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Database: UniProt
Entry: A0A0P1IR91_9RHOB
LinkDB: A0A0P1IR91_9RHOB
Original site: A0A0P1IR91_9RHOB 
ID   A0A0P1IR91_9RHOB        Unreviewed;       464 AA.
AC   A0A0P1IR91;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   25-OCT-2017, entry version 16.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377,
GN   ECO:0000313|EMBL:CUK24341.1};
GN   ORFNames=TA5114_00124 {ECO:0000313|EMBL:CUK24341.1};
OS   Thalassobius sp. CECT 5114.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhodobacterales;
OC   Rhodobacteraceae; Thalassobius.
OX   NCBI_TaxID=1715690 {ECO:0000313|EMBL:CUK24341.1, ECO:0000313|Proteomes:UP000051184};
RN   [1] {ECO:0000313|EMBL:CUK24341.1, ECO:0000313|Proteomes:UP000051184}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CECT 5114 {ECO:0000313|EMBL:CUK24341.1,
RC   ECO:0000313|Proteomes:UP000051184};
RG   Swine Surveillance;
RL   Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00911680}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
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DR   EMBL; CYUE01000002; CUK24341.1; -; Genomic_DNA.
DR   RefSeq; WP_058313363.1; NZ_CYUE01000002.1.
DR   EnsemblBacteria; CUK24341; CUK24341; TA5114_00124.
DR   Proteomes; UP000051184; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747950};
KW   Complete proteome {ECO:0000313|Proteomes:UP000051184};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00911664};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00747996};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00911684};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747895};
KW   Reference proteome {ECO:0000313|Proteomes:UP000051184}.
FT   DOMAIN      156    286       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      372    441       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     164    171       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   464 AA;  51953 MW;  4617603A9DF1FB61 CRC64;
     MTQEQWGSLQ QDLLKTVGQN NYKAWIEPLR LTELANGVAT FTVPTNFIGN YVSQNFGDLI
     IHQLSQAGED VQRVHFTVGR AAANSNGAAS PSIAAPGKPS ANRASAPATS TVASSKDDLP
     GAPLDTRFTF DSFVVGKPNE LANAAARRVA EGGPVSFNPL FLYGGVGLGK THLMHAIAWE
     LQTQRPDLNV LYLSAEQFMY RFVQALRDRK MMDFKEMFRS VDVLMVDDVQ FIAGKDSTQE
     EFFHTFNALV DQNKQIIISA DRAPGEIKDM EDRIRSRLQC GLVVDLHPTD YELRLGILQS
     KVEQYRGQYP DLKIADGVLE FLAHRISTNV RVLEGALTRL FAFASLVGRE ITMDLTQDCL
     SDVLRASERK ISVEEIQRRV AEHYNIRLSD MIGPKRVRTF ARPRQVAMFL CKQLTSRSLP
     EIGRRFGGRD HTTVMHGVRR IEELRSSDGQ IAEDLELLRR ALEA
//
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