ID A0A0N5B774_STREA Unreviewed; 510 AA.
AC A0A0N5B774;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=Histone-lysine N-methyltransferase {ECO:0000313|WBParaSite:SPAL_0000190100.1};
OS Strongyloides papillosus (Intestinal threadworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Strongyloididae;
OC Strongyloides.
OX NCBI_TaxID=174720 {ECO:0000313|Proteomes:UP000046392, ECO:0000313|WBParaSite:SPAL_0000190100.1};
RN [1] {ECO:0000313|WBParaSite:SPAL_0000190100.1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Chromosome, centromere
CC {ECO:0000256|ARBA:ARBA00004584}. Nucleus
CC {ECO:0000256|ARBA:ARBA00004123}.
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DR AlphaFoldDB; A0A0N5B774; -.
DR STRING; 174720.A0A0N5B774; -.
DR WBParaSite; SPAL_0000190100.1; SPAL_0000190100.1; SPAL_0000190100.
DR Proteomes; UP000046392; Unplaced.
DR GO; GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:0046974; F:histone H3K9 methyltransferase activity; IEA:UniProt.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd00024; CD_CSD; 1.
DR Gene3D; 2.40.50.40; -; 1.
DR Gene3D; 2.170.270.10; SET domain; 1.
DR InterPro; IPR016197; Chromo-like_dom_sf.
DR InterPro; IPR000953; Chromo/chromo_shadow_dom.
DR InterPro; IPR023780; Chromo_domain.
DR InterPro; IPR003616; Post-SET_dom.
DR InterPro; IPR007728; Pre-SET_dom.
DR InterPro; IPR001214; SET_dom.
DR InterPro; IPR046341; SET_dom_sf.
DR PANTHER; PTHR45660; HISTONE-LYSINE N-METHYLTRANSFERASE SETMAR; 1.
DR PANTHER; PTHR45660:SF13; HISTONE-LYSINE N-METHYLTRANSFERASE SETMAR; 1.
DR Pfam; PF00385; Chromo; 1.
DR Pfam; PF05033; Pre-SET; 1.
DR Pfam; PF00856; SET; 1.
DR SMART; SM00298; CHROMO; 1.
DR SMART; SM00508; PostSET; 1.
DR SMART; SM00317; SET; 1.
DR SUPFAM; SSF54160; Chromo domain-like; 1.
DR SUPFAM; SSF82199; SET domain; 1.
DR PROSITE; PS50013; CHROMO_2; 1.
DR PROSITE; PS50868; POST_SET; 1.
DR PROSITE; PS50280; SET; 1.
PE 4: Predicted;
KW Centromere {ECO:0000256|ARBA:ARBA00023328};
KW Chromosome {ECO:0000256|ARBA:ARBA00022454};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 64..107
FT /note="Chromo"
FT /evidence="ECO:0000259|PROSITE:PS50013"
FT DOMAIN 259..383
FT /note="SET"
FT /evidence="ECO:0000259|PROSITE:PS50280"
FT DOMAIN 395..411
FT /note="Post-SET"
FT /evidence="ECO:0000259|PROSITE:PS50868"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 41..60
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 464..510
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..20
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 41..57
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 474..501
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 510 AA; 59074 MW; 40472D7C4F3EC442 CRC64;
MSDFKSNEKM KHKKYRTDGY KTPSKSLISI SKHKKKFENS FYKKSKGVQK RETSDSDDNS
QGNFSVEMIL AYNPETKLYL VKWEKYCWSA VTWEPYENIK ECREFLEYNR DRDKVLTRLR
TTEYFRDLKP FLYPKNEDQY VNIFGAFSVE LAIRSCDEDL PPIYVVNWVD HEIPPEFSYV
PSIIIKPKFA EDININSQVE PCTNCVAEKE TDYCEQYKEH FLKNHINFNV KEVRMSCTEK
CNCARTPCPT RVADSGRVRK LIIAKTIDKG WGLFAGDNIK AGEFICEYAG ELISRNQAVS
RKNDYIFDMD YMCGHESDHS GNAKFAIDAY KYGNEGRFAN HSCNPNARAI SIYSQFKCED
YHKIGFFAKQ NIQFGDEITI DYFGAEVENN TDRFSMVPCN CGAENCRKYI PIMNSLTKKK
VNGSRDDTPE AEQVTLNKLG IVEYNEMFAP EKFYRSQKLS KLLKRDRGDS VSTKDKSNTS
SSDKSSERSS SHNSDNVKGQ INIMNILKHK
//
