ID   A0A0N5C9U3_STREA        Unreviewed;       534 AA.
AC   A0A0N5C9U3;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 35.
DE   SubName: Full=Ras-GEF domain-containing protein {ECO:0000313|WBParaSite:SPAL_0001467200.1};
OS   Strongyloides papillosus (Intestinal threadworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Strongyloididae;
OC   Strongyloides.
OX   NCBI_TaxID=174720 {ECO:0000313|Proteomes:UP000046392, ECO:0000313|WBParaSite:SPAL_0001467200.1};
RN   [1] {ECO:0000313|WBParaSite:SPAL_0001467200.1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
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DR   AlphaFoldDB; A0A0N5C9U3; -.
DR   STRING; 174720.A0A0N5C9U3; -.
DR   WBParaSite; SPAL_0001467200.1; SPAL_0001467200.1; SPAL_0001467200.
DR   Proteomes; UP000046392; Unplaced.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR   CDD; cd06224; REM; 1.
DR   Gene3D; 1.10.840.10; Ras guanine-nucleotide exchange factors catalytic domain; 1.
DR   Gene3D; 1.20.870.10; Son of sevenless (SoS) protein Chain: S domain 1; 1.
DR   InterPro; IPR008937; Ras-like_GEF.
DR   InterPro; IPR000651; Ras-like_Gua-exchang_fac_N.
DR   InterPro; IPR023578; Ras_GEF_dom_sf.
DR   InterPro; IPR001895; RASGEF_cat_dom.
DR   InterPro; IPR036964; RASGEF_cat_dom_sf.
DR   PANTHER; PTHR23113:SF356; FI05912P-RELATED; 1.
DR   PANTHER; PTHR23113; GUANINE NUCLEOTIDE EXCHANGE FACTOR; 1.
DR   Pfam; PF00617; RasGEF; 1.
DR   Pfam; PF00618; RasGEF_N; 1.
DR   SMART; SM00147; RasGEF; 1.
DR   SMART; SM00229; RasGEFN; 1.
DR   SUPFAM; SSF48366; Ras GEF; 1.
DR   PROSITE; PS50009; RASGEF_CAT; 1.
DR   PROSITE; PS50212; RASGEF_NTER; 1.
PE   4: Predicted;
KW   Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658,
KW   ECO:0000256|PROSITE-ProRule:PRU00168}.
FT   DOMAIN          81..213
FT                   /note="N-terminal Ras-GEF"
FT                   /evidence="ECO:0000259|PROSITE:PS50212"
FT   DOMAIN          245..512
FT                   /note="Ras-GEF"
FT                   /evidence="ECO:0000259|PROSITE:PS50009"
FT   REGION          1..21
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   534 AA;  61800 MW;  3DAAAA6553502550 CRC64;
     MLASLYSYPR SQTSSNKESD MFQSKVKIIP RSKSHDRNNI IKKSPIIDEV NATKVPSIND
     INFQNLNLCD SLNSSDIVYN DKDQIIAATA EGLYKLLMPT RNYCPSKDFI FTFLINMRTF
     TNPDDLLKKL LQHCMFELHS DPQNFKKEGR GALFDNIYEI CKEWIYQIPY DFTSNSMRNR
     LKELLNLSAF DDKSKKKISN LFDELTEILN KTSKYESTIF GIEQTIEDPP QITEMLGGIM
     KMTLEPSVVA QQLTHIELER LSVIGVDEFI QALSYGDMDC LDTNKDKGGK NTNNNKDGNA
     VEDTSSKHKV SISIKFYISW FNQLTSFVAT EIMRHARKKY RVKAIEYFID VAKECINIGN
     FNSMMAIVAA LSLPPIARLK KTWSRVEKSK LEILQHQLNP SGNFNSYRST LKAAIWRSEN
     AKLKNEMMII PFFALLLKDL FLVHERSRIP LPNGQLNYVM FSQFADHIAN LNCWRTKKCP
     FKKYPSILQY LLLAPNYSEK NMLWLSYDYE IAEQGIDKLQ YKKLKDEQKK KCSD
//