ID   A0A0N5CFS4_STREA        Unreviewed;       314 AA.
AC   A0A0N5CFS4;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Integrase catalytic domain-containing protein {ECO:0000313|WBParaSite:SPAL_0001670700.1};
OS   Strongyloides papillosus (Intestinal threadworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Strongyloididae;
OC   Strongyloides.
OX   NCBI_TaxID=174720 {ECO:0000313|Proteomes:UP000046392, ECO:0000313|WBParaSite:SPAL_0001670700.1};
RN   [1] {ECO:0000313|WBParaSite:SPAL_0001670700.1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
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DR   AlphaFoldDB; A0A0N5CFS4; -.
DR   STRING; 174720.A0A0N5CFS4; -.
DR   WBParaSite; SPAL_0001670700.1; SPAL_0001670700.1; SPAL_0001670700.
DR   Proteomes; UP000046392; Unplaced.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR   Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR   InterPro; IPR017956; AT_hook_DNA-bd_motif.
DR   InterPro; IPR001584; Integrase_cat-core.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR036397; RNaseH_sf.
DR   PANTHER; PTHR41694; ENDOGENOUS RETROVIRUS GROUP K MEMBER POL PROTEIN; 1.
DR   PANTHER; PTHR41694:SF3; RNA-DIRECTED DNA POLYMERASE-RELATED; 1.
DR   PRINTS; PR00929; ATHOOK.
DR   SMART; SM00384; AT_hook; 2.
DR   SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR   PROSITE; PS50994; INTEGRASE; 1.
PE   4: Predicted;
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..27
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           28..314
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5005895811"
FT   DOMAIN          1..120
FT                   /note="Integrase catalytic"
FT                   /evidence="ECO:0000259|PROSITE:PS50994"
FT   REGION          255..314
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        289..314
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   314 AA;  35974 MW;  F0756B31B2A58B48 CRC64;
     MKLNTFTTIK LLKLSFFLLG FPHTLKTDNG PAFIADLFKN FCKTYNIEHY AVSAYNHQGN
     GIVERFNRTI RESLRIYKEK DISDIINSTQ YVHNFSYTTN QEGKPKEYIL STADRFTNES
     YTNTTLSGRQ NLLQFIKEKL KPTPTDGTST SKEFATLKVG TIVYKKIVNA HKNNEQFHGP
     YRILEHLHGD TYLIGMVTRS NRKTGQIERC NARFLKLAPL AIQHTLNDES HILDNDNHHN
     TRVISFPQET IIKKGRGRPR KVLPTNNETP NTDEIIIQPK KGRGRPKKLV SMNNSNITTI
     DPQTQQPTRG SGRP
//