ID   A0A0N5D4U0_THECL        Unreviewed;       415 AA.
AC   A0A0N5D4U0;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   SubName: Full=Orn_Arg_deC_N domain-containing protein {ECO:0000313|WBParaSite:TCLT_0000799901-mRNA-1};
GN   ORFNames=TCLT_LOCUS7988 {ECO:0000313|EMBL:VDN05500.1};
OS   Thelazia callipaeda (Oriental eyeworm) (Parasitic nematode).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Spiruromorpha; Thelazioidea; Thelaziidae; Thelazia.
OX   NCBI_TaxID=103827 {ECO:0000313|Proteomes:UP000046394, ECO:0000313|WBParaSite:TCLT_0000799901-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:TCLT_0000799901-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDN05500.1, ECO:0000313|Proteomes:UP000276776}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933};
CC   -!- SIMILARITY: Belongs to the Orn/Lys/Arg decarboxylase class-II family.
CC       {ECO:0000256|ARBA:ARBA00008872, ECO:0000256|RuleBase:RU003737}.
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DR   EMBL; UYYF01004567; VDN05500.1; -; Genomic_DNA.
DR   STRING; 103827.A0A0N5D4U0; -.
DR   WBParaSite; TCLT_0000799901-mRNA-1; TCLT_0000799901-mRNA-1; TCLT_0000799901.
DR   OMA; NDGLYGC; -.
DR   Proteomes; UP000046394; Unplaced.
DR   Proteomes; UP000276776; Unassembled WGS sequence.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0006596; P:polyamine biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.20.20.10; Alanine racemase; 1.
DR   InterPro; IPR009006; Ala_racemase/Decarboxylase_C.
DR   InterPro; IPR022643; De-COase2_C.
DR   InterPro; IPR022644; De-COase2_N.
DR   InterPro; IPR000183; Orn/DAP/Arg_de-COase.
DR   InterPro; IPR002433; Orn_de-COase.
DR   InterPro; IPR029066; PLP-binding_barrel.
DR   PANTHER; PTHR11482; ARGININE/DIAMINOPIMELATE/ORNITHINE DECARBOXYLASE; 1.
DR   PANTHER; PTHR11482:SF6; ORNITHINE DECARBOXYLASE 1-RELATED; 1.
DR   Pfam; PF02784; Orn_Arg_deC_N; 1.
DR   Pfam; PF00278; Orn_DAP_Arg_deC; 1.
DR   PRINTS; PR01179; ODADCRBXLASE.
DR   PRINTS; PR01182; ORNDCRBXLASE.
DR   SUPFAM; SSF50621; Alanine racemase C-terminal domain-like; 1.
DR   SUPFAM; SSF51419; PLP-binding barrel; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000276776}.
FT   DOMAIN          49..275
FT                   /note="Orn/DAP/Arg decarboxylase 2 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02784"
FT   DOMAIN          276..382
FT                   /note="Orn/DAP/Arg decarboxylase 2 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00278"
SQ   SEQUENCE   415 AA;  46757 MW;  234B54FE51EE6BB5 CRC64;
     MEDTKQFILP IKKSSDFFDV IRKLITAKEA QNNNAPFFVM NMRLITIVVK NWYSKMPNIE
     PFYPIRCNSD HVFLKLLTHN GEMGLCCSNR EEAEIVPNLI SVDRIIYHNP LWTRGNIRHA
     RECGIKTFIV ESEDDLRRFT TFYPDANIIL RVVMDQKLIS DPLTADNFNV ERAAHLLSKT
     ENSSLNISVR SNGPSPTMYS YAIAQCRRLF DIGSEFGHKF CILDLGEQFP SITATSGLSF
     DQVADSVRVS LSLLFPSKLF KHVKIIARPG TYFAASSCSF VTRIIGKQVV DSSILTNYGN
     CCSNADSTAY IYQINEGFYG AFGCKLLTHC DPTCSPLIDD GGKLDTFAAI VGPDPCHNDV
     VLPLTRLPVL QVNDWLIWHD MGAYTMGNCS TLNGENIPLP TIHYYWESDT TTFVF
//