ID A0A0N8H6A0_9HYPO Unreviewed; 535 AA.
AC A0A0N8H6A0;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=Phosphotransferase {ECO:0000256|RuleBase:RU362007};
DE EC=2.7.1.- {ECO:0000256|RuleBase:RU362007};
GN ORFNames=AK830_g8170 {ECO:0000313|EMBL:KPM38388.1};
OS Neonectria ditissima.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Neonectria.
OX NCBI_TaxID=78410 {ECO:0000313|EMBL:KPM38388.1, ECO:0000313|Proteomes:UP000050424};
RN [1] {ECO:0000313|EMBL:KPM38388.1, ECO:0000313|Proteomes:UP000050424}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=R09/05 {ECO:0000313|EMBL:KPM38388.1,
RC ECO:0000313|Proteomes:UP000050424};
RA Gomez-Cortecero A., Harrison R.J., Armitage A.D.;
RT "Draft genome of a European isolate of the apple canker pathogen Neonectria
RT ditissima.";
RL Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the hexokinase family.
CC {ECO:0000256|ARBA:ARBA00009225, ECO:0000256|RuleBase:RU362007}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPM38388.1}.
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DR EMBL; LKCW01000135; KPM38388.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0N8H6A0; -.
DR STRING; 78410.A0A0N8H6A0; -.
DR OrthoDB; 5481886at2759; -.
DR UniPathway; UPA00109; UER00180.
DR Proteomes; UP000050424; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0005536; F:glucose binding; IEA:InterPro.
DR GO; GO:0004396; F:hexokinase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006096; P:glycolytic process; IEA:UniProtKB-UniPathway.
DR GO; GO:0001678; P:intracellular glucose homeostasis; IEA:InterPro.
DR Gene3D; 3.30.420.40; -; 1.
DR Gene3D; 3.40.367.20; -; 1.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR001312; Hexokinase.
DR InterPro; IPR022673; Hexokinase_C.
DR InterPro; IPR022672; Hexokinase_N.
DR PANTHER; PTHR19443; HEXOKINASE; 1.
DR PANTHER; PTHR19443:SF24; HEXOKINASE YLR446W-RELATED; 1.
DR Pfam; PF00349; Hexokinase_1; 1.
DR Pfam; PF03727; Hexokinase_2; 1.
DR PRINTS; PR00475; HEXOKINASE.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR PROSITE; PS51748; HEXOKINASE_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU362007};
KW Glycolysis {ECO:0000256|RuleBase:RU362007};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000256|RuleBase:RU362007};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU362007};
KW Reference proteome {ECO:0000313|Proteomes:UP000050424};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU362007}.
FT DOMAIN 67..258
FT /note="Hexokinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00349"
FT DOMAIN 265..529
FT /note="Hexokinase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03727"
SQ SEQUENCE 535 AA; 58602 MW; DDCD1927BD232252 CRC64;
MATLRKQFIA ALFKSLIRGK SLFQAILAYW TRSLAVPVDR KNRVTASSHR SAEEFLKEAE
ALFLDPVSQH GLQRLSHGMR KQFVERLQAD MECMLPSYTH QLPHGDEKGH FLALDVGGST
LRVALVELRG RMSEGGEESR IVSMRNFTIS HEIKDLEGMA FFDWMAARIK DTLAGELEQH
QNPDEPLLMA MAWSFPIEQT SLASGKIQVM GKGFLAHDGL LGQDLGQVIK TACGNQGLNV
ELRAILNDSS ACLLSESYSH PSTRFGLILG TGVNIAAYLP VSAIGQPKFG QRPAEWTHLI
VNSEIGMFGH DILPLTRWDR QLLQGHPRPT FQPLEHLVSG MYLGEICRFG LIEAIESVGV
FGGVVPSSLR EPYSLATETL SKVQSDTSIG FSDACQEFSS RHPSSHTPTA SDLSFLGQLA
SIISIRSSAL VATSVYTFWR LRIDLQADWV ETLPECSPLR LSAEADKNLA ETTVAFNGSV
IENYPGYLKS CQQYLDDLVA SQKGNDNAYA VKLVSARESS LMGAAVALAS VKGSG
//
