ID A0A0P0MAE4_9BURK Unreviewed; 776 AA.
AC A0A0P0MAE4;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN Name=luxQ {ECO:0000313|EMBL:ALK89454.1};
GN ORFNames=L63ED372_02251 {ECO:0000313|EMBL:ALK89454.1};
OS Limnohabitans sp. 63ED37-2.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Limnohabitans.
OX NCBI_TaxID=1678128 {ECO:0000313|EMBL:ALK89454.1, ECO:0000313|Proteomes:UP000059510};
RN [1] {ECO:0000313|EMBL:ALK89454.1, ECO:0000313|Proteomes:UP000059510}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=63ED37-2 {ECO:0000313|EMBL:ALK89454.1,
RC ECO:0000313|Proteomes:UP000059510};
RA Ahn J.-H., Kim S.B.;
RT "Limnohabitans sp. 2 strains.";
RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; CP011774; ALK89454.1; -; Genomic_DNA.
DR RefSeq; WP_062406026.1; NZ_CP011774.1.
DR AlphaFoldDB; A0A0P0MAE4; -.
DR STRING; 1678128.L63ED372_02251; -.
DR KEGG; lih:L63ED372_02251; -.
DR PATRIC; fig|1678128.3.peg.2240; -.
DR OrthoDB; 5519028at2; -.
DR Proteomes; UP000059510; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd16922; HATPase_EvgS-ArcB-TorS-like; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 1.
DR CDD; cd17546; REC_hyHK_CKI1_RcsC-like; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR InterPro; IPR021796; Tll0287-like.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR45339; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J; 1.
DR PANTHER; PTHR45339:SF6; RESPONSE REGULATORY DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF11845; DUF3365; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF00989; PAS; 1.
DR Pfam; PF00072; Response_reg; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00091; PAS; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Kinase {ECO:0000313|EMBL:ALK89454.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Reference proteome {ECO:0000313|Proteomes:UP000059510};
KW Transferase {ECO:0000313|EMBL:ALK89454.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 191..209
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 250..305
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 318..377
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 395..617
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 646..764
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT COILED 226..253
FT /evidence="ECO:0000256|SAM:Coils"
FT MOD_RES 695
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 776 AA; 87345 MW; A06D2EE587952456 CRC64;
MWVVLYTYQA SERMVRQYAT ESAQAHAVSL TQFRNFYTDE IVPRAMEAGV HVTHDYKNRK
NALPLPATLT LDLGHYLSKV DGGTQVRLYS EKPFPWRVQE RQLDDFQRQA LKHLKEKPDE
PFVREEILNG ERVLRYAQAD RMTLRCVACH NSYPSSPRTD WKTGDVRGAL EVVLPVSQWQ
ITSTGILNRT FVVLLALLFL GLLLVWLTVR RFREALLTSR ELSTERRAAI EQLSEEINER
KQIERQMRLS ESKLHSIFKS VPEAIVVADA HGLIVQCNAA TQAIFGYTPE ELIGQKVDRL
MGPKDGQRHD DYMLTYQRTG EKKIINQPRV LHGRRKDGQL FSLRLTISEM RVDDEVHFVG
VMQDFTAIEN AQRMLIEAKE KAEQDNRMRG EFLANMSHEI RTPMNGIVGM TELAMDTQDR
SAQKEYLTLA RDSANHLLHI INQILDFSKI EAQALELELL KVSPAQLIRD TSRSLEQLAR
VKDIDLQVDI SSAVPEWAWM DPVRMRQVLT NLIGNAIKFT EVGAVTVAVQ ALAGQDDDHC
VLRISITDTG IGFDPARTAA LFSPFTQGDG SVTRSFGGTG LGLAITRRLV HLMGGEISAN
GQPDLGACFT VTLPVEKTSL EVDDPSTPDG QASDLSLRPV YQKPISVLLV EDHDINRKLA
EIMLQRMGYR YVSACDGLQA LDVLEKDRFD VVLMDVMMPV MDGITALKLL REREAEQGQR
TRVLMVTAHA MTGDRERFLG AGADGYVSKP MSQAALQKEM ERVLNVPHAA NSDAAD
//
