ID A0A0P0CST0_9BACT Unreviewed; 383 AA.
AC A0A0P0CST0;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=3-hydroxybutyryl-CoA dehydrogenase {ECO:0000313|EMBL:ALJ00542.1};
GN ORFNames=DC20_18165 {ECO:0000313|EMBL:ALJ00542.1};
OS Rufibacter tibetensis.
OC Bacteria; Bacteroidota; Cytophagia; Cytophagales; Hymenobacteraceae;
OC Rufibacter.
OX NCBI_TaxID=512763 {ECO:0000313|EMBL:ALJ00542.1, ECO:0000313|Proteomes:UP000061382};
RN [1] {ECO:0000313|EMBL:ALJ00542.1, ECO:0000313|Proteomes:UP000061382}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1351 {ECO:0000313|EMBL:ALJ00542.1,
RC ECO:0000313|Proteomes:UP000061382};
RA Dai J.;
RT "Complete genome sequence of Rufibacter tibetensis strain 1351t, a
RT radiation-resistant bacterium from tibet plateau.";
RL Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP012643; ALJ00542.1; -; Genomic_DNA.
DR RefSeq; WP_062545128.1; NZ_CP012643.1.
DR AlphaFoldDB; A0A0P0CST0; -.
DR STRING; 512763.DC20_18165; -.
DR KEGG; rti:DC20_18165; -.
DR PATRIC; fig|512763.3.peg.3994; -.
DR OrthoDB; 9771883at2; -.
DR Proteomes; UP000061382; Chromosome.
DR GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0044248; P:cellular catabolic process; IEA:UniProt.
DR GO; GO:0006631; P:fatty acid metabolic process; IEA:InterPro.
DR GO; GO:1901575; P:organic substance catabolic process; IEA:UniProt.
DR Gene3D; 1.10.1040.50; -; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR006180; 3-OHacyl-CoA_DH_CS.
DR InterPro; IPR006176; 3-OHacyl-CoA_DH_NAD-bd.
DR InterPro; IPR006108; 3HC_DH_C.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR48075; 3-HYDROXYACYL-COA DEHYDROGENASE FAMILY PROTEIN; 1.
DR PANTHER; PTHR48075:SF5; 3-HYDROXYACYL-COA DEHYDROGENASE FAMILY PROTEIN; 1.
DR Pfam; PF00725; 3HCDH; 2.
DR Pfam; PF02737; 3HCDH_N; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 2.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00067; 3HCDH; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000061382}.
FT DOMAIN 3..181
FT /note="3-hydroxyacyl-CoA dehydrogenase NAD binding"
FT /evidence="ECO:0000259|Pfam:PF02737"
FT DOMAIN 183..280
FT /note="3-hydroxyacyl-CoA dehydrogenase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00725"
FT DOMAIN 299..382
FT /note="3-hydroxyacyl-CoA dehydrogenase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00725"
SQ SEQUENCE 383 AA; 42777 MW; E3BCC2F00855BCCD CRC64;
MIVGIIGSGA MGSGIAQVIA TAGHKVHVLD KNTQALARAS TQIKDSLRKL SAKGKISENE
ASEILDRLNF TEAHQDFGNC DLVLEAVVED LEVKQNLFRE VEMIVGEECI LASNTSSLSI
ASIASACEKP ERFIGIHFFN PAPLMPLVEI IPAVQTRDGL AEEIKRLVHS WGKMPVIAKD
TPGFIVNRVA RPFYGEAIRL LEEGIADVPT IDWAMTELGG FKMGPFTLMD FIGHDVNYRV
TESVFQSFFY DPRYKPSFTQ KRLFEAGYFG RKTGRGFYDY REGVVPPEPT KDEELGNVIL
NRILVMLINE AVDALALNVA SKEDLELAMT KGVNYPQGLL AWADELGQEK VLETLDTLYK
EYHEDRYRAS PLLRKMVRVN KLF
//
