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Database: UniProt
Entry: A0A0N5DTM2_TRIMR
LinkDB: A0A0N5DTM2_TRIMR
Original site: A0A0N5DTM2_TRIMR 
ID   A0A0N5DTM2_TRIMR        Unreviewed;      1790 AA.
AC   A0A0N5DTM2;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   25-OCT-2017, entry version 13.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|WBParaSite:TMUE_s0063002300};
OS   Trichuris muris (Mouse whipworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC   Trichocephalida; Trichuridae; Trichuris.
OX   NCBI_TaxID=70415 {ECO:0000313|Proteomes:UP000046395, ECO:0000313|WBParaSite:TMUE_s0063002300};
RN   [1] {ECO:0000313|Proteomes:UP000046395}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Edinburgh {ECO:0000313|Proteomes:UP000046395};
RA   Hoang H.T., Killian M.L., Madson D.M., Arruda P.H.E., Sun D.,
RA   Schwartz K.J., Yoon K.;
RL   Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Proteomes:UP000046395}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Edinburgh {ECO:0000313|Proteomes:UP000046395};
RA   Foth B.J., Tsai I.J., Reid A.J., Bancroft A.J., Nichol S., Tracey A.,
RA   Holroyd N., Cotton J.A., Stanley E.J., Zarowiecki M., Liu J.Z.,
RA   Huckvale T., Cooper P.J., Grencis R.K., Berriman M.;
RT   "The whipworm genome and dual-species transcriptomics of an intimate
RT   host-pathogen interaction.";
RL   Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|WBParaSite:TMUE_s0063002300}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Edinburgh {ECO:0000313|WBParaSite:TMUE_s0063002300};
RG   Helminth Genomes Consortium;
RL   Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
RN   [4] {ECO:0000313|WBParaSite:TMUE_s0063002300}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
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DR   WBParaSite; TMUE_s0063002300; TMUE_s0063002300; TMUE_s0063002300.
DR   Proteomes; UP000046395; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005261; F:cation channel activity; IEA:InterPro.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR028823; NALCN.
DR   PANTHER; PTHR10037:SF214; PTHR10037:SF214; 1.
DR   Pfam; PF00520; Ion_trans; 4.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000046395};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000046395};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     73     90       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    102    121       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    222    244       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    307    328       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    340    362       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    425    445       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    550    576       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    617    641       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    926    944       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    964    987       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    999   1016       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1061   1080       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1145   1162       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1174   1201       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1255   1274       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1294   1316       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1328   1346       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1358   1375       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1396   1420       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1484   1507       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       73    371       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN      424    646       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN      925   1205       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN     1256   1518       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   COILED      844    867       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   1790 AA;  206835 MW;  7411EC5ECC72FC8C CRC64;
     MSGKSRGRVL VQHLQVRLGA ILDSVTKAAA ISSAMLARKQ SYKGIETTAA DHPFDSAKEA
     ADVRWYDKKI SKAFMITACL LSLISVSLNT PSTFESLPFL QLVTYTIDVV ITLLFTVEAG
     IKIKHKGFLR ENVGYLHDRW CQFDFFMVIC HWISVLTETT ELLLNLFLDS FNRAGHSDHI
     RLLGLLRAPR PLILVRMIRS LLKIQLPRNR ISQIFKRSSQ QVYNVTIFFL FFMSLYAILG
     VQFFGRMDYH CVKNGTDPRN VSIRDLAIPD TYCSTDDSGY QCPKGMQCVR LKLSDAIEGY
     YGMFNDFAHS VFSVYMAASQ EGWVYVMYDC IDSLPSWKAF FYFTTLIFFL AWLVKNVFIA
     VITETFAEIR VQFSQMWGSR ERLTDVEIRQ ILEKKENAWR LIALDAKMPK GWAPKVLLDF
     HGSTAFQIII MVLVLSNAFI HASFVHKHDG SDVRRKQIYY YIECGFTLFF DLECLFKIWC
     LTWHGYISRG LHKFEFILCV GSTLNIIKPL YDMNVFTYCQ VSRVLRLIKA FPMLEDFVYK
     IFGPGKKLGG IILFTVALLL LTSSISLQLF CFVYNLDRFT TLPQAIMSMF QIMTQEEWTE
     VVVETMRAVG DKLSPLVAIY FVTYHLLVTL IVLSLFVAVI LDNLEMDEEL KKVKQLKARE
     HTTSSRTKLP LRLRVFTHFP DRPQMVIVKR IPSEFPLPKI RDSFTKQYAN DEQNEGEDEQ
     EKVRFGVRKA INERVKKLRI RKRAKIRQTG HLSTITGINC VLNDSNKARI LLSDSFGMLP
     VLNRTAGRKV SSTELRGRKS TKIQVTAHGA TLKQLYHHLK ENGDLFSPDD YSEGKSKVQG
     EIDIKAIQQK KRQAEMARSR LQEEMKENHP FFDRPLFVFD RENKLRKICQ LIVYAKYLPV
     KTNPTTQKPV HQKYQEIREL LGMMTYLDWT MFFLTCVSCI SMLFEKPWPL DGRHLIMNNG
     YIQIADYIFV IGMTFELLVK VFANGLFFTP KAVIRDFGGI LTVFIYATSL IFLIWMPKDV
     RPSSGAQLLM VFRAMRPLRI YTLVPHIRRV VVELFKGFRE ILLVTILLVV LMFIFASYGV
     QIAGGKLAKC NDLTIKTRKE CVGYFYQYVQ VTKLNIAGQG DPKLHPKWLV PRIWANPRNF
     NFDHIGNAML ALFEILSFKG WTVMRDVILE RLGAWAAIFV HLYVFIGCMI GLTLFVGVVI
     ANYTENRGTA LLTVDQRRWN DLKNRLKMAQ PLFVPPRPPE SSKFRKFMYD LSMSLYFKRF
     FTICVLLNSM LLFVPWSVEE EEHPETKDTL KALIALSAIF TLLFFVEIIC KIVAFTHRGF
     WQSFRNRVDL IITLLGLAWC LLHFFVALPT EKKKLREVTY MFGYSIVVLR FFTIVGRHTT
     LKMLMLTVVM SMFRSFFIIM AMFLLMLFYA YAGVILFGMV KYGQAVNRHA NFRSATNALT
     VLFRIVTGED WNEIMHDCMR SPPSCWYYEG AVLWETDCGN YHGAVIYFCS FYLIITYIVL
     NLLVAIIMEN FSLFYSSEED ALLSYADIRN FQNVWNIVDK EQKGCIPVRR VKFLLHLLKG
     RLEVDPEKDR VLFKHMCYEM EQLRYSEEVT FHDVLSMLSY RSVDIRKHLQ LEELVQREEL
     EYMIEEDVAK LTIRSWLEKC LRRMRQKEQN FSIINSLRAA TAGLLEAAEQ VEANKVEPPK
     PVPAVKPGQR GSVSNAIAES TKRLMSAIRG SHEKINGRSA SIKLRSKPLT GVAENSEDPA
     QTESSPVHVR STSHSNLLGT TAQHSVLEQE YLAELVDVKH WWNEAIENVA
//
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