ID A0A0N5C100_STREA Unreviewed; 642 AA.
AC A0A0N5C100;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=TPT domain-containing protein {ECO:0000313|WBParaSite:SPAL_0001167900.1};
OS Strongyloides papillosus (Intestinal threadworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Strongyloididae;
OC Strongyloides.
OX NCBI_TaxID=174720 {ECO:0000313|Proteomes:UP000046392, ECO:0000313|WBParaSite:SPAL_0001167900.1};
RN [1] {ECO:0000313|WBParaSite:SPAL_0001167900.1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the sideroflexin family.
CC {ECO:0000256|ARBA:ARBA00005974}.
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DR AlphaFoldDB; A0A0N5C100; -.
DR STRING; 174720.A0A0N5C100; -.
DR WBParaSite; SPAL_0001167900.1; SPAL_0001167900.1; SPAL_0001167900.
DR Proteomes; UP000046392; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-KW.
DR GO; GO:0015075; F:monoatomic ion transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR004686; Mtc.
DR InterPro; IPR004853; Sugar_P_trans_dom.
DR NCBIfam; TIGR00798; mtc; 1.
DR PANTHER; PTHR11153; SIDEROFLEXIN; 1.
DR PANTHER; PTHR11153:SF6; SIDEROFLEXIN-5; 1.
DR Pfam; PF03820; SFXNs; 1.
DR Pfam; PF03151; TPT; 1.
DR SUPFAM; SSF103481; Multidrug resistance efflux transporter EmrE; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 246..264
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 276..298
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 344..364
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 385..404
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 410..431
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 438..457
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 503..525
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 537..558
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 592..611
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 329..609
FT /note="Sugar phosphate transporter"
FT /evidence="ECO:0000259|Pfam:PF03151"
SQ SEQUENCE 642 AA; 72096 MW; 83DBC9DF024C6A84 CRC64;
MTSETIFGFQ KYPEFSISSQ RFPQNTFFGR YLHYLDVIDP RTLFTSDEKL ERCKKLLGDY
KNGMTKNVSN KELWEAKKIC NAILHPDTGE KIFSPFRMAG YVPYGWITVT GMLLPNPTWP
QIIFWQWMNQ SHNAAVNYAN RNCTKPQPTS VYVKAYSIAV STAVGISTAL TYAIKKTNNL
EPIKKLIIQR FVPLPACSLA STFNVLAMRL PEVESGIDVY DKNGTVVGTS KIAAKKAVME
TAYTRAFLPI PLLLAPPCIM PFIEKHKFMK NPRINIFVNA IICTLSFAAS LPIALALFPQ
ESEINTIDLE DDIKKNTTST TLYYNKGIAC GNIINKYVLN DYPYPLSVAM NSLLNSMLYA
SILVCISKIS TKSLKRTPIG YQFRWFLPFA LGKALAVVST YFGLLKVSIS YAQTVKCTMP
IFTVIIARIF LNEKQSNKIY LSLFPIVAGV VLCTFTEINF DEIGLIASLT STSLYSLMNV
LAKKILEDTS INPLQLLSLN SKMAFVLCFP VWFYNEGILF VTSSLDQSQY THPDSKFTFL
LFASGFIAFI QNFCAFTLIH HLTALSYSIA NTSKRIVVIS SSIFFFQNNI TALNILGMTL
SIAGVAFYNR IKHVQGKKKN KFAALRSDYE ETFPNGLTGE LK
//
