ID A0A0P0LUI0_9BURK Unreviewed; 1072 AA.
AC A0A0P0LUI0;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=3-chloro-4-hydroxyphenylacetate reductive dehalogenase {ECO:0000313|EMBL:ALK89841.1};
DE EC=3.8.1.- {ECO:0000313|EMBL:ALK89841.1};
GN Name=cprA {ECO:0000313|EMBL:ALK89841.1};
GN ORFNames=L63ED372_02642 {ECO:0000313|EMBL:ALK89841.1};
OS Limnohabitans sp. 63ED37-2.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Limnohabitans.
OX NCBI_TaxID=1678128 {ECO:0000313|EMBL:ALK89841.1, ECO:0000313|Proteomes:UP000059510};
RN [1] {ECO:0000313|EMBL:ALK89841.1, ECO:0000313|Proteomes:UP000059510}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=63ED37-2 {ECO:0000313|EMBL:ALK89841.1,
RC ECO:0000313|Proteomes:UP000059510};
RA Ahn J.-H., Kim S.B.;
RT "Limnohabitans sp. 2 strains.";
RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP011774; ALK89841.1; -; Genomic_DNA.
DR RefSeq; WP_062406449.1; NZ_CP011774.1.
DR AlphaFoldDB; A0A0P0LUI0; -.
DR STRING; 1678128.L63ED372_02642; -.
DR KEGG; lih:L63ED372_02642; -.
DR PATRIC; fig|1678128.3.peg.2637; -.
DR OrthoDB; 370747at2; -.
DR Proteomes; UP000059510; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR CDD; cd00207; fer2; 1.
DR CDD; cd06185; PDR_like; 1.
DR Gene3D; 3.10.20.30; -; 1.
DR Gene3D; 3.30.70.20; -; 1.
DR Gene3D; 3.40.50.80; Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR InterPro; IPR036010; 2Fe-2S_ferredoxin-like_sf.
DR InterPro; IPR001041; 2Fe-2S_ferredoxin-type.
DR InterPro; IPR006058; 2Fe2S_fd_BS.
DR InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR InterPro; IPR012675; Beta-grasp_dom_sf.
DR InterPro; IPR017927; FAD-bd_FR_type.
DR InterPro; IPR039261; FNR_nucleotide-bd.
DR InterPro; IPR028894; RDH_dom.
DR InterPro; IPR017938; Riboflavin_synthase-like_b-brl.
DR PANTHER; PTHR47354:SF1; CARNITINE MONOOXYGENASE REDUCTASE SUBUNIT; 1.
DR PANTHER; PTHR47354; NADH OXIDOREDUCTASE HCR; 1.
DR Pfam; PF13486; Dehalogenase; 1.
DR Pfam; PF00111; Fer2; 1.
DR Pfam; PF13484; Fer4_16; 1.
DR PRINTS; PR00409; PHDIOXRDTASE.
DR SUPFAM; SSF54292; 2Fe-2S ferredoxin-like; 1.
DR SUPFAM; SSF54862; 4Fe-4S ferredoxins; 1.
DR SUPFAM; SSF52343; Ferredoxin reductase-like, C-terminal NADP-linked domain; 1.
DR SUPFAM; SSF63380; Riboflavin synthase domain-like; 1.
DR PROSITE; PS00197; 2FE2S_FER_1; 1.
DR PROSITE; PS00198; 4FE4S_FER_1; 1.
DR PROSITE; PS51379; 4FE4S_FER_2; 1.
DR PROSITE; PS51384; FAD_FR; 1.
PE 4: Predicted;
KW 2Fe-2S {ECO:0000256|ARBA:ARBA00022714};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Hydrolase {ECO:0000313|EMBL:ALK89841.1};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000059510};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 543..573
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
FT DOMAIN 750..855
FT /note="FAD-binding FR-type"
FT /evidence="ECO:0000259|PROSITE:PS51384"
SQ SEQUENCE 1072 AA; 117747 MW; D68EA239A8B6B5B2 CRC64;
MRLFSYRDRP VHLGPYPMER LRRTHAKPDD SALPTMQTLR FEHEDPESLA HAMARYMAMF
DLVRDGAVNP QMGEIPAEPD ERARHLKAAG YYFDASMMGI CALPASAWLA EPIRNPAVPA
LGEELAQSQP ASFAAGMDMI LADVLESART VHGPIAHHSH AIVILVEFAR DPQPGEPGCD
WLAGTQEPRA AVLAAQTAVL LSSYLRMLGY EARAHSASCS DVDLARLALA AGLTLPDGGN
PYVGQRYALA AVSTTLALAP DQALDPQQNR WQSHGPAWWL GQGTFKGAFH RDAYARREFR
QGAHPFETLK RQDTPTTFID HDRVPRFPKR ADFFARALFG DLGKSVQDDA KNAHYVMKSP
IGACARRALG ALLLLQFGPA RGPVAASTLD PQRNADKLKA ASYYLGVDAV GLCAVPEWAY
YSHDAGGNPM PAYHANALNL LIDQGHETME GASGDDWISV AQSMRAYLRF SLMGGILAEQ
IRRLGYSARV HSVLDGDVLQ PPLLLLSGLG EVSRIGEVIL NPFLGPRLKS GSVTTDMPMA
PDRPIDFGLQ SFCESCNKCA RECPSGAITA GPKLMYNGYE IWKSDAEKCA RYRITNAAGG
MCGRCMKTCP WNLEGLLADS LWRQVAMKLP AAAPALARLD DLLDRGSINP VKKWWWDIEL
DKRTGRYVQA AQTHQRTLQK DLDLRYEDQT LAVYPADKMP PPYPVTYPVN REEGIARYQA
LLTPAQYQAR LAAGQTEGLA PGPQPLPAEP PVFPVVLHKR EEMAEGLARY EFKAPDGREL
PPFTAGGHID VVIAPEYQRP YSLAGDPADR SRYVLGVLRE PPESGGRGGS ALMHRAFREG
RRVFVSRPVN HFALHEDATH SWLMAGGIGV TPMIAMAHRL YALGKPFDFH YSAASRKTAG
FLKDLAQAPW GHQVQYHFKD EGQRADLMQL LPNYAPGQHV YTCGAPRFMD GVFEAATVHG
WPEDALHREY FSVPEADAWV NQPFELLLQK SGRRLQVPAE RSATEVLAEA GVGVSVKCSD
GLCGVCALPY DAQASDAVEH RDFVLSQKER QQKIILCCSR AQHAGGVITL NL
//
