ID   A0A0N5CCW6_STREA        Unreviewed;       635 AA.
AC   A0A0N5CCW6;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   24-JAN-2024, entry version 26.
DE   SubName: Full=STAS domain-containing protein {ECO:0000313|WBParaSite:SPAL_0001571500.1};
OS   Strongyloides papillosus (Intestinal threadworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Strongyloididae;
OC   Strongyloides.
OX   NCBI_TaxID=174720 {ECO:0000313|Proteomes:UP000046392, ECO:0000313|WBParaSite:SPAL_0001571500.1};
RN   [1] {ECO:0000313|WBParaSite:SPAL_0001571500.1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC       ECO:0000256|RuleBase:RU362052}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU362052}.
CC   -!- SIMILARITY: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
CC       {ECO:0000256|RuleBase:RU362052}.
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DR   AlphaFoldDB; A0A0N5CCW6; -.
DR   STRING; 174720.A0A0N5CCW6; -.
DR   WBParaSite; SPAL_0001571500.1; SPAL_0001571500.1; SPAL_0001571500.
DR   Proteomes; UP000046392; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008509; F:monoatomic anion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0008271; F:secondary active sulfate transmembrane transporter activity; IEA:InterPro.
DR   CDD; cd07042; STAS_SulP_like_sulfate_transporter; 1.
DR   Gene3D; 3.30.750.24; STAS domain; 1.
DR   InterPro; IPR018045; S04_transporter_CS.
DR   InterPro; IPR011547; SLC26A/SulP_dom.
DR   InterPro; IPR001902; SLC26A/SulP_fam.
DR   InterPro; IPR002645; STAS_dom.
DR   InterPro; IPR036513; STAS_dom_sf.
DR   NCBIfam; TIGR00815; sulP; 1.
DR   PANTHER; PTHR11814:SF252; ANION TRANSPORTER SULP-8A; 1.
DR   PANTHER; PTHR11814; SULFATE TRANSPORTER; 1.
DR   Pfam; PF01740; STAS; 1.
DR   Pfam; PF00916; Sulfate_transp; 1.
DR   SUPFAM; SSF52091; SpoIIaa-like; 1.
DR   PROSITE; PS01130; SLC26A; 1.
DR   PROSITE; PS50801; STAS; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362052};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU362052};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU362052}; Transport {ECO:0000256|RuleBase:RU362052}.
FT   TRANSMEM        57..85
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362052"
FT   TRANSMEM        91..108
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362052"
FT   TRANSMEM        129..153
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362052"
FT   TRANSMEM        218..236
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362052"
FT   TRANSMEM        248..267
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362052"
FT   TRANSMEM        293..312
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362052"
FT   TRANSMEM        333..350
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362052"
FT   TRANSMEM        370..388
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362052"
FT   TRANSMEM        395..413
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362052"
FT   TRANSMEM        428..458
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362052"
FT   DOMAIN          484..629
FT                   /note="STAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50801"
SQ   SEQUENCE   635 AA;  71515 MW;  1648A0D763100032 CRC64;
     MDQEEFNKIY GRISSEEKKP KKNGFNLIKT IKSFIPILEW LPNYNVKQNL HGDIIAGMAY
     ASLAGVPPIY GLYSSFFACI VYMFFGTSRH ISIGVFAVVS MMTGATRIKY VNDEIENNNS
     TIIQPGVEVI DSLTLTSTIT FTVGLIQIIM GIFRLSFLTN YMSDSLVSGF TTGAACHVFM
     SQLNKVFGYK IPKHSGIGML IFMLKDVIMN LYKTNFLTLG LATFGLVFLS LGRDYFNPWF
     KKFSSIPVPL ELILVIVTTI ASSFFNFKDN FNVPIVDNIP QGFPVPKLPN FKLIPLVYVD
     CIGISIVCYM FVMSMAKLFA KKHKYKIDSN QELYACGLMS LLSSVFPVYP TGASLSRSSV
     CEMSGAKTQL TVLFSSSLLV VVIMWLGVYL EPLPMCILAS IVIISLKSLF MQFKDLGRLW
     RVSKYDFFVW IVAFATTAFG TVTFGLAVSL GFILLTVVMQ EQFPSMVELG SNENRKYFRP
     IENYTNLSKV NDNITILKFE SPLHFANASR FTEKIGGICA QYNGMLSSMK IIKCEEGLNS
     KEDEILNKKL IKKENKYFII LDCSSISYLD SMGLDVLKKA ESECKSVNVE FYLTNINENI
     IEMFKRCKED EVPKKDNVFP TVNDALECIE SFDKN
//