ID   A0A0N5ANZ2_9BILA        Unreviewed;       939 AA.
AC   A0A0N5ANZ2;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 36.
DE   SubName: Full=G_PROTEIN_RECEP_F3_4 domain-containing protein {ECO:0000313|WBParaSite:SMUV_0000634701-mRNA-1};
OS   Syphacia muris.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Oxyuridomorpha; Oxyuroidea; Oxyuridae; Syphacia.
OX   NCBI_TaxID=451379 {ECO:0000313|Proteomes:UP000046393, ECO:0000313|WBParaSite:SMUV_0000634701-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:SMUV_0000634701-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the G-protein coupled receptor 3 family.
CC       {ECO:0000256|ARBA:ARBA00007242}.
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DR   AlphaFoldDB; A0A0N5ANZ2; -.
DR   STRING; 451379.A0A0N5ANZ2; -.
DR   WBParaSite; SMUV_0000634701-mRNA-1; SMUV_0000634701-mRNA-1; SMUV_0000634701.
DR   Proteomes; UP000046393; Unplaced.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004930; F:G protein-coupled receptor activity; IEA:InterPro.
DR   CDD; cd15285; 7tmC_mGluR_group1; 1.
DR   Gene3D; 3.40.50.2300; -; 2.
DR   Gene3D; 2.10.50.30; GPCR, family 3, nine cysteines domain; 1.
DR   InterPro; IPR001828; ANF_lig-bd_rcpt.
DR   InterPro; IPR000337; GPCR_3.
DR   InterPro; IPR011500; GPCR_3_9-Cys_dom.
DR   InterPro; IPR038550; GPCR_3_9-Cys_sf.
DR   InterPro; IPR017978; GPCR_3_C.
DR   InterPro; IPR000162; GPCR_3_mtglu_rcpt.
DR   InterPro; IPR028082; Peripla_BP_I.
DR   PANTHER; PTHR24060:SF134; G_PROTEIN_RECEP_F3_4 DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR24060; METABOTROPIC GLUTAMATE RECEPTOR; 1.
DR   Pfam; PF00003; 7tm_3; 1.
DR   Pfam; PF01094; ANF_receptor; 1.
DR   Pfam; PF07562; NCD3G; 1.
DR   PRINTS; PR00248; GPCRMGR.
DR   PRINTS; PR00593; MTABOTROPICR.
DR   SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR   PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        543..565
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        577..597
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        609..626
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        647..673
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        688..718
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        730..749
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          545..771
FT                   /note="G-protein coupled receptors family 3 profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50259"
FT   REGION          784..803
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   939 AA;  105723 MW;  05CCD55448FF0AA3 CRC64;
     MIGALFPEHQ QRKEGCGTIW EQYGIQRTEI ALKTVRDLNY VLPFKLGITI RDSCWTERVA
     MEQAIAFLRG GVAQRPCCTT SGCDEETNAI VAVVGPAKSS TTIAVQNLLQ VFRIPQIGYG
     ATTPDLSDKE QYSYFMRVVP SDAWQSRAII AILEKYKWRY VAVVYSAGNY GEKGFEEIQK
     SIKDTDICIA FQHKVKSLAN TEEFDRIINS IREVPGKLQV IICFCEGRTI HNMFRAQQRL
     RQNDSSIKSY QWIGSDGWAD RPDVVKGVED EAAGSFSIRI HSPYVDEFDD YYRSLNPTNN
     VDNPWFAEFW EENYHCRLTV PTAKIKEPAN NVTGVCNSNL NITDYIQDAK LSQVANSIRV
     IAFALRNMFY DRCPDNKTLC EDMKNINGTI LYKYMLNVTF TDQFGQEMYF DTNGDPPAWY
     DVLNYVGLQN GFQTVGEYRK KRRSGYKLEI TKDVIFSEVT YYDGATKIPR SVCSDECTAG
     QKKSTTHGCC WTCDNCTDTQ IVNRTINECQ VCPPGTWPND EKTECYQLNG EALYWLEAKV
     ICAWILALAG VIATLLTTAV FVRYNHTPMV KSTTRELSYI ILSGIMACYA VTFIILAHPT
     FISCFLTRIV PPIAFSIIYS ALLTKTNRIA RILAGSKKRI LTKKPRFLST SAQVVITWLL
     VGVECVIVAV GVMEEMPQVG YIYKPRRMFV ICSSSTAAFL SPFLWNLFLI TLCTLYAIKT
     RNLPENFNEA KFIGFTIISA TVALSLLFFP KLYIILFHPE KNVRASYTTT KLIRCHFGNS
     QATDSKHISF SKTGTSQHSG SSLTYPVRTA SVRLSQASSQ DASTQTNSIS SPSRFGRSFS
     ILRHRRSTKP LDNEIIDLIE CCRRYQEAKA QSSTSNFLIE ETHDDEVRNL LAGSIEQSVK
     AALSAVARPP GDPGSSKDFE DLLKSRGLTA VDLSKPTNL
//