ID   A0A0N4ZKE5_PARTI        Unreviewed;       812 AA.
AC   A0A0N4ZKE5;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 37.
DE   SubName: Full=Protein kinase domain-containing protein {ECO:0000313|WBParaSite:PTRK_0000857800.1};
OS   Parastrongyloides trichosuri (Possum-specific nematode worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Strongyloididae;
OC   Parastrongyloides.
OX   NCBI_TaxID=131310 {ECO:0000313|Proteomes:UP000038045, ECO:0000313|WBParaSite:PTRK_0000857800.1};
RN   [1] {ECO:0000313|WBParaSite:PTRK_0000857800.1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
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DR   AlphaFoldDB; A0A0N4ZKE5; -.
DR   STRING; 131310.A0A0N4ZKE5; -.
DR   WBParaSite; PTRK_0000857800.1; PTRK_0000857800.1; PTRK_0000857800.
DR   Proteomes; UP000038045; Unplaced.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR   CDD; cd06183; cyt_b5_reduct_like; 1.
DR   Gene3D; 3.10.120.10; Cytochrome b5-like heme/steroid binding domain; 1.
DR   Gene3D; 3.40.50.80; Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module; 1.
DR   Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR   Gene3D; 2.40.30.10; Translation factors; 1.
DR   InterPro; IPR008333; Cbr1-like_FAD-bd_dom.
DR   InterPro; IPR001199; Cyt_B5-like_heme/steroid-bd.
DR   InterPro; IPR036400; Cyt_B5-like_heme/steroid_sf.
DR   InterPro; IPR018506; Cyt_B5_heme-BS.
DR   InterPro; IPR017927; FAD-bd_FR_type.
DR   InterPro; IPR039261; FNR_nucleotide-bd.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   InterPro; IPR000719; Prot_kinase_dom.
DR   InterPro; IPR017938; Riboflavin_synthase-like_b-brl.
DR   InterPro; IPR008271; Ser/Thr_kinase_AS.
DR   PANTHER; PTHR11909; CASEIN KINASE-RELATED; 1.
DR   PANTHER; PTHR11909:SF300; TAU-TUBULIN KINASE HOMOLOG ASATOR; 1.
DR   Pfam; PF00173; Cyt-b5; 1.
DR   Pfam; PF00970; FAD_binding_6; 1.
DR   Pfam; PF00069; Pkinase; 1.
DR   PRINTS; PR00406; CYTB5RDTASE.
DR   PRINTS; PR00363; CYTOCHROMEB5.
DR   SMART; SM01117; Cyt-b5; 1.
DR   SMART; SM00220; S_TKc; 1.
DR   SUPFAM; SSF55856; Cytochrome b5-like heme/steroid binding domain; 1.
DR   SUPFAM; SSF52343; Ferredoxin reductase-like, C-terminal NADP-linked domain; 1.
DR   SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR   SUPFAM; SSF63380; Riboflavin synthase domain-like; 1.
DR   PROSITE; PS00191; CYTOCHROME_B5_1; 1.
DR   PROSITE; PS50255; CYTOCHROME_B5_2; 1.
DR   PROSITE; PS51384; FAD_FR; 1.
DR   PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR   PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE   4: Predicted;
KW   Heme {ECO:0000256|ARBA:ARBA00022617}; Iron {ECO:0000256|ARBA:ARBA00023004};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723}.
FT   DOMAIN          42..334
FT                   /note="Protein kinase"
FT                   /evidence="ECO:0000259|PROSITE:PS50011"
FT   DOMAIN          373..449
FT                   /note="Cytochrome b5 heme-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS50255"
FT   DOMAIN          577..677
FT                   /note="FAD-binding FR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51384"
SQ   SEQUENCE   812 AA;  93530 MW;  5089EE04B026AE36 CRC64;
     MANNLKLRSA TYFQCHTSTA AYNLKKKKKV LIRSNTKIYD RYVIEKVVNG GNYGQIYTAI
     DEKANKKSLI LKVVHENYEP ELLIMERNIL MKLRGKPNIP MILASGTYKE YVYIGLERLG
     KNMTEIRCMQ KEKFLSPLTV TKVAIQALSA LEVLHNSGYL HRDVKPENLV IGSNPNSIST
     IYLIDFGMAR RYLDGNGKIR RARKTVGFRG SMRYVSIELH KRFEHTPQND IWSLFYSCIE
     LGESELPWTS LINEDEIMTK KIHLKPHDLC IKMPKGFGDF GSSIGNAPYF EAVNYNKLFK
     ALNSIFTKSE METHIFEWTK RSSLYTALKS RSFFKKGDRT TADGRNKVAL KPGRSLNDWI
     QKHSKQKNLR SESNIVTLEE LSQHNKPNDC WIILNGKVYD VTEYLEYHPG GVSEITNYAG
     MDATEAFIDI HSWVNYNGFL KNYCMGTFKG KLPKVSKMKS IDEDEDYEEN QSMKLIEERK
     FQFKKHSMKS FEITSPFWKT LRSQCLSHYI IDDTLHIRAR DFRDDVYSFT YHPASKLYDS
     MLNVQCENDK IIINSDIPLP ILAFNERKWR VSKNPSTNYV KGKLLKKEKI THDTFYVSIQ
     LLDGAIIGIP EGHHVALRLL VRNNKLSRPY TPIRVNESKI EFLIKIYDDG LLTPTIGSLQ
     EGDTLEVSDT IGKLDFINGT KNNANCLCLA AGTGLTPMLR IIEDRVKKGI HTKLFLFNKK
     YDDIISEKYF PLEDSNFSLT NILSQEEEIK MMNNDLMSNI LLGYIRKEIF DTIPDINKYQ
     VFICGPWKFS SLAEEILQSL GLANSNIHVF DG
//