ID A0A0P7DUQ6_9GAMM Unreviewed; 225 AA.
AC A0A0P7DUQ6;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE RecName: Full=Ribosomal RNA small subunit methyltransferase D {ECO:0000256|PIRNR:PIRNR004553};
DE EC=2.1.1.171 {ECO:0000256|PIRNR:PIRNR004553};
GN ORFNames=AOG28_12000 {ECO:0000313|EMBL:KPM77706.1};
OS Cobetia sp. UCD-24C.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Halomonadaceae; Cobetia.
OX NCBI_TaxID=1716176 {ECO:0000313|EMBL:KPM77706.1, ECO:0000313|Proteomes:UP000050261};
RN [1] {ECO:0000313|EMBL:KPM77706.1, ECO:0000313|Proteomes:UP000050261}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UCD-24C {ECO:0000313|EMBL:KPM77706.1,
RC ECO:0000313|Proteomes:UP000050261};
RA Krusor M., Coil D.A., Lang J.M., Eisen J.A., Alexiev A.;
RT "Draft Genome of Cobetia sp. UCD-24C.";
RL Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Specifically methylates the guanine in position 966 of 16S
CC rRNA in the assembled 30S particle. {ECO:0000256|PIRNR:PIRNR004553}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=guanosine(966) in 16S rRNA + S-adenosyl-L-methionine = H(+) +
CC N(2)-methylguanosine(966) in 16S rRNA + S-adenosyl-L-homocysteine;
CC Xref=Rhea:RHEA:23548, Rhea:RHEA-COMP:10211, Rhea:RHEA-COMP:10212,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789,
CC ChEBI:CHEBI:74269, ChEBI:CHEBI:74481; EC=2.1.1.171;
CC Evidence={ECO:0000256|PIRNR:PIRNR004553};
CC -!- SIMILARITY: Belongs to the methyltransferase superfamily. RsmD family.
CC {ECO:0000256|PIRNR:PIRNR004553}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPM77706.1}.
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DR EMBL; LJTD01000007; KPM77706.1; -; Genomic_DNA.
DR RefSeq; WP_054556543.1; NZ_LJTD01000007.1.
DR AlphaFoldDB; A0A0P7DUQ6; -.
DR STRING; 1716176.AOG28_12000; -.
DR PATRIC; fig|1716176.3.peg.3196; -.
DR Proteomes; UP000050261; Unassembled WGS sequence.
DR GO; GO:0052913; F:16S rRNA (guanine(966)-N(2))-methyltransferase activity; IEA:UniProtKB-EC.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR004398; RNA_MeTrfase_RsmD.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR NCBIfam; TIGR00095; 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD; 1.
DR PANTHER; PTHR43542; METHYLTRANSFERASE; 1.
DR PANTHER; PTHR43542:SF1; METHYLTRANSFERASE; 1.
DR Pfam; PF03602; Cons_hypoth95; 1.
DR PIRSF; PIRSF004553; CHP00095; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|PIRNR:PIRNR004553,
KW ECO:0000313|EMBL:KPM77706.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000050261};
KW rRNA processing {ECO:0000256|PIRNR:PIRNR004553};
KW S-adenosyl-L-methionine {ECO:0000256|PIRNR:PIRNR004553};
KW Transferase {ECO:0000256|PIRNR:PIRNR004553, ECO:0000313|EMBL:KPM77706.1}.
FT REGION 1..38
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 9..23
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 225 AA; 24146 MW; D53F7B2ACEFE4BFF CRC64;
MKKRASSQGP ARGKSNAPSR ADKQSGKRGQ AAGGPGRLRI IGGRFKRRLL NVIDAPGLRP
TPDRVRETLY NWLGFHVGGA RVLDLYAGSG ALGLEALSRE AAHVTFVERD SRVARALEAN
LATLANGDSL PTQVVTGDVL HWLETATPAA GGMDLVLLDP PFRLELAAAS CALLEAHGWL
SDDAMIYLEV ESGLDPVVPA NWQLHRESRA GDSHGRLYRR HPPAA
//
