ID A0A0P1IJN3_9RHOB Unreviewed; 329 AA.
AC A0A0P1IJN3;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE RecName: Full=siroheme decarboxylase {ECO:0000256|ARBA:ARBA00023471};
DE EC=4.1.1.111 {ECO:0000256|ARBA:ARBA00023471};
GN ORFNames=RUE5091_04133 {ECO:0000313|EMBL:CUK17535.1};
OS Ruegeria denitrificans.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Ruegeria.
OX NCBI_TaxID=1715692 {ECO:0000313|EMBL:CUK17535.1, ECO:0000313|Proteomes:UP000051260};
RN [1] {ECO:0000313|EMBL:CUK17535.1, ECO:0000313|Proteomes:UP000051260}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CECT 5091 {ECO:0000313|EMBL:CUK17535.1,
RC ECO:0000313|Proteomes:UP000051260};
RG Swine Surveillance;
RL Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=2 H(+) + siroheme = 12,18-didecarboxysiroheme + 2 CO2;
CC Xref=Rhea:RHEA:19093, ChEBI:CHEBI:15378, ChEBI:CHEBI:16526,
CC ChEBI:CHEBI:60052, ChEBI:CHEBI:140497; EC=4.1.1.111;
CC Evidence={ECO:0000256|ARBA:ARBA00023409};
CC -!- PATHWAY: Porphyrin-containing compound metabolism.
CC {ECO:0000256|ARBA:ARBA00023444}.
CC -!- SIMILARITY: Belongs to the Ahb/Nir family.
CC {ECO:0000256|ARBA:ARBA00023457}.
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DR EMBL; CYUD01000017; CUK17535.1; -; Genomic_DNA.
DR RefSeq; WP_058283749.1; NZ_CYUD01000017.1.
DR AlphaFoldDB; A0A0P1IJN3; -.
DR STRING; 1715692.RUE5091_04133; -.
DR OrthoDB; 9806536at2; -.
DR Proteomes; UP000051260; Unassembled WGS sequence.
DR GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR Gene3D; 3.30.70.3460; -; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000485; AsnC-type_HTH_dom.
DR InterPro; IPR040523; AsnC_trans_reg2.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR43413:SF1; SIROHEME DECARBOXYLASE NIRL SUBUNIT; 1.
DR PANTHER; PTHR43413; TRANSCRIPTIONAL REGULATOR, ASNC FAMILY; 1.
DR Pfam; PF17805; AsnC_trans_reg2; 2.
DR Pfam; PF13404; HTH_AsnC-type; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000256|ARBA:ARBA00023239}.
FT DOMAIN 6..49
FT /note="HTH asnC-type"
FT /evidence="ECO:0000259|Pfam:PF13404"
FT DOMAIN 67..135
FT /note="Siroheme decarboxylase AsnC-like ligand binding"
FT /evidence="ECO:0000259|Pfam:PF17805"
FT DOMAIN 229..316
FT /note="Siroheme decarboxylase AsnC-like ligand binding"
FT /evidence="ECO:0000259|Pfam:PF17805"
SQ SEQUENCE 329 AA; 36187 MW; FF4E8667C45D075D CRC64;
MEHITDPIDR RLLDEFQRDF PVTDHPFQVL GHILGLDETE VIDRLTRMRA TGRITRVGAT
IAPGAVSAST LAAVAAPEEQ LEEIAALIDA EPGVNHNYQR EDTWNLWFVA TGPDRAHVSD
TLARIGQRTR LRVLDLRLVR PFNIDLGFRM SGDTRNVPGP RKVNRAALQD GDRALLQALS
SGLQLVTDPY AALARSLNRP PPEALERIDA LHDAGIISRL GVIVRHRALG WSANAMVVWD
MPADQVGTAG PALAAHPGVT LCYERNPVED VWPYRLYSMI HARSRNEALE ILSGAIALPE
LAGARHKVLF STRCFKQTGA LIQPKEAAA
//
