ID   A0A0N5B3E9_STREA        Unreviewed;       328 AA.
AC   A0A0N5B3E9;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=TGF_BETA_2 domain-containing protein {ECO:0000313|WBParaSite:SPAL_0000060000.1};
OS   Strongyloides papillosus (Intestinal threadworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Strongyloididae;
OC   Strongyloides.
OX   NCBI_TaxID=174720 {ECO:0000313|Proteomes:UP000046392, ECO:0000313|WBParaSite:SPAL_0000060000.1};
RN   [1] {ECO:0000313|WBParaSite:SPAL_0000060000.1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the TGF-beta family.
CC       {ECO:0000256|ARBA:ARBA00006656, ECO:0000256|RuleBase:RU000354}.
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DR   AlphaFoldDB; A0A0N5B3E9; -.
DR   STRING; 174720.A0A0N5B3E9; -.
DR   WBParaSite; SPAL_0000060000.1; SPAL_0000060000.1; SPAL_0000060000.
DR   Proteomes; UP000046392; Unplaced.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
DR   CDD; cd19378; TGF_beta_DAF7; 1.
DR   Gene3D; 2.10.90.10; Cystine-knot cytokines; 1.
DR   InterPro; IPR029034; Cystine-knot_cytokine.
DR   InterPro; IPR001839; TGF-b_C.
DR   InterPro; IPR015615; TGF-beta-rel.
DR   InterPro; IPR017948; TGFb_CS.
DR   PANTHER; PTHR11848:SF292; INHIBIN BETA CHAIN; 1.
DR   PANTHER; PTHR11848; TGF-BETA FAMILY; 1.
DR   Pfam; PF00019; TGF_beta; 1.
DR   SMART; SM00204; TGFB; 1.
DR   SUPFAM; SSF57501; Cystine-knot cytokines; 1.
DR   PROSITE; PS00250; TGF_BETA_1; 1.
DR   PROSITE; PS51362; TGF_BETA_2; 1.
PE   3: Inferred from homology;
KW   Growth factor {ECO:0000256|ARBA:ARBA00023030,
KW   ECO:0000256|RuleBase:RU000354}; Secreted {ECO:0000256|ARBA:ARBA00022525};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           20..328
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5005893660"
FT   DOMAIN          215..328
FT                   /note="TGF-beta family profile"
FT                   /evidence="ECO:0000259|PROSITE:PS51362"
SQ   SEQUENCE   328 AA;  37988 MW;  EA3241000A4314F2 CRC64;
     MKYYYIIAII FFSFCQTLAS NGRWYNDLER NRILQNILTS FGLKKPIFLD IPTENLVGIT
     RNIENVVEDK ENENKIKKYL QIEPISYNHP IAIFRSDDLI KNSISIKALS LKIDYTVVGD
     LEEPLKANVL LLLNKNNDEN EHLGNFIFDS HKNGNLNEKM YTLKMPLNLT VFKNYIPEIG
     DMIKFLIKFN EIPKPIIINI ENVYLEAVVI DNNDRVKRNS DKNCENEDGR SMCCVKKTNI
     NFEEIGWNFI VSPKNFQAQF CHGDCYHSGN NMLIGGVLNK LKHLQDIKYK SCCYPIEYIP
     LNVSIFKSGL TVETRTLNNL IAKKCTCY
//