ID A0A0N5B0G6_9BILA Unreviewed; 2144 AA.
AC A0A0N5B0G6;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=Myosin motor domain-containing protein {ECO:0000313|WBParaSite:SMUV_0001076801-mRNA-1};
OS Syphacia muris.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Oxyuridomorpha; Oxyuroidea; Oxyuridae; Syphacia.
OX NCBI_TaxID=451379 {ECO:0000313|Proteomes:UP000046393, ECO:0000313|WBParaSite:SMUV_0001076801-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:SMUV_0001076801-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|ARBA:ARBA00008314,
CC ECO:0000256|PROSITE-ProRule:PRU00782}.
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DR STRING; 451379.A0A0N5B0G6; -.
DR WBParaSite; SMUV_0001076801-mRNA-1; SMUV_0001076801-mRNA-1; SMUV_0001076801.
DR Proteomes; UP000046393; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:UniProtKB-UniRule.
DR CDD; cd17092; FERM1_F1_Myosin-VII; 1.
DR CDD; cd17093; FERM2_F1_Myosin-VII; 1.
DR CDD; cd14473; FERM_B-lobe; 2.
DR CDD; cd13198; FERM_C1_MyoVII; 1.
DR CDD; cd13199; FERM_C2_MyoVII; 1.
DR CDD; cd01381; MYSc_Myo7; 1.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.5.190; -; 1.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 1.20.80.10; -; 2.
DR Gene3D; 6.20.240.20; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR Gene3D; 1.25.40.530; MyTH4 domain; 2.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 2.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR019749; Band_41_domain.
DR InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR InterPro; IPR035963; FERM_2.
DR InterPro; IPR019748; FERM_central.
DR InterPro; IPR000299; FERM_domain.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR041793; MyoVII_FERM_C1.
DR InterPro; IPR041794; MyoVII_FERM_C2.
DR InterPro; IPR036106; MYSc_Myo7.
DR InterPro; IPR000857; MyTH4_dom.
DR InterPro; IPR038185; MyTH4_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR22692:SF33; MYOSIN; 1.
DR PANTHER; PTHR22692; MYOSIN VII, XV; 1.
DR Pfam; PF00373; FERM_M; 1.
DR Pfam; PF00612; IQ; 2.
DR Pfam; PF00063; Myosin_head; 1.
DR Pfam; PF00784; MyTH4; 2.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM00295; B41; 2.
DR SMART; SM00015; IQ; 3.
DR SMART; SM00242; MYSc; 1.
DR SMART; SM00139; MyTH4; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF47031; Second domain of FERM; 2.
DR SUPFAM; SSF54236; Ubiquitin-like; 2.
DR PROSITE; PS50057; FERM_3; 2.
DR PROSITE; PS50096; IQ; 3.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
DR PROSITE; PS51016; MYTH4; 2.
DR PROSITE; PS50002; SH3; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Repeat {ECO:0000256|ARBA:ARBA00022737};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 63..751
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT DOMAIN 967..1215
FT /note="MyTH4"
FT /evidence="ECO:0000259|PROSITE:PS51016"
FT DOMAIN 1220..1536
FT /note="FERM"
FT /evidence="ECO:0000259|PROSITE:PS50057"
FT DOMAIN 1531..1599
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 1671..1819
FT /note="MyTH4"
FT /evidence="ECO:0000259|PROSITE:PS51016"
FT DOMAIN 1825..2129
FT /note="FERM"
FT /evidence="ECO:0000259|PROSITE:PS50057"
FT REGION 629..651
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT BINDING 156..163
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
SQ SEQUENCE 2144 AA; 246211 MW; 5BAAC4850D53E03F CRC64;
MVIVTKGDFI WIEPTSKTLF SCPIGARVVD ADGGRIKVID DQGREQWLTS ERRIRLMHPT
SIQGVEDMIQ LGDLHESGIL RNLFVRYSEK LIYTYTGSIL IAVNPYLDLP IYAAEQIRMY
RNRRIGEMPP HIFAISDNAY NNMKRTGNNQ CIIISGESGA GKTESTKLVL QFLATISGQH
SWIEQQVLEA NPIMEAFGNA KTVRNDNSSR FGKYIDIHFR GDGAIEGAKV EQYLLEKSRI
VNQAHNERNY HIFYCLLAGL SQAEKDKLYL KDAKDYYYLT QGKTLIADGR DDAADLAEIR
SAMKVLFFKD LEIWAVFNIL AALLHIGNIK YNATILNNME ATEIRDKVGV ARVAKLLQVS
RFLLDQIHTQ VDERSLVNAL TTRSLVTREE RVVSCLTAEQ SLDVRDALVK GIYGRLFIAI
VKKINDAIYR PKKSGKIRYS IGVLDIFGFE NFAVNSFEQL CINYANENLQ QFFVRHVFRL
EQREYEMEKI NWKNIEYTDN QDVLDLVAMK PMNIFSIIDE ESIFPKGTDQ TMLNKLHANH
SNASRLYLRP KSDLNKSFGV VHYAGPVFYS SKGFLEKNRD SFSSDLYSLV HNSEMKFLVN
LFETENDCET VTTTRRKQAT VSGQFRRSLE ALMAQIALCE PFFIRCIKPN EYKRALMFDR
ELVCKQLRYS GMMETIKIRK AGYPIRYDYP YFVARYRILV DGIGPPQKVD CRQASKTICD
RVLGPNADYQ LGNSKVFLKD AQQLSLEQEH DRMLHTRAVL IQKTLRGWLQ RKKFNCMRNA
AIMIQKHYRG YAQRKRYMQA NLQKLLMQVG FARLQAVLRT RHLVIYYRHL KAIVIQFQAL
CRGAMVRKAI KAKRERGERH AGLVIKTEEP ARESSPVPAV NDELDDSRWV EEMFGFLPES
GLENIEPLPP ITNPKFLGLH KSSAISPVPS PVETPPPTED HSTEDLSGFQ FGKFAATYFQ
GQATAEHIKK PLRASLLLHE DPGNQLAAMA VWITILRFMG DLPEPKYYPS VNNKTSVMGK
LYETLGRKFT VDDVLMASKN SEYEQMSRQK IKKSSTVTRK LIQMTLKKKS KISGMKQKGD
REARAIIEAM DSGSKQFNAL LDDRPTSNLD KLHYIIGHGI LRSELREEIY CQICKQLTNN
PSRSSNARGW ILLSLCVGCF APPQRFINYL YHFIRENGPK GSVNYSSYIE QRLRRTVANG
TRHQPPSYIE LQATKSKKAI VLSITLMDES VKSLNADSAT TAKELCEALS QKIGLKDRFG
FSLYIALFDK VSSLGAGTDH VMDAVSQCEQ YAKEQGRLER NAPWRLFFRK EIFSPWDDAR
FDPISTDLIY HQVVRGVKYG EYRTDKDEDL AVLIAEQMFI NSGPRIDVND IDKLEESLQR
YLPDYELKSA NSEMLQKWLQ LVMHAYRKKF NQNEVTKEQV KSAVVKFAKY KWPLLFSRFY
EAFKFAGPPL AKNEVIIAVN WTGIYAVDDQ EQVLLEFSFP EVNRILCMAP SRTGIESFTI
ETIGKDEYTF QSPNTEDIKE LVDYFLQGLS SRSRYLVALQ ENRGDEAANY LEFKRGDLLL
LPDGITGDTV RKNQFVKGEN ARTGKRGNIP VELVRILPTL EKPTIEILET FAKQPEFDSQ
INRQVSLMNV PNSDLPYTLE RFAADNFRPP QRRTLTLTSR RSDKNNNLWM HSRDVLKAPL
LKKLIGKDEP SHEAVSMFLA ILKYMGDHPF RKPRTGTELT DQIFRGPLRY EILRDELYCQ
IMKQLTANCN PISEERGWEL LWLCIGLFPP SQPLLKEVLQ FLRSREHPVA ADCYNRLQKT
LRSGRRKFPP HQVEVEAIQH KTTQIFHKAF FPDGSEEAIE VESSTRARDF CQRIATRLRL
KSSAGFSLFV KLDQKVISVP ESEFFFDFVR QISDWAHQVH VAEGGLPHFS YQVHFMKKLW
INTIPGEDPA ADLVFHYPQE LPKYLKGYHK VSKQQAIELA ALIFRAGIQR DKYSFFTQLP
QRLHDFVPED LLQAYSRNEW KKLIAAAYAG EIETMSAEEA KITFLKRVAQ WPTFGSAFFE
VKQSSDPTLP DVLLIAINKT GVNLYNLNTK ELISNYPFTS ISNWTSGTTY FHMTIGNLTK
GNRLLLETSL GYKMDDLLTS YIRMFLSSST NNRDEMNFTE NDVI
//
