ID A0A0N4ZHQ8_PARTI Unreviewed; 483 AA.
AC A0A0N4ZHQ8;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=PBPe domain-containing protein {ECO:0000313|WBParaSite:PTRK_0000745400.1};
OS Parastrongyloides trichosuri (Possum-specific nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Strongyloididae;
OC Parastrongyloides.
OX NCBI_TaxID=131310 {ECO:0000313|Proteomes:UP000038045, ECO:0000313|WBParaSite:PTRK_0000745400.1};
RN [1] {ECO:0000313|WBParaSite:PTRK_0000745400.1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the glutamate-gated ion channel (TC 1.A.10.1)
CC family. {ECO:0000256|ARBA:ARBA00008685}.
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DR AlphaFoldDB; A0A0N4ZHQ8; -.
DR STRING; 131310.A0A0N4ZHQ8; -.
DR WBParaSite; PTRK_0000745400.1; PTRK_0000745400.1; PTRK_0000745400.
DR Proteomes; UP000038045; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0015276; F:ligand-gated monoatomic ion channel activity; IEA:InterPro.
DR GO; GO:0050906; P:detection of stimulus involved in sensory perception; IEA:UniProt.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 1.
DR InterPro; IPR019594; Glu/Gly-bd.
DR InterPro; IPR001320; Iontro_rcpt_C.
DR PANTHER; PTHR42643; IONOTROPIC RECEPTOR 20A-RELATED; 1.
DR PANTHER; PTHR42643:SF13; IONOTROPIC RECEPTOR 20A-RELATED; 1.
DR Pfam; PF00060; Lig_chan; 1.
DR Pfam; PF10613; Lig_chan-Glu_bd; 1.
DR SMART; SM00918; Lig_chan-Glu_bd; 1.
DR SMART; SM00079; PBPe; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Ligand-gated ion channel {ECO:0000256|ARBA:ARBA00023286};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 190..209
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 221..239
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 254..276
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 452..476
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 60..417
FT /note="Ionotropic glutamate receptor C-terminal"
FT /evidence="ECO:0000259|SMART:SM00079"
FT DOMAIN 72..133
FT /note="Ionotropic glutamate receptor L-glutamate and
FT glycine-binding"
FT /evidence="ECO:0000259|SMART:SM00918"
SQ SEQUENCE 483 AA; 55926 MW; FFC1BAD5DBE5FF10 CRC64;
MSQKNNDTTL ISYDIVVKKL NEIQIILDND DKFVNSYHSK LYGSSDKAYK ISELFGGHLK
VIVPKIEPPY VNYLPLDINH INPIDDPPGV VIMILKTAAE KLNLTYEFII SEEEEWGTLV
NDTWNGSFGK LIYGDYDIIA GGAILRYDRS LYTDMTFPFH YQSYGIMVRS QQNSRSYMWL
IVTDPFSWQV WLYIASSIVL STVIFKILTS ILRNINDEEQ YSLLQSLWIF FSIFLQQALT
RQPKSWTCRI LISMWWMSSI TLLATFTGSL TALFAVNSVI YPFKNFDGMV QSIKASKYTL
LMDINYPSKI EMIAESSLPS YKQLWHEMYV NNKVDFVDGF KSGIEYIKNN PNHVFVAPLE
MLNIYDGLEC NMLILSDEIL SSYLSIPFKK GSKYSDYFSD QIREYMEHGF IDKWISDYKT
QIYSENTKRC NTSNKQTSND VSLGIDKAKG SLYVYLFGVC ISIIVIIFEI ITHYSILLLR
KFK
//
