ID A0A0P0MHJ7_9BURK Unreviewed; 496 AA.
AC A0A0P0MHJ7;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE SubName: Full=Uric acid transporter UacT {ECO:0000313|EMBL:ALK92340.1};
GN Name=uacT {ECO:0000313|EMBL:ALK92340.1};
GN ORFNames=L103DPR2_01945 {ECO:0000313|EMBL:ALK92340.1};
OS Limnohabitans sp. 103DPR2.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Limnohabitans.
OX NCBI_TaxID=1678129 {ECO:0000313|EMBL:ALK92340.1, ECO:0000313|Proteomes:UP000063254};
RN [1] {ECO:0000313|EMBL:ALK92340.1, ECO:0000313|Proteomes:UP000063254}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=103DPR2 {ECO:0000313|EMBL:ALK92340.1,
RC ECO:0000313|Proteomes:UP000063254};
RA Ahn J.-H., Kim S.B.;
RT "Limnohabitans sp. 2 strains.";
RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. {ECO:0000256|ARBA:ARBA00008821}.
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DR EMBL; CP011834; ALK92340.1; -; Genomic_DNA.
DR RefSeq; WP_055360905.1; NZ_CP011834.1.
DR AlphaFoldDB; A0A0P0MHJ7; -.
DR STRING; 1678129.L103DPR2_01945; -.
DR KEGG; lim:L103DPR2_01945; -.
DR PATRIC; fig|1678129.3.peg.1938; -.
DR OrthoDB; 9805749at2; -.
DR Proteomes; UP000063254; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:UniProt.
DR InterPro; IPR006043; NCS2.
DR InterPro; IPR006042; Xan_ur_permease.
DR NCBIfam; TIGR00801; ncs2; 1.
DR NCBIfam; NF037981; NCS2_1; 1.
DR PANTHER; PTHR42810; PURINE PERMEASE C1399.01C-RELATED; 1.
DR PANTHER; PTHR42810:SF4; URIC ACID TRANSPORTER UACT; 1.
DR Pfam; PF00860; Xan_ur_permease; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000063254};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 20..40
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 52..71
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 77..98
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 110..129
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 135..153
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 213..233
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 239..258
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 292..312
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 362..381
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 393..415
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 427..446
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 458..476
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 496 AA; 51686 MW; 0AFB6861ECD83A75 CRC64;
MTTVSLHPVD EKLPTGKLAA LGLQHVLVMY AGAVAVPLIV GRALKLSPQD VAYLISADLF
CCGLVTLIQS LGATQWFGIR LPVMMGVTFA SVAPMVAMAN ANPGEMGAQL IFGAIIGAGV
ISILIAPVVS RMLRFFPPVV TGTIIAVIGI SLMRIGINWI FGNPVGPTAP SIVNPEHKQW
LDAAAAAASA PGSTLPAIPK DLALLPKMPN PKYADLTGVG IAGLVLVTIM LISKYAKGFV
ANISVLLGIV VGGVVAAAMG LMNFDKVGKA AWFDVVMPFH FGAPVFEPVL ILTMTLVMIV
VMIESTGMFL ALGEMTDKKV DQAALTRGLR TDGLGTLLGG IFNTFPYTSF SQNVGLVAVT
GVKSRFVCVA GGLILLALGL LPKMAALIES LPTVVLGGAG LVMFGMVAAT GIRILSNVDF
KNNSYNAMIV AISIGIGMIP LIAPNFKQWM PHNLHPLIES GILLASISAV LLNLFFNGAN
GDTRDAVEAA KQVDSH
//
