ID   A0A0N4ZV04_PARTI        Unreviewed;       697 AA.
AC   A0A0N4ZV04;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 37.
DE   SubName: Full=Protein kinase domain-containing protein {ECO:0000313|WBParaSite:PTRK_0001241500.1};
OS   Parastrongyloides trichosuri (Possum-specific nematode worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Strongyloididae;
OC   Parastrongyloides.
OX   NCBI_TaxID=131310 {ECO:0000313|Proteomes:UP000038045, ECO:0000313|WBParaSite:PTRK_0001241500.1};
RN   [1] {ECO:0000313|WBParaSite:PTRK_0001241500.1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
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DR   AlphaFoldDB; A0A0N4ZV04; -.
DR   STRING; 131310.A0A0N4ZV04; -.
DR   WBParaSite; PTRK_0001241500.1; PTRK_0001241500.1; PTRK_0001241500.
DR   Proteomes; UP000038045; Unplaced.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; IEA:UniProt.
DR   Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR   InterPro; IPR046349; C1-like_sf.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   InterPro; IPR002219; PE/DAG-bd.
DR   InterPro; IPR000719; Prot_kinase_dom.
DR   InterPro; IPR017441; Protein_kinase_ATP_BS.
DR   InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
DR   InterPro; IPR008266; Tyr_kinase_AS.
DR   PANTHER; PTHR23257:SF780; AT08303P; 1.
DR   PANTHER; PTHR23257; SERINE-THREONINE PROTEIN KINASE; 1.
DR   Pfam; PF07714; PK_Tyr_Ser-Thr; 1.
DR   SMART; SM00109; C1; 1.
DR   SUPFAM; SSF57889; Cysteine-rich domain; 1.
DR   SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR   PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR   PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR   PROSITE; PS00109; PROTEIN_KINASE_TYR; 1.
DR   PROSITE; PS50081; ZF_DAG_PE_2; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|PROSITE-ProRule:PRU10141};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU10141};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT   DOMAIN          111..162
FT                   /note="Phorbol-ester/DAG-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50081"
FT   DOMAIN          410..687
FT                   /note="Protein kinase"
FT                   /evidence="ECO:0000259|PROSITE:PS50011"
FT   REGION          42..105
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          188..245
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          281..300
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        42..73
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        85..105
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        189..245
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         436
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ   SEQUENCE   697 AA;  78484 MW;  F684FC082109980E CRC64;
     MTINNPRFSN NELLKTYQDA SKKGAYLRNT SSLHAIAETI ETANQSSDTT SSLTVSNPSK
     TLPISRSTHF QFPNPPPDSI PNRPSPFSPI SKTTNAKPSQ GTFNSTPHSI PHVWVSKRLP
     TICSDICIGC NKTLGFVSFW EKCKSCKKKV HSDCKKRIGN TCGLTPEFFK AVFKELYMAR
     GQEIWDPYRT SGGESSSSTN STAPSTPAPN LIHSVITKQE QGSSSMTSSI NTTSEHFTFS
     ESNNTASHSQ IFPRSQMVDS NTKNNNCYDV PSIILTDTNV LSESPNKTGP SASDSSICTT
     SSNNESFLTT DQVNTLVKKE VPVITTTSTT LTGTNGTNDS DKTLKNVTFE DVSGLDGLNF
     GGDENSDRQG IYYRLNFKTA SMREKNQKKG KKKYENIPED SETNINHCAI EVLELIGYGR
     FGEVRRGHYF GDVAIKLLNM DHVPEAKQYE TFLMDTDSFV KARHENIILF LGYTYEKGNL
     GIVMNDCKGK TLYQLIHESL PNESLEFSQI INFSLQICQG MTYLHTKGIL HKDLRTKNIF
     IEKNNRIVIT DFGIFNMARL RHPPRKNGFY VSENWLCYLA PELIRAITPS AKPLRFTEKS
     DVYSFGTCCF EMFFGKFPFS GYSWEVKMFF IEQGMKAPFC GNEVSREMKN ILMNCWSYNP
     RNRPAFEDIF GNFGKLPKKK VMRSPSFPIQ RSYESFF
//