ID A0A0P0P3R0_9CAUL Unreviewed; 896 AA.
AC A0A0P0P3R0;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=AQ619_16875 {ECO:0000313|EMBL:ALL14903.1};
OS Caulobacter henricii.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Caulobacterales;
OC Caulobacteraceae; Caulobacter.
OX NCBI_TaxID=69395 {ECO:0000313|EMBL:ALL14903.1, ECO:0000313|Proteomes:UP000056905};
RN [1] {ECO:0000313|EMBL:ALL14903.1, ECO:0000313|Proteomes:UP000056905}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CB4 {ECO:0000313|EMBL:ALL14903.1,
RC ECO:0000313|Proteomes:UP000056905};
RA Scott D., Ely B.;
RT "Conservation of the essential genome among Caulobacter and Brevundimonas
RT species.";
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; CP013002; ALL14903.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0P0P3R0; -.
DR STRING; 69395.AQ619_16875; -.
DR KEGG; chq:AQ619_16875; -.
DR OrthoDB; 9806130at2; -.
DR Proteomes; UP000056905; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00075; HATPase; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd01987; USP_OKCHK; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 1.20.120.620; Backbone structure of the membrane domain of e. Coli histidine kinase receptor kdpd; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR038318; KdpD_sf.
DR InterPro; IPR025201; KdpD_TM.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR003852; Sig_transdc_His_kinase_KdpD_N.
DR PANTHER; PTHR45569; SENSOR PROTEIN KDPD; 1.
DR PANTHER; PTHR45569:SF1; SENSOR PROTEIN KDPD; 1.
DR Pfam; PF13493; DUF4118; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF02702; KdpD; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF52402; Adenine nucleotide alpha hydrolases-like; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:ALL14903.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000056905};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 400..420
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 432..459
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 479..499
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 671..889
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 896 AA; 96267 MW; A067CF985034769B CRC64;
MPVDERGYSD GRPDPEALLA AANRASRGRL KVFLGMAPGV GKTYEMLRAA RRRKAKGDDV
VVGLVETHGR RETESLLRDM EVMPRKPMDH RDRVVMEFDL DGALARKPQL LLVDEYAHSN
ASGSRHPKRW QDVEELLAAG IDVWTTLNVQ HLESLVDVVL RITGVRQRET VPDRALSRAD
DIEVVDITPD ELRERMAAGK VYVPETARLA SENFFKVENL TALRELALRR AAQTVDDQLI
ATLREKGVEG PWAAGERILV LVGGDAMAGG LVRTGRRLSD MMMDAPWTVA HVDRPDQTPP
GPAAAARAND ALKLAEQLGG ATVVLSGADV VATVMAYARR NNVTQIVIGK SADSRWRDLM
GKSLAAALLR KARGAAIHVV TEAAHEPVQE IPRPRGPTPW LAYLTGAAFV GVATLVAWGL
DVAFDRVDLG MIFLAAVLAA GVLHGLKPAL AAATAAFLVY NYLFLEPRYS FQVGSPTDFL
TLIVFWAVAL AAGGLAGRVR DQGRDAQRRA SAVSALLAAS RTFSAAAGRE AAAGAIAEQA
AAAAGAKAMV LLPRDGELQP AAGAPTLESL DAAPMAAARW AWEKGEPAGF GTGTLPQTRW
TFWPLDGVRS RAGVAGVEAG AMVSGSDTER LVLALLEQGA VALERAELAG EAVEAETLRR
ADRFRSALLN SISHDLRTPL STVLGASSTL IDYGKTLTPA VRDDLTLSIR EEAERLNRYV
GNLLDMTRLE GGALRLRTDW TDVRDVLGAA ADRVTRRLGG RDLTRDYPAE LSLVRVDGSL
LEQAIVNILE NAIAYSPDGA RIEMAAYEDR ANVVISIEDE GRGIPTAELE RVFEKFRRME
EPSDRSQGAG LGLSIAKGFI DAMGGRIAAA SPIHDGQGTR ILISLPKAIA TPHHLL
//
