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Database: UniProt
Entry: A0A0N5AD15_9BILA
LinkDB: A0A0N5AD15_9BILA
Original site: A0A0N5AD15_9BILA 
ID   A0A0N5AD15_9BILA        Unreviewed;       882 AA.
AC   A0A0N5AD15;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   12-APR-2017, entry version 5.
DE   RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189};
OS   Syphacia muris.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Oxyurida;
OC   Oxyuroidea; Oxyuridae; Syphacia.
OX   NCBI_TaxID=451379 {ECO:0000313|Proteomes:UP000046393, ECO:0000313|WBParaSite:SMUV_0000204601-mRNA-1};
RN   [1] {ECO:0000313|Proteomes:UP000046393, ECO:0000313|WBParaSite:SMUV_0000204601-mRNA-1}
RP   NUCLEOTIDE SEQUENCE.
RG   Helminth Genomes Consortium;
RL   Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|WBParaSite:SMUV_0000204601-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
CC   -!- FUNCTION: Essential component of the vacuolar proton pump (V-
CC       ATPase), a multimeric enzyme that catalyzes the translocation of
CC       protons across the membranes. Required for assembly and activity
CC       of the V-ATPase. {ECO:0000256|RuleBase:RU361189}.
CC   -!- SIMILARITY: Belongs to the V-ATPase 116 kDa subunit family.
CC       {ECO:0000256|RuleBase:RU361189}.
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DR   WBParaSite; SMUV_0000204601-mRNA-1; SMUV_0000204601-mRNA-1; SMUV_0000204601.
DR   Proteomes; UP000046393; Genome Assembly.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0000220; C:vacuolar proton-transporting V-type ATPase, V0 domain; IEA:InterPro.
DR   GO; GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
DR   InterPro; IPR002490; V-ATPase_116kDa_su.
DR   InterPro; IPR026028; V-type_ATPase_116kDa_su_euka.
DR   PANTHER; PTHR11629; PTHR11629; 1.
DR   Pfam; PF01496; V_ATPase_I; 1.
DR   PIRSF; PIRSF001293; ATP6V0A1; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000046393};
KW   Hydrogen ion transport {ECO:0000256|RuleBase:RU361189};
KW   Ion transport {ECO:0000256|RuleBase:RU361189};
KW   Membrane {ECO:0000256|RuleBase:RU361189};
KW   Reference proteome {ECO:0000313|Proteomes:UP000046393};
KW   Transmembrane {ECO:0000256|RuleBase:RU361189};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU361189};
KW   Transport {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    421    445       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    465    484       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    559    576       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    588    612       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    624    647       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    677    696       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    810    834       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   COILED       94    128       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   882 AA;  100863 MW;  CCBD566286FABA32 CRC64;
     MGSLYRSEEM CLAQLFLQTE AAYTCVAELG ELGLVQFRDL NPGVSAFQRK FVNEVRRCDE
     MERKLRFLEH EFRKDGIVML DTGESPDAPP PREMIDLEAT FEKLENELRE VNQNEEMLKK
     NYLELTELKH ILQKTQQFFD EAGQDASLPT NMSSSSAGGL PEQIVLQETE GMGIELSGVP
     AGAMFANFGF VAGVIQRERL PGFERLLWRA CRGNAFLRQS EINEPLIDSA GVMVKKTVFI
     IFFQGDQLKT RVKKICEGFR ATLYPCPDTP MERREMSIGV MTRIEDLKTV LHQTQDHRHR
     VLVAASKNVR MWLTKVRKIK SIYHTLNLFN LDVTQKCLIA ECWCPVADLD RIQLALKRGT
     EESGSTVPSI LNRMVDSTEL PPTYHRVNKF TRAFQNIVDS YGIASYREIN PAPYTMITFP
     FLFAIMFGDC GHGLIMLIAA LWFIYKEKQI EAARVSDEIF NTFFGGRYLI LLMGCFSVYT
     GFIYNDMFSK SFNLFGSGWR NPYNLDKMKQ SAPETEFILY PEYAFYNVSS GPYLIGVDPI
     WNLADNNKLS FLNSMKMKLS VIIGVAHMTF GVVLSYENYK YFNSRLDFLF MFIPQMLFLG
     CIFIYLCLEV IIKWMAFSAK PGYVLGYYYP GSNCAPSLLI GLINMFMMKS RPTGFVKADG
     TTYMQCYLNY WYPGQQFFEF LFLMVAICCI PVMLFAKPYF LWKEHKNYRA IGSTLVGSVQ
     ADVSSDDVQV LQNNDDSNVS KSQGDEGPVS GFDITDTMVY QAIHTIEFVL GCVSHTASYL
     RLWALSLAHA QLSEVLWNMV FRQSFFVSGY LGALATYILF FIFAFLSFSI LVLMEGLSAF
     LHALRLHWVE FQSKFYKGLG YPFLPFSFDT ILEEARAAEE TL
//
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