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Database: UniProt
Entry: A0A0P7WFX3_9TELE
LinkDB: A0A0P7WFX3_9TELE
Original site: A0A0P7WFX3_9TELE 
ID   A0A0P7WFX3_9TELE        Unreviewed;       485 AA.
AC   A0A0P7WFX3;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   25-OCT-2017, entry version 6.
DE   RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189};
DE   Flags: Fragment;
GN   ORFNames=Z043_119452 {ECO:0000313|EMBL:KPP62371.1};
OS   Scleropages formosus (Asian bonytongue).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Osteoglossocephala;
OC   Osteoglossomorpha; Osteoglossiformes; Osteoglossidae; Scleropages.
OX   NCBI_TaxID=113540 {ECO:0000313|EMBL:KPP62371.1, ECO:0000313|Proteomes:UP000034805};
RN   [1] {ECO:0000313|EMBL:KPP62371.1, ECO:0000313|Proteomes:UP000034805}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Aro1 {ECO:0000313|EMBL:KPP62371.1};
RA   Tan M.H., Gan H.M., Croft L.J., Austin C.M.;
RT   "The genome of the Asian arowana (Scleropages formosus).";
RL   Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Essential component of the vacuolar proton pump (V-
CC       ATPase), a multimeric enzyme that catalyzes the translocation of
CC       protons across the membranes. Required for assembly and activity
CC       of the V-ATPase. {ECO:0000256|RuleBase:RU361189}.
CC   -!- SIMILARITY: Belongs to the V-ATPase 116 kDa subunit family.
CC       {ECO:0000256|RuleBase:RU361189}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KPP62371.1}.
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DR   EMBL; JARO02008753; KPP62371.1; -; Genomic_DNA.
DR   Proteomes; UP000034805; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0033179; C:proton-transporting V-type ATPase, V0 domain; IEA:InterPro.
DR   GO; GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
DR   InterPro; IPR002490; V-ATPase_116kDa_su.
DR   PANTHER; PTHR11629; PTHR11629; 2.
DR   Pfam; PF01496; V_ATPase_I; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000034805};
KW   Hydrogen ion transport {ECO:0000256|RuleBase:RU361189};
KW   Ion transport {ECO:0000256|RuleBase:RU361189};
KW   Membrane {ECO:0000256|RuleBase:RU361189};
KW   Reference proteome {ECO:0000313|Proteomes:UP000034805};
KW   Transmembrane {ECO:0000256|RuleBase:RU361189};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU361189};
KW   Transport {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    145    169       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    189    208       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    288    309       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    315    339       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    380    404       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   NON_TER     485    485       {ECO:0000313|EMBL:KPP62371.1}.
SQ   SEQUENCE   485 AA;  54811 MW;  B156A4A798D8310A CRC64;
     MAAGVNTRID DLQMVLNQTE DHRQRVLQAA AKTIRVWFIK VRKMKAIYHT LNLCNIDVTQ
     KCLIAEVWCP VSDLDSIQFA LRRGTERSGS TVPSILNRMQ TKQTPPTFNK TNKFTSGFQN
     IVDAYGIGTY REINPAPYTI ITFPFLFAVM FGDMGHGVLM TCAALYLVLR ESRLLAQKSD
     NEMFNMVFAG RYIILLMGIF SVYTGIIYND CFSKSLNMFG SGWSVRPMFG IKGGNWSFET
     LEGNPVLQLD PAIEGVFGGP YPLGIDPIWN IAQNKLTFLN SFKMKMSVIL GVIHMLFGVT
     LSLFNHLYFK KPLNIFLGFI PEIVFMSSLF GYLILLIFYK WTAYNAATSK DAPSLLIAFI
     NMCLFNYSDP TNKPLYRGQM GIQSLLVVIA LACVPCMLIV KTLVLRRQYL WRKHLSQKRE
     ESPAENLESL EQTTVSSSCT GITQQGTQKF GSIRVGNGPT EDEAEIIQHD QLSQHSEDEN
     EVSRW
//
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