ID A0A0P0SGX7_9PSEU Unreviewed; 265 AA.
AC A0A0P0SGX7;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 35.
DE SubName: Full=IclR family transcriptional regulator {ECO:0000313|EMBL:ALL83654.1};
GN ORFNames=AD017_25085 {ECO:0000313|EMBL:ALL83654.1};
OS Pseudonocardia sp. EC080619-01.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Pseudonocardia.
OX NCBI_TaxID=1096856 {ECO:0000313|EMBL:ALL83654.1, ECO:0000313|Proteomes:UP000066228};
RN [1] {ECO:0000313|EMBL:ALL83654.1, ECO:0000313|Proteomes:UP000066228}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EC080619-01 {ECO:0000313|EMBL:ALL83654.1,
RC ECO:0000313|Proteomes:UP000066228};
RX PubMed=26535611; DOI=10.1021/jacs.5b09794;
RA Van Arnam E.B., Sit C.S.;
RT "A Rebeccamycin Analog Provides Plasmid-Encoded Niche Defense.";
RL J. Am. Chem. Soc. 137:14272-14274(2015).
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DR EMBL; CP012184; ALL83654.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0P0SGX7; -.
DR STRING; 1096856.AD017_25085; -.
DR KEGG; pecq:AD017_25085; -.
DR PATRIC; fig|1096856.3.peg.5290; -.
DR Proteomes; UP000066228; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR014757; Tscrpt_reg_IclR_C.
DR InterPro; IPR005471; Tscrpt_reg_IclR_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30136; HELIX-TURN-HELIX TRANSCRIPTIONAL REGULATOR, ICLR FAMILY; 1.
DR PANTHER; PTHR30136:SF24; HTH-TYPE TRANSCRIPTIONAL REPRESSOR ALLR; 1.
DR Pfam; PF09339; HTH_IclR; 1.
DR Pfam; PF01614; IclR; 1.
DR SMART; SM00346; HTH_ICLR; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51077; HTH_ICLR; 1.
DR PROSITE; PS51078; ICLR_ED; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000066228};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 20..80
FT /note="HTH iclR-type"
FT /evidence="ECO:0000259|PROSITE:PS51077"
FT DOMAIN 81..263
FT /note="IclR-ED"
FT /evidence="ECO:0000259|PROSITE:PS51078"
SQ SEQUENCE 265 AA; 28306 MW; BB539C2524A40E29 CRC64;
MDRRWDRNHS SVRGQAVAAT NSVVSAVRVI EAVGQRQPIG LSDLARAVGL PKSTVQRTLL
TLAEVGWCTT DDVSRWRLTY RAFAVGNQAR DAGGLRDRAL PVLHELQLVT GETIHLAAPD
GRDLVLIERL DTAHRLRAFL PLGHRIPLHA SATGQAYLAA CPDAEIDAYL QGPLPPSTRF
TVTDPDTLRD RLAGVRERGW SVNPEGLSDG IAAVGAAIVG TDGRPVGSLS VSGPTVRMTA
DVFDDHGRAA VDAARRISRE LGAPG
//
