ID   A0A0P6XK62_9CHLR        Unreviewed;       936 AA.
AC   A0A0P6XK62;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   24-JAN-2024, entry version 20.
DE   RecName: Full=beta-N-acetylhexosaminidase {ECO:0000256|ARBA:ARBA00012663};
DE            EC=3.2.1.52 {ECO:0000256|ARBA:ARBA00012663};
GN   ORFNames=ADM99_10470 {ECO:0000313|EMBL:KPL71837.1};
OS   Leptolinea tardivitalis.
OC   Bacteria; Chloroflexota; Anaerolineae; Anaerolineales; Anaerolineaceae;
OC   Leptolinea.
OX   NCBI_TaxID=229920 {ECO:0000313|EMBL:KPL71837.1, ECO:0000313|Proteomes:UP000050430};
RN   [1] {ECO:0000313|EMBL:KPL71837.1, ECO:0000313|Proteomes:UP000050430}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YMTK-2 {ECO:0000313|EMBL:KPL71837.1,
RC   ECO:0000313|Proteomes:UP000050430};
RA   Hemp J., Ward L.M., Pace L.A., Fischer W.W.;
RT   "Genome sequence of Leptolinea tardivitalis DSM 16556.";
RL   Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine
CC         residues in N-acetyl-beta-D-hexosaminides.; EC=3.2.1.52;
CC         Evidence={ECO:0000256|ARBA:ARBA00001231};
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 3 family.
CC       {ECO:0000256|ARBA:ARBA00005336}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KPL71837.1}.
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DR   EMBL; LGCK01000010; KPL71837.1; -; Genomic_DNA.
DR   RefSeq; WP_062420496.1; NZ_LGCK01000010.1.
DR   AlphaFoldDB; A0A0P6XK62; -.
DR   STRING; 229920.ADM99_10470; -.
DR   PATRIC; fig|229920.5.peg.2007; -.
DR   OrthoDB; 9805821at2; -.
DR   Proteomes; UP000050430; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 3.20.20.300; Glycoside hydrolase, family 3, N-terminal domain; 1.
DR   InterPro; IPR001764; Glyco_hydro_3_N.
DR   InterPro; IPR036962; Glyco_hydro_3_N_sf.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   PANTHER; PTHR30480:SF13; BETA-HEXOSAMINIDASE; 1.
DR   PANTHER; PTHR30480; BETA-HEXOSAMINIDASE-RELATED; 1.
DR   Pfam; PF00933; Glyco_hydro_3; 1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000050430};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        843..864
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        876..897
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        903..925
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          63..414
FT                   /note="Glycoside hydrolase family 3 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00933"
SQ   SEQUENCE   936 AA;  102208 MW;  F60904E850E079BF CRC64;
     MSPIKALKRT SKTGSVFTCI HRLVVIFFCL FNLFPLTTVF AEAPTPTANK IAAKNLLAKM
     TPEEKVGQLF LVTFKGTDTT TASQIYNLIV KRHIGGVMLS AENGNFPASE NPAKDAYQLI
     QILQKIRIDA ASADSSIDCI PLFIGISQEG DQFPNDQILS GLTPMPDAMS IGATWNPEMA
     RSVGAAFGDE LRRLGFNLYM GPSLDVLANV PSNGTEDLGV RTFGGDPYWV GEMGKEFIAG
     LHEGSDGRMV VISKHFPGRG GSDRPADEEV ATVRKSLEQL KQIELAPFFS STDLNNSPES
     ITDGFLVSHI RYQGFQGNIR ATTKPVSFDS AALSQLMALP QLQPWREAGG VLVSENLGSQ
     AIRKFFDPTG MSFDGRQIAR NALLAGNDML YVNNFISTGD KDAFDTLTKT MDFFTQKYRE
     DPAFAQRVNT SVERILSLKY KLYPKFDEKT ILLPEASISH LGEYEQVSFD VAQQAVTLIS
     PNEADLQNVL ARPPEMRERM VFLTDVVSGT QCQKCPEQVT MKVDSLQKAV LRLYGPQAGG
     QVSGARMSSY SFADLDQMLS GAANTETLSS EIREADWIVF SFQKISSDRP VSLAMKRLLS
     ERQDLVRNKK IVAFAFNAPY YLDSTDISKL TAYYALYSKI PSFIDVAARV LFQEIPAKGI
     PPVTVPGIGY DLIKATTPDS TQLISLTLDL PEIQNPIGGV QPPTTAPTQI PLFKVGDNLP
     VRTGIILDQN HHPVPDGTVT KFVFTLGDEK SIVQQVETVT KAGIAHASFR IQASGLLEVR
     AVCEPAMTSQ ILQLDVTGTE GAQVTAIAPT PLPTQTAAPE PTQEPTPTVV PTITAGEIRA
     RSFGGWLAGL MVLIGLIILF YQVTSHRISV RWGVRFALLT ALMGSFGLIV YGLTPIGKPL
     PEIWNALIFS GAGGLIGSLI AWIWYSYPRW FSEKPE
//