ID A0A0N9IDJ8_9PSEU Unreviewed; 316 AA.
AC A0A0N9IDJ8;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Glyoxylate reductase {ECO:0000313|EMBL:ALG13136.1};
GN ORFNames=AOZ06_45365 {ECO:0000313|EMBL:ALG13136.1};
OS Kibdelosporangium phytohabitans.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Kibdelosporangium.
OX NCBI_TaxID=860235 {ECO:0000313|EMBL:ALG13136.1, ECO:0000313|Proteomes:UP000063699};
RN [1] {ECO:0000313|EMBL:ALG13136.1, ECO:0000313|Proteomes:UP000063699}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KLBMP1111 {ECO:0000313|EMBL:ALG13136.1,
RC ECO:0000313|Proteomes:UP000063699};
RA Qin S., Xing K.;
RT "Genome sequencing of Kibdelosporangium phytohabitans.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the D-isomer specific 2-hydroxyacid
CC dehydrogenase family. {ECO:0000256|RuleBase:RU003719}.
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DR EMBL; CP012752; ALG13136.1; -; Genomic_DNA.
DR RefSeq; WP_054295025.1; NZ_CP012752.1.
DR AlphaFoldDB; A0A0N9IDJ8; -.
DR STRING; 860235.AOZ06_45365; -.
DR KEGG; kphy:AOZ06_45365; -.
DR OrthoDB; 9793626at2; -.
DR Proteomes; UP000063699; Chromosome.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR CDD; cd05301; GDH; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR006139; D-isomer_2_OHA_DH_cat_dom.
DR InterPro; IPR029753; D-isomer_DH_CS.
DR InterPro; IPR006140; D-isomer_DH_NAD-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR10996; 2-HYDROXYACID DEHYDROGENASE-RELATED; 1.
DR PANTHER; PTHR10996:SF257; GLYCERATE DEHYDROGENASE HPR, PEROXISOMAL; 1.
DR Pfam; PF00389; 2-Hacid_dh; 1.
DR Pfam; PF02826; 2-Hacid_dh_C; 1.
DR SUPFAM; SSF52283; Formate/glycerate dehydrogenase catalytic domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00670; D_2_HYDROXYACID_DH_2; 1.
DR PROSITE; PS00671; D_2_HYDROXYACID_DH_3; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU003719};
KW Reference proteome {ECO:0000313|Proteomes:UP000063699}.
FT DOMAIN 4..311
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase
FT catalytic"
FT /evidence="ECO:0000259|Pfam:PF00389"
FT DOMAIN 111..279
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase NAD-
FT binding"
FT /evidence="ECO:0000259|Pfam:PF02826"
SQ SEQUENCE 316 AA; 33948 MW; 39929DC3D13C3762 CRC64;
MAKVLVTREM VDEAVRALTG RCELDLYTGP PEAIPRDEFL ERAAGKDGLL TMLSERVDAE
LLDAAGPQLR VVANHGVGYD NIDVAECTKR GVLVANTPDV LTEATADLAW ALILASVRRI
AEGDRFLRTG KPWIWGPRMM LGQELHGRTL GIVGYGRIGR ATARRAEGFG MRVIHTARAG
SADSVPFGTL VAESDVISIH APLTPETRHL FDADVFRRMK PTAVLVNTAR GPLVDEAALA
EALRAGEIFA AGLDVFEREP EVEKALLALD TVTIVPHLGS ATAQTRAAMG LFAVENVLDG
VAGHRPRALV NPEVLT
//
