GenomeNet

Database: UniProt
Entry: A0A0N8K2D6_9TELE
LinkDB: A0A0N8K2D6_9TELE
Original site: A0A0N8K2D6_9TELE 
ID   A0A0N8K2D6_9TELE        Unreviewed;      4992 AA.
AC   A0A0N8K2D6;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   22-NOV-2017, entry version 11.
DE   SubName: Full=Ryanodine receptor 1-like {ECO:0000313|EMBL:KPP77441.1};
DE   Flags: Fragment;
GN   ORFNames=Z043_103133 {ECO:0000313|EMBL:KPP77441.1};
OS   Scleropages formosus (Asian bonytongue).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Osteoglossocephala;
OC   Osteoglossomorpha; Osteoglossiformes; Osteoglossidae; Scleropages.
OX   NCBI_TaxID=113540 {ECO:0000313|EMBL:KPP77441.1, ECO:0000313|Proteomes:UP000034805};
RN   [1] {ECO:0000313|EMBL:KPP77441.1, ECO:0000313|Proteomes:UP000034805}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Aro1 {ECO:0000313|EMBL:KPP77441.1};
RA   Tan M.H., Gan H.M., Croft L.J., Austin C.M.;
RT   "The genome of the Asian arowana (Scleropages formosus).";
RL   Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KPP77441.1}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; JARO02000776; KPP77441.1; -; Genomic_DNA.
DR   Proteomes; UP000034805; Unassembled WGS sequence.
DR   GO; GO:0005623; C:cell; IEA:GOC.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005219; F:ryanodine-sensitive calcium-release channel activity; IEA:InterPro.
DR   CDD; cd12877; SPRY1_RyR; 1.
DR   CDD; cd12878; SPRY2_RyR; 1.
DR   CDD; cd12879; SPRY3_RyR; 1.
DR   Gene3D; 1.25.10.30; -; 2.
DR   InterPro; IPR001870; B30.2/SPRY.
DR   InterPro; IPR013320; ConA-like_dom_sf.
DR   InterPro; IPR011992; EF-hand-dom_pair.
DR   InterPro; IPR002048; EF_hand_dom.
DR   InterPro; IPR014821; Ins145_P3_rcpt.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR035910; IP3R_RIH_dom_sf.
DR   InterPro; IPR036300; MIR_dom_sf.
DR   InterPro; IPR016093; MIR_motif.
DR   InterPro; IPR013662; RIH_assoc-dom.
DR   InterPro; IPR000699; RIH_dom.
DR   InterPro; IPR013333; Ryan_recept.
DR   InterPro; IPR003032; Ryanodine_rcpt.
DR   InterPro; IPR015925; Ryanodine_recept-rel.
DR   InterPro; IPR009460; Ryanrecept_TM4-6.
DR   InterPro; IPR035761; SPRY1_RyR.
DR   InterPro; IPR035764; SPRY2_RyR.
DR   InterPro; IPR035762; SPRY3_RyR.
DR   InterPro; IPR003877; SPRY_dom.
DR   PANTHER; PTHR13715; PTHR13715; 1.
DR   Pfam; PF13833; EF-hand_8; 1.
DR   Pfam; PF08709; Ins145_P3_rec; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF02815; MIR; 1.
DR   Pfam; PF08454; RIH_assoc; 1.
DR   Pfam; PF06459; RR_TM4-6; 1.
DR   Pfam; PF01365; RYDR_ITPR; 2.
DR   Pfam; PF02026; RyR; 4.
DR   Pfam; PF00622; SPRY; 3.
DR   PRINTS; PR00795; RYANODINER.
DR   SMART; SM00472; MIR; 4.
DR   SMART; SM00449; SPRY; 3.
DR   SUPFAM; SSF100909; SSF100909; 2.
DR   SUPFAM; SSF47473; SSF47473; 1.
DR   SUPFAM; SSF49899; SSF49899; 2.
DR   SUPFAM; SSF82109; SSF82109; 2.
DR   PROSITE; PS50188; B302_SPRY; 3.
DR   PROSITE; PS50919; MIR; 5.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000034805};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Receptor {ECO:0000313|EMBL:KPP77441.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000034805};
KW   Repeat {ECO:0000256|SAAS:SAAS00903904};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4281   4299       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4514   4534       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4597   4619       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4735   4756       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4794   4814       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4873   4896       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       81    136       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      143    188       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      196    251       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      257    314       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      322    379       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      581    781       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   DOMAIN      997   1193       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   DOMAIN     1304   1515       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   COILED     3626   3653       {ECO:0000256|SAM:Coils}.
FT   NON_TER       1      1       {ECO:0000313|EMBL:KPP77441.1}.
SQ   SEQUENCE   4992 AA;  565590 MW;  A661BCD61124D98B CRC64;
     DDQVVLQCTA TVLKEQIKLC LSCEGFGNRL CFLEPTSNAQ NVPPDLAICC FILEQSLSVR
     ALQEMLANTV EMNESSQGGG HRTLLYGHAI LLRHSHSGMY LSCLTSSRSL TDKLACDVGL
     QEDSTGEACW WTIHPASKQR SEGEKVRVGD DLILVSVSSE RYLHLSYASG DLMVDASFMQ
     TLWNMNPVCS GCEMAEGYLT GGHVLRLFHG HMDECLAIPS ADQGEDQRTT AQYEAGAVCS
     QARSLWRLEP LRIGWSGSHM KWGQPFRVRH VTTGRYLCLD EEKGLMVLDP KRANTKMSAF
     CFRASKEKSE VAPKRDVEGM GTPEIKYGES MCFVQHVSTG LWLTYAALDA KSARLGTPKR
     RAILHQEGHM DDGLCPSRSQ MEESQAARMI YSTTGLFTQF IKELDSLSAK NKTPTPLTLP
     LDSVVLSLQD LIHYFRYPEE DLEHEEKQTK LRSLRNRQNL FQEEGMITLV LNCVDRLNVY
     NTSAHFAEFA GEEAGEFWKE IVNLLYELLA SLIRGNRANC ALFCDNLDWL VSKLDRLEAS
     GGILEVLYCV LIESPEVLNI IQENHIKSII SLLDKHGRNH KVLDVLRSLC VCNGVAVRSN
     QNLITENLLP GRDLLLQTNI VNYVTSMRPN IFLGTCEGST QYKKWYFEMI VDYVEPFVTA
     QAAQLRVGWA LTVGYSPYPG GGEGWGGNGV GDDLYSYGFD GLHLWSGHVP RAVASPNQHI
     LAGDDVVSCC LDLSVPSISF RINGHPVQGM FENFNVDGLF FPVISFSAGI KARFLLGGRH
     GEFKFLPPPG YAPCYEALLP KERMRIEPVK EYKRDFNGIC NLLGPMQSLT NTSFTPCPVD
     TIQIVLPPHL ERIREKLAEN IHELWAVTRI EQGWTYGEFR DDNKKLHPCL VDFQSLPEPE
     RNYNLQMSGE TIKTLLALGC HVGMGDEKAE ENLRKIKLPK TYMMSNGYKP VPLDLSHVKL
     TPNQNTLVEK LAENGHNVWA RDRVRQGWTY SIVQDIMNKR NPRLVPYNLL DERTKKTNRD
     SVCAAVRTLI GYGYNIEPPD QESSGHGVES ARGDKIRLFR AEKSYAVTQG KWYFEFEAVT
     VGEMRVGWAR PSVRADTELG ADELAYVFNG NKAQRWHIGN EPFGRQWQPG DVVGCMIDLS
     EMNIMFTLNG EMLISDSGSE MAFKDIEVGE GFIPVCSLGP SQVGRINLGQ NVSSLHYFTI
     CGLQEGFEPF AINMKRDITM WFSKSLPQFL PVPADHNHIE NANTDMLFMR MSVPVQFYET
     FKVPAGTTPL TRALTIPEDE ALEVEPDSEF EVLKKSASRK EQEEKEPSVA KEVPAVKGEN
     EKDVTTEKTK KRGFLFKAKK AALITPPPVV PTVPRLVEDV VPDDRDDPEI ILSTTTYFYS
     VRIFAGQEPS GVWVGWVTPD FHQYDLNFEL SKVRTVTVTV GDEKGNIHDS MKHSNCYMVW
     GAEFSNSSQQ ARFSQEDLVI GCLVDLATGL LNFTANGKEV NTFFQVEPNT KLFPAVFVLP
     SSQNMLQVEL GKLKNIMPLS AAMFHSECKN SVPQCPPRLD FQMLTPVIWS RVPNLFLTPE
     VTRVSERHGW MVECTEPLTL MALHIPEENR CIDILELSER MDMLKFHYHT LKLYCAVCAL
     GNNRVAHALC SHVDESQLFY AIESTYLPGP LRSGYYDLLI SMHLESAKRA RLLTNREFIV
     PMTEETLSIS LYGDKEKGHA FPGVGLTTCL RPKPHFSPVG FIGTDLDIYT LSPVIPLQVM
     KIKAISMLTE AVFDGSQAMR DPVGGSVEFH FVPILKLIST LLIMGVFDDE DVTHILKMID
     PSVFTEGGDA EAPEEEEGGE KGEGEEGATT EERGEAKVQE EELEGELVDE GVGDEEEEEL
     KKLVSGKEEL EEGHGDKEGE SKGEKVDGEM AAEEKEKESG AGEGEAKEED AGPEEGLLQM
     KLPETVKLQM CTLLQYFCDC ELRHRVEAII AFSDSYVRLL QANQKQRYND LMQAVNMTAA
     ETARKTREFR SPPLEQVILL TSCKNVSDDE KCSIPDEIRE TLQNFHKELL SHCGVQIEEE
     EEEEEVDTSL HGRLLSLVEK VKNFRKKKEE EEPEPEEEPK PSTLQELISH TMIHWAQESF
     IQNPELVRLM FSLLHRQYDP LGELMRALPK AYAINAVSVQ DTMDLLECLG QIRSLLIVQM
     GPEEETLMIQ SIGNIMNNKV FYQHPNLMRA LGMHETVMEV MVNVLGAGGE EIRFPQMVTN
     CCRFLCYFCR ISRQNQRSMF DHLSYLLENS GIGLGMRGST PLDVAAASCI DNNELALALQ
     EQDLEKVVRY LAGCGLQSCP ILLSKGYPDI GWNPCGGERY LDFLRFAVFV NGESVEENAN
     VVVRLLIRRP ECFGPALRGE GGSGLLAAIE DAIKISEDPA RDGPTPKKDR RFMFGGEQQE
     ENRVHLGNAI MSFYSALIDL LGRCAPEMHL IQAGKGEALR IRAILRSLVP IEDLVGVISL
     PIQIPAFGKV EPKMSASFVP DHKASMVLFL DRVYGIDNQD FLLHVLEVGF LPDMRAAASL
     DTAAFSTTEM ALALNRYLCS AVLPLVTKCA PLFAGSDHRA IMIDSMLHTI YRLSRGRALT
     KAQRDIIEEC LMSLCKYLRP SMLQHLLRRL VFDVPILNEY AKMPLKLLTN HYERCWKYYC
     LPNGWANFGV SSEEELHLSR KLFWGIFESL AHKKFDAELF KIAMPCICAI AGAIPPDYVD
     ASYSHTEKKA SVDAEGNFDP RPVETTNTII PEKLDAFINK YAEHTHDKWA FEKIQNNWTY
     GETLDENAKT HPMLRPYKTF SEKDKEIYRW PIKESIKAML AWEWNLEKAR DGDEEKTEKK
     TRKISQTAQM TYDPSHGYSP QPIDISGMAI SRELQSMAEQ LAENYHNTWA RKKKLELQAK
     GGGTHPLLVP YDTLTAKEKA RDREKAQDLL KFLQLNGYAV TRGLKDMEQD ISSIEKRFAY
     GFLKKLLKWL DIAQEFIAHL EAVVSSGRVE KSPHEQEIKF FAKILLPLIN QFFKNHCLYF
     LSTPAKLLGS GGHSSNKEKE MIASIFCKMA ALVRHRVSLF GTDAAAVVNC LHILTVMKSG
     PEIVKAGLRS FFESAADDIE KMVENLKLGK VSSRNQVKGV SQNMNYTTVA LLPVLTSLFD
     HIAQHQFGDD VILDDLQISC YRIMCSIYSV GTIKTPHMEK HRPALGECLA HLAAAMPVAF
     VEPYFNEFNA YSELCPDIPE LDALMKEIRD LAESGARYTE MPHIIEVTLP MLCNYLPRWW
     ERGVENFPEQ EGQLCTEVTS EHLNQLLGSI MKIVVNNLGI DEASWMKRLA VFTQPIVSRA
     KPEMLKSHFI PTMEKLRKRC GKVVAEEDQM RMEGKMESDS EQSTIRDEFA VLCRDLYALY
     PLLIRYVDNN RARWLTCPDP DAEDLFRMVG EVFIFWSKSH NFKREEQNFV VMNEINNMSF
     LTADSKSKMS KQDGQHPLNP FMCTQGSGSD VERNKKKRRG DRYSVQTSLI VAALKKLLPI
     GLNMCSPADQ ELINLAKVRY SLKDTDEEVR EFLQNNLHFQ GKVEDPSMRW QMALYKEAAG
     KAEDADAPEK VVKRVQEVSA VLYHIDLTEH PFKSKKMAWH KLLSKQRRRA VVACFRMTPL
     YNIPRHRASN MFLDGYKRNW IENEGYSFED KMINDLSQAM EQEEEEEEET ETKPDPLHQL
     ILHFSRTALT EKSKLDEDYL YMAYADIMAK SCHIDEEGKE EEEAEEMTFE EKEMEKQRLL
     YQQSRLHNRG AAEMVLQMIS ACKGEPGAMV SSTLKLGISI LNGGNSDVQQ KMLDYLKDKK
     DVGFFLSVQA LMQTCSVLDL NAFERQNKAE GLGMVSEEGT KEKVMADNEF TCDLFRFLQL
     LCEGHNNDFQ NYLRTQTGST TTINIIICTV DYLLRLQESI SDFYWYYSGK DIIDEPGKRN
     FSKAMTVAKQ VFNSLTEYIQ GPCTGNQQSL AHSRLWDAVV GFLHIFAHMM MKLAQDSSQI
     GLLKELLDLQ KDMVVMLLSL LEGNIVNGTI ARQMVDMLVE SSSNVEMILK FFDMFLKLKD
     IVASDAFRDY VTDPRGLISK KDFQKAMDSQ KQYSPSEIQF LLSCSEADEN EMINFEEFAD
     RFQEPAKDIG FNIAVLLTNL SEHVPHDSRL QNFLEQAESV LNYFRPFLGR IEIMGASKRI
     ERIYFEISEV NRTQWEMPQV RESKRQFIFD VVNEGGESEK MELFVNFCED TIFEMNIAAQ
     ISEQEEEEKD DDDEEEGAGE GGEEGSGEGE GENGEKAPPE STSAFADFIN SVISFFGMFT
     FRNLRRQYRR IRKMTVKEMV VALATFFWTI FIGILQFIYS ICRGFFLLVW NTLFGGRLVE
     GAKKMTVTEI LASMPDPTQD EVHGDLPAEP GARVEQEAGG VADLMEGGGV EEEEQETKEK
     EGGRIPGFDT PGGLGDMGEP ATVEPPTPEG SPITKRKLLD SDEGGAEQEV TEEAPPEPEK
     ADAENGEKVE KEAEAEPEAE PEPKAEEPEK EEEQTEKVKT KKDKKSETED GFELWNELEI
     QRNKFMNYLS RNFYNLRFLA LFIAFALNFI LLFYKVSDSP PGEEDFEGSA MFEGSAMFEG
     SGGEAEGSGM EDGDEEDEEN GVVYYFLEES TGYMEPALAF LGIVHTIISF LCIIGYNCLK
     VPLVIFKREK ELARKLEFDG VYVTEQPEDD DIKGQWDRLV LNTPTFPNNY WDKFVKRKVL
     EKYGDIYGRE RIAELLGMDL ASLDVSTQQQ KKPKPDNSVF TWITSFDIKY QIWKFGVVFT
     DNTFLYLVWY LVMSLLGHYN NFFFAAHLLD IAMGVKTLRT ILSSVTHNGK QLMMTVGLLA
     VVVYLYTVVA FNFFRKFYNM SEDEDEPDMK CDDMMTCYLF HMYVGVRAGG GIGDEIEDPA
     GDEYELYRVV FDITFFFFVI VILLAIIQGL IIDAFGELRD QQEQVKEDME TKCFICGIGS
     DYFDTTAHGF ETHTMEEHNL ANYMFFLMYL INKDETEHTG QESYVWKMYQ ERCWDFFPAG
     DCFRKQYEDQ LG
//
DBGET integrated database retrieval system