EMBL:VDL85537.1};
OS   Nippostrongylus brasiliensis (Rat hookworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Strongyloidea; Heligmosomidae; Nippostrongylus.
OX   NCBI_TaxID=27835 {ECO:0000313|Proteomes:UP000038043, ECO:0000313|WBParaSite:NBR_0002154901-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:NBR_0002154901-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDL85537.1, ECO:0000313|Proteomes:UP000271162}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; UYSL01026505; VDL85537.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0N4YWC7; -.
DR   STRING; 27835.A0A0N4YWC7; -.
DR   WBParaSite; NBR_0002154901-mRNA-1; NBR_0002154901-mRNA-1; NBR_0002154901.
DR   OMA; MCIPMSI; -.
DR   Proteomes; UP000038043; Unplaced.
DR   Proteomes; UP000271162; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006629; P:lipid metabolic process; IEA:UniProtKB-KW.
DR   InterPro; IPR005804; FA_desaturase_dom.
DR   PANTHER; PTHR12879; SPHINGOLIPID DELTA 4 DESATURASE/C-4 HYDROXYLASE PROTEIN DES2; 1.
DR   PANTHER; PTHR12879:SF8; SPHINGOLIPID DELTA(4)-DESATURASE DES1; 1.
DR   Pfam; PF00487; FA_desaturase; 1.
PE   4: Predicted;
KW   Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000271162};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        16..35
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        42..62
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        82..99
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        119..137
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        157..181
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          41..236
FT                   /note="Fatty acid desaturase"
FT                   /evidence="ECO:0000259|Pfam:PF00487"
SQ   SEQUENCE   244 AA;  28063 MW;  8A88840591C2E207 CRC64;
     MLEKYPQIKD LFGQDPAFKV VVVFMVLAQL VFAWLMRDAD WLLVLLQTYF VSGTFNHALT
     LAVHEISHNQ AYGTARPLAN RLFGFVANLP MCVPMSVSFK KYHIEHHRNL VFCTTARKVL
     WMFLQPLFYG LRPLLIYPKS MTDLELANIV LQLSFDYFIY TYFGVKSFVF LFGGLAIGLG
     LHPLAGHFVS EHYVFNPGQE TYSYYGPINL VTFNVGYHVE HHDFPFVSGA NLPKVRCFPF
     LICK
//