ID   A0A0P8CL58_9GAMM        Unreviewed;       415 AA.
AC   A0A0P8CL58;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=Uracil permease {ECO:0000313|EMBL:KPQ23972.1};
GN   Name=pyrP {ECO:0000313|EMBL:KPQ23972.1};
GN   ORFNames=HLUCCA13_11530 {ECO:0000313|EMBL:KPQ23972.1};
OS   Halomonas sp. HL-48.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC   Halomonadaceae; Halomonas.
OX   NCBI_TaxID=1479235 {ECO:0000313|EMBL:KPQ23972.1, ECO:0000313|Proteomes:UP000050569};
RN   [1] {ECO:0000313|EMBL:KPQ23972.1, ECO:0000313|Proteomes:UP000050569}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HL-48 {ECO:0000313|EMBL:KPQ23972.1};
RA   Nelson W.C., Romine M.F., Lindemann S.R.;
RT   "Identification and resolution of microdiversity through metagenomic
RT   sequencing of parallel consortia.";
RL   Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC       2.A.40) family. {ECO:0000256|ARBA:ARBA00008821}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KPQ23972.1}.
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DR   EMBL; LJZS01000013; KPQ23972.1; -; Genomic_DNA.
DR   RefSeq; WP_027335878.1; NZ_LJZS01000013.1.
DR   AlphaFoldDB; A0A0P8CL58; -.
DR   STRING; 1479235.GCA_000686925_00858; -.
DR   PATRIC; fig|1479235.4.peg.159; -.
DR   eggNOG; COG2233; Bacteria.
DR   OrthoDB; 9779092at2; -.
DR   Proteomes; UP000050569; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR   GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:UniProt.
DR   InterPro; IPR006043; NCS2.
DR   InterPro; IPR006042; Xan_ur_permease.
DR   NCBIfam; TIGR00801; ncs2; 1.
DR   PANTHER; PTHR42810; PURINE PERMEASE C1399.01C-RELATED; 1.
DR   PANTHER; PTHR42810:SF4; URIC ACID TRANSPORTER UACT; 1.
DR   Pfam; PF00860; Xan_ur_permease; 1.
DR   PROSITE; PS01116; XANTH_URACIL_PERMASE; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        14..35
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        42..74
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        80..105
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        117..138
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        150..172
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        179..199
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        219..237
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        302..324
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        330..351
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        363..380
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        386..403
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   415 AA;  42994 MW;  E2F63B05669CF71F CRC64;
     MHDASSQPES WPRVLLTGAQ MLFVAFGALV LVPLLTGLDP SVALFTAGVG TLVFHTVTRL
     TVPVFLASSF AFIAPIQGSI ANFGVSATLG GLMVAGLVYV VISIAVRIKG TGWLHRLLPP
     VVVGPVIMVI GLALAPVAVE MATGETSDHI GYGAALFLSM TSLLVTLILA VFGRGLLRLI
     PIMGGIIVGY CLALLMGLVD FTPVQDADWL ALPAFTAPSF HWAAVLFMIP VAIAPAVEHI
     GDMVAIGSVT RRNYLEKPGL HRTLLGDGLA TTVAALFGGP PNTTYSEVTG AVTLTRAFNP
     RYMVVAAVLA ISLAFIAKLG ALLQTIPGPV MGGIMTLLFG SIAVVGMNTL VRAGHSLTAP
     RNLVVVSLIL VFGIGGMQVG GGQFTLQGVS LAALVGIVLN WLLPAEPEDD VADAH
//