ID A0A0P1GD25_9RHOB Unreviewed; 1393 AA.
AC A0A0P1GD25;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Cyclic di-GMP phosphodiesterase Gmr {ECO:0000313|EMBL:CUH79247.1};
DE EC=3.1.4.52 {ECO:0000313|EMBL:CUH79247.1};
GN Name=gmr_2 {ECO:0000313|EMBL:CUH79247.1};
GN ORFNames=TRN7648_02372 {ECO:0000313|EMBL:CUH79247.1};
OS Tropicibacter naphthalenivorans.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Tropicibacter.
OX NCBI_TaxID=441103 {ECO:0000313|EMBL:CUH79247.1, ECO:0000313|Proteomes:UP000054935};
RN [1] {ECO:0000313|EMBL:CUH79247.1, ECO:0000313|Proteomes:UP000054935}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CECT 7648 {ECO:0000313|EMBL:CUH79247.1,
RC ECO:0000313|Proteomes:UP000054935};
RG Swine Surveillance;
RL Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CYSE01000004; CUH79247.1; -; Genomic_DNA.
DR STRING; 441103.TRN7648_02372; -.
DR Proteomes; UP000054935; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0071111; F:cyclic-guanylate-specific phosphodiesterase activity; IEA:UniProtKB-EC.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd00130; PAS; 2.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 3.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 2.
DR PANTHER; PTHR44757:SF11; DIGUANYLATE CYCLASE DGCE-RELATED; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF13426; PAS_9; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00091; PAS; 3.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 3.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:CUH79247.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054935};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..45
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 51..73
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 85..105
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 125..147
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 159..184
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 190..208
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 228..249
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 255..274
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 327..360
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 366..384
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 391..412
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 432..454
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 466..485
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 505..522
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 534..566
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 865..895
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 992..1124
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 1133..1386
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 1393 AA; 151155 MW; 0787913EE001A7C5 CRC64;
MRHHRIDTSV RGFEREAVFR PTPFLGLALF IVVQACGLLL VLPGFESWGG LYAMHPVTLG
LGVLLTAAIV LALPEMPSGI WRKIAVGIGA FTLVSGLSLL TFRWLELQSL APAAVLDRIG
TAKAARHVSV ATLVMIVGLS LAALFQAQAW ARPRHRARFV TASLGLIFLI GLTSALQLAG
YLLAPSKDTL IHGMGAPTAV LFLTQALAMC DHPTVRTPVR GKGFALRVLP TIIGASLASL
HGAVALSMGR PVLETTLFVG LLYGLVTLLA VRVLRQRGAA TLSAIVAVSG HRPRQSELYF
PSLVALELWA LFRAGQRGQR IHDFIMIFTL AVGAIALDAA STTIAGVWWA NFALIFLVLF
RPLRDWPLIA LTGLTAMVAA NTLMGHSLWP TVVMSTINSM TAVLSAAFLH RLLLPKTDGN
GWQCLRLTAP RLVMAILGLG VVVMIMGTVS SAFLAKTFET QMSAIWVFWV VSDFVGGLAV
AGIAIGLALQ SNAPDVPHVA RPRTAVLHMA FAAAAAACGF ALGTQNPTLH DMAIFGIVVI
ALAATFHATL IDGAVSVFVA VIAFFLSAAL AQAPEDSFPW TAVLFGETAF LLRSFAKHRE
AQSTATQVAM FERGPIMMAT YDSDQRIVSA SNRLADFVGS TASALVGKPI FGESVLFLPE
EERLRAEVFH ACPTDEILIV NGTLRTHDGQ EKPVIVESRW SDGPTLPFRF TAQFTDVSDF
ASFEFANVLL SKTDAIIMVQ GPDKRVRAVS EAWVRATGYS MEESIGVDPS IWLMDETAIE
EIREQRNRPG YPACDGGTGW RRVLRAKDGR RLVFIASGAS QTVAGETLLI MTLVDVTALE
KQHEAQLQYL SESPAASIVQ GEHYRIISVS EGFKRLTGYS DDDLIGNDGQ ILLPETCRAE
VVANRGQSHP LGVVRTDVRQ IICKDGREIT MRRDALNTRS VTSGEILVIS AMTDLSAELE
VRQTLEEMAL RDPLTGLYVR RYLTMPDSLP TDDCCLIALD IDHFKSVNDS FGHDVGDRLL
VKVADALKAV LPNAGVALRT GGEEFCIWAP WLGWRVAEAF AETLREAIAD VVITTPGGHI
GRTASIGVAH WQAGESFDRA FQTCDTALRA AKENGRDRVV LADHTFKEAI GSSNATLADI
EAALRADDIV YHLQPVIDCA RNRTIGYEAL VRWDRGDAGN MGPASFLGGY LELTSQKQWL
DYPIKALVSA CHALPPEDDG FLAVNLAVSA VAYDGAARHL ARLLAPISQK RKIVLEISEQ
SMSHRLEVDA LRRELLLLKD AGFEIALDDF GREASNLDRL LDLPISWLKL DRCLIARSDV
DQRAQELLRH MPDICKAFDA EIIAEGVETA IQRDTLIGLG ITIQQGYLHG RPAPAAEWKQ
NTIPFRRQSL SAI
//
