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Database: UniProt
Entry: A0A0P7ABW0_9SPHN
LinkDB: A0A0P7ABW0_9SPHN
Original site: A0A0P7ABW0_9SPHN 
ID   A0A0P7ABW0_9SPHN        Unreviewed;       484 AA.
AC   A0A0P7ABW0;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   27-SEP-2017, entry version 14.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=AAJ72_12630 {ECO:0000313|EMBL:KPM22009.1};
OS   Citromicrobium sp. RCC1885.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Sphingomonadales;
OC   Sphingomonadaceae; Citromicrobium.
OX   NCBI_TaxID=1647104 {ECO:0000313|EMBL:KPM22009.1, ECO:0000313|Proteomes:UP000050479};
RN   [1] {ECO:0000313|EMBL:KPM22009.1, ECO:0000313|Proteomes:UP000050479}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RCC1885 {ECO:0000313|EMBL:KPM22009.1,
RC   ECO:0000313|Proteomes:UP000050479};
RA   Zheng Q., Liu Y., Lin W., Jiao N.;
RT   "A comprehensive comparison of genomes of Citromicrobium spp.
RT   strains.";
RL   Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KPM22009.1}.
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DR   EMBL; LBLY01000004; KPM22009.1; -; Genomic_DNA.
DR   RefSeq; WP_010235898.1; NZ_LBLY01000004.1.
DR   EnsemblBacteria; KPM22009; KPM22009; AAJ72_12630.
DR   PATRIC; fig|1647104.3.peg.2616; -.
DR   Proteomes; UP000050479; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000050479};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000050479}.
FT   DOMAIN      180    308       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      392    461       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     188    195       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   484 AA;  54367 MW;  3D227B0F465F2464 CRC64;
     MARIPDTNGA ARKRAKGEGE DMERVALAAD WDDISTGLRK DLGHQLHSQW IKPIQLGEFD
     SETGTLALYL PSEFAAEWVR KHFADRLSLA WKIMRSEIKT VAIEVHPSRK RMADISLGDS
     RRPANDGPEL RVVSDGGFGD PGFSSVGLDA SLTFAAFVTG DANVLARNAA QRMAANEKPQ
     FSPLYIKAAT GQGKTHLLHA IGHQFLSQHP RARIFYCSAE RFMVEFVQAL KQNRMIEFKT
     RLRGFDLLLV DDLQFIIGKA SAQEELLYTI DHLLSEGKRL VFAADRAPQA LDSVEPRLLS
     RLSMGLVADI QPADLELRRS ILESKLTRFA PLSVPDDVVD FLARTITRNV RELVGGLNKL
     IAYAQLTGQP VSLQLAEEQL TDILSANRRR ITIDEIQRTV CQFYRIDRSE MSSKRRTRAV
     VRPRQVAMYL SKVLTPRSYP EIGRKFGGRD HSTVIHAVKL IEDLRTRDAD MDGDVRSLLR
     QLES
//
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