ID A0A0P8Y5W2_DROAN Unreviewed; 1966 AA.
AC A0A0P8Y5W2;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 08-NOV-2023, entry version 38.
DE SubName: Full=Uncharacterized protein, isoform H {ECO:0000313|EMBL:KPU74538.1};
GN Name=Dana\GF19013 {ECO:0000313|EMBL:KPU74538.1};
GN Synonyms=dana_GLEANR_20584 {ECO:0000313|EMBL:KPU74538.1};
GN ORFNames=GF19013 {ECO:0000313|EMBL:KPU74538.1};
OS Drosophila ananassae (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7217 {ECO:0000313|EMBL:KPU74538.1, ECO:0000313|Proteomes:UP000007801};
RN [1] {ECO:0000313|EMBL:KPU74538.1, ECO:0000313|Proteomes:UP000007801}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tucson 14024-0371.13 {ECO:0000313|Proteomes:UP000007801};
RX PubMed=17994087; DOI=10.1038/nature06341;
RG Drosophila 12 genomes consortium;
RA Clark A.G., Eisen M.B., Smith D.R., Bergman C.M., Oliver B., Markow T.A.,
RA Kaufman T.C., Kellis M., Gelbart W., Iyer V.N., Pollard D.A., Sackton T.B.,
RA Larracuente A.M., Singh N.D., Abad J.P., Abt D.N., Adryan B., Aguade M.,
RA Akashi H., Anderson W.W., Aquadro C.F., Ardell D.H., Arguello R.,
RA Artieri C.G., Barbash D.A., Barker D., Barsanti P., Batterham P.,
RA Batzoglou S., Begun D., Bhutkar A., Blanco E., Bosak S.A., Bradley R.K.,
RA Brand A.D., Brent M.R., Brooks A.N., Brown R.H., Butlin R.K., Caggese C.,
RA Calvi B.R., Bernardo de Carvalho A., Caspi A., Castrezana S.,
RA Celniker S.E., Chang J.L., Chapple C., Chatterji S., Chinwalla A.,
RA Civetta A., Clifton S.W., Comeron J.M., Costello J.C., Coyne J.A., Daub J.,
RA David R.G., Delcher A.L., Delehaunty K., Do C.B., Ebling H., Edwards K.,
RA Eickbush T., Evans J.D., Filipski A., Findeiss S., Freyhult E., Fulton L.,
RA Fulton R., Garcia A.C., Gardiner A., Garfield D.A., Garvin B.E., Gibson G.,
RA Gilbert D., Gnerre S., Godfrey J., Good R., Gotea V., Gravely B.,
RA Greenberg A.J., Griffiths-Jones S., Gross S., Guigo R., Gustafson E.A.,
RA Haerty W., Hahn M.W., Halligan D.L., Halpern A.L., Halter G.M., Han M.V.,
RA Heger A., Hillier L., Hinrichs A.S., Holmes I., Hoskins R.A., Hubisz M.J.,
RA Hultmark D., Huntley M.A., Jaffe D.B., Jagadeeshan S., Jeck W.R.,
RA Johnson J., Jones C.D., Jordan W.C., Karpen G.H., Kataoka E.,
RA Keightley P.D., Kheradpour P., Kirkness E.F., Koerich L.B., Kristiansen K.,
RA Kudrna D., Kulathinal R.J., Kumar S., Kwok R., Lander E., Langley C.H.,
RA Lapoint R., Lazzaro B.P., Lee S.J., Levesque L., Li R., Lin C.F., Lin M.F.,
RA Lindblad-Toh K., Llopart A., Long M., Low L., Lozovsky E., Lu J., Luo M.,
RA Machado C.A., Makalowski W., Marzo M., Matsuda M., Matzkin L.,
RA McAllister B., McBride C.S., McKernan B., McKernan K., Mendez-Lago M.,
RA Minx P., Mollenhauer M.U., Montooth K., Mount S.M., Mu X., Myers E.,
RA Negre B., Newfeld S., Nielsen R., Noor M.A., O'Grady P., Pachter L.,
RA Papaceit M., Parisi M.J., Parisi M., Parts L., Pedersen J.S., Pesole G.,
RA Phillippy A.M., Ponting C.P., Pop M., Porcelli D., Powell J.R.,
RA Prohaska S., Pruitt K., Puig M., Quesneville H., Ram K.R., Rand D.,
RA Rasmussen M.D., Reed L.K., Reenan R., Reily A., Remington K.A.,
RA Rieger T.T., Ritchie M.G., Robin C., Rogers Y.H., Rohde C., Rozas J.,
RA Rubenfield M.J., Ruiz A., Russo S., Salzberg S.L., Sanchez-Gracia A.,
RA Saranga D.J., Sato H., Schaeffer S.W., Schatz M.C., Schlenke T.,
RA Schwartz R., Segarra C., Singh R.S., Sirot L., Sirota M., Sisneros N.B.,
RA Smith C.D., Smith T.F., Spieth J., Stage D.E., Stark A., Stephan W.,
RA Strausberg R.L., Strempel S., Sturgill D., Sutton G., Sutton G.G., Tao W.,
RA Teichmann S., Tobari Y.N., Tomimura Y., Tsolas J.M., Valente V.L.,
RA Venter E., Venter J.C., Vicario S., Vieira F.G., Vilella A.J.,
RA Villasante A., Walenz B., Wang J., Wasserman M., Watts T., Wilson D.,
RA Wilson R.K., Wing R.A., Wolfner M.F., Wong A., Wong G.K., Wu C.I., Wu G.,
RA Yamamoto D., Yang H.P., Yang S.P., Yorke J.A., Yoshida K., Zdobnov E.,
RA Zhang P., Zhang Y., Zimin A.V., Baldwin J., Abdouelleil A., Abdulkadir J.,
RA Abebe A., Abera B., Abreu J., Acer S.C., Aftuck L., Alexander A., An P.,
RA Anderson E., Anderson S., Arachi H., Azer M., Bachantsang P., Barry A.,
RA Bayul T., Berlin A., Bessette D., Bloom T., Blye J., Boguslavskiy L.,
RA Bonnet C., Boukhgalter B., Bourzgui I., Brown A., Cahill P., Channer S.,
RA Cheshatsang Y., Chuda L., Citroen M., Collymore A., Cooke P., Costello M.,
RA D'Aco K., Daza R., De Haan G., DeGray S., DeMaso C., Dhargay N., Dooley K.,
RA Dooley E., Doricent M., Dorje P., Dorjee K., Dupes A., Elong R., Falk J.,
RA Farina A., Faro S., Ferguson D., Fisher S., Foley C.D., Franke A.,
RA Friedrich D., Gadbois L., Gearin G., Gearin C.R., Giannoukos G., Goode T.,
RA Graham J., Grandbois E., Grewal S., Gyaltsen K., Hafez N., Hagos B.,
RA Hall J., Henson C., Hollinger A., Honan T., Huard M.D., Hughes L.,
RA Hurhula B., Husby M.E., Kamat A., Kanga B., Kashin S., Khazanovich D.,
RA Kisner P., Lance K., Lara M., Lee W., Lennon N., Letendre F., LeVine R.,
RA Lipovsky A., Liu X., Liu J., Liu S., Lokyitsang T., Lokyitsang Y.,
RA Lubonja R., Lui A., MacDonald P., Magnisalis V., Maru K., Matthews C.,
RA McCusker W., McDonough S., Mehta T., Meldrim J., Meneus L., Mihai O.,
RA Mihalev A., Mihova T., Mittelman R., Mlenga V., Montmayeur A., Mulrain L.,
RA Navidi A., Naylor J., Negash T., Nguyen T., Nguyen N., Nicol R., Norbu C.,
RA Norbu N., Novod N., O'Neill B., Osman S., Markiewicz E., Oyono O.L.,
RA Patti C., Phunkhang P., Pierre F., Priest M., Raghuraman S., Rege F.,
RA Reyes R., Rise C., Rogov P., Ross K., Ryan E., Settipalli S., Shea T.,
RA Sherpa N., Shi L., Shih D., Sparrow T., Spaulding J., Stalker J.,
RA Stange-Thomann N., Stavropoulos S., Stone C., Strader C., Tesfaye S.,
RA Thomson T., Thoulutsang Y., Thoulutsang D., Topham K., Topping I.,
RA Tsamla T., Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M.,
RA Wilkinson J., Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D.,
RA Zimmer A., Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J.,
RA Chin C., Gnerre S., Grabherr M., Kleber M., Mauceli E., MacCallum I.;
RT "Evolution of genes and genomes on the Drosophila phylogeny.";
RL Nature 450:203-218(2007).
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DR EMBL; CH902639; KPU74538.1; -; Genomic_DNA.
DR RefSeq; XP_014759504.1; XM_014904018.1.
DR SMR; A0A0P8Y5W2; -.
DR EnsemblMetazoa; FBtr0385406; FBpp0345368; FBgn0096025.
DR Proteomes; UP000007801; Unassembled WGS sequence.
DR GO; GO:0045202; C:synapse; IEA:GOC.
DR GO; GO:0019992; F:diacylglycerol binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0007268; P:chemical synaptic transmission; IEA:InterPro.
DR Gene3D; 3.30.60.20; -; 1.
DR InterPro; IPR046349; C1-like_sf.
DR InterPro; IPR002219; PE/DAG-bd.
DR InterPro; IPR027080; Unc-13.
DR PANTHER; PTHR10480; PROTEIN UNC-13 HOMOLOG; 1.
DR PANTHER; PTHR10480:SF12; UNC-13, ISOFORM E; 1.
DR Pfam; PF00130; C1_1; 1.
DR SMART; SM00109; C1; 1.
DR SUPFAM; SSF57889; Cysteine-rich domain; 1.
DR PROSITE; PS00479; ZF_DAG_PE_1; 1.
DR PROSITE; PS50081; ZF_DAG_PE_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000007801};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 1863..1913
FT /note="Phorbol-ester/DAG-type"
FT /evidence="ECO:0000259|PROSITE:PS50081"
FT REGION 428..454
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1408..1438
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1602..1622
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1752..1798
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1604..1621
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1752..1774
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1966 AA; 222330 MW; 05AC743878C3A411 CRC64;
MYATMLSHPK ALEQTIPNVQ SSPRERIPQQ FDSFQNLKSF STSKSVQMQS HRSLEAPNYN
HSNEIMVSLR SEQELCQIYN SQQHSDYIIS DYMDKIATRV NLLETELKYA WRALDLLSTE
YGKIWVRLEK LENISIEQQS VVSNLMDLIE GANKGPYTDH IEGKKHNSCD DEQLVNSLPL
QIKKKTLERD VIFEMNPSND YSDHEKFTVG RATDRETKLL LNEASAQKPP LDYDSDSYSM
KNFHSENVEY PFTKTYEAEL SQFEENISDQ DKERRKKLYS ESDLLLYQKR QVLANNARVE
LMEEFLNGRR VLNEISGEAG ISTSDFTIPT RPSNNQAINS SHDFNSLNTL NDCNNFFRST
AYKTGEGGNQ VLPIEDTGGT GNEMGELFYR KLNEAYREND LSVEISKVDS ILQKSEVTQE
HIALMNGSIS SSSLETHTPT SDSKKHRKKK HHTNEMDMIN KLKGILSHAK SPIINCNTNE
FLNDRISSQG TDKRDVAGCV SNFSKTRNIA RNKSSFGDDL RITLDNICDT IIDEINKIPG
LQSLNLAQIN EIRQTIWSEE LFFQKLSQVD EKLTLLLLNP ITLSEELRRA NITGSVEKFV
LVMKKFKKNI DTLKKLVCSS LDDYKKSRRH SNVSKAMSTN SINSILIPKE NQGGCSAELL
RTKSDLNEQL KIIETQEIEI CRKQKIDQIV SSHSINPGIL SNHSINQDFK HPQSNMELIS
STNKIYSEDE YIKSLRKSLD RHNSMLFLLH FQNPEKHNII TDLNDMVINP AQISISPPPP
APNNMVNILQ SQRPKNEKSY SDISSISGWA LNSQENCNIE NSSVFNDVTE QSSIQTEAFY
TYPTVSLATL GSLNNLKDLD YKSDIGKPNK KKFVISEENL SYIQELSKNL PICSAYENES
IFDANSKVER LFSVDEMLVW DHLKEHENSN SLINESENAM PDLLTIQSST LLEKKYSPTS
SKKCDEIKGT CISQIGYEEI IKNQSHRYHL NDNLDYYPSP IYLDENNSNN TSNFSGQSNY
IPSIERNTAL SGVAFTSQAL LGDARYNTNL CNDPKLSKLF PESTCELKPI YLYNTLEKQR
SGSKPTKLWN KLFSENLKFK GTAKYNRSQS LPGDMQSQGN QEQARDQAGS CSLISLKRSN
ECENQGQLSK RLQKLPRRIL KRASGAPFVR RFSHQNIAIS SSLNEEPKIC STQIQKKSFS
SKMSHIMQKA KTYKRHDVVL SREGNILGSE LDIPDFTSAE NDFSLCDTKI TINLCESGTS
PTMNQVERGS EKTTKEIYSK NLFSVVGDIK KNRCSLLDAT SHEHVHSTAN QNNTVKISEM
YLQSNVVSET TPCLKKLNSI FIDEDNEEIV LEPNNAGDSF SSFKMPASDF KNFIEISVSI
PTKPTSGRSI NSGGLHLVPQ SLEIPNNLGC GLRDDDDNRS QHSTRTLSSS RRQSTEDSID
TDDEYFYYEL RKLENMEKQR EENSPNSFGN QRVDNEVLFS QIGQLLRNNV NEGCQTSNAV
VEEVERLSYS PDKSVKLQMS LVLNELKCIV KLKPSIDEHN LLKSAVDSVT GGDLEKLMPE
RQNLELVRDM HKAWQDDNGD FKITALELPN NTLTKELKKK KINKSALSNQ AGSTSSSENA
SEYEDKIQDK LFENAVYGDN VSLQSSESSI TSGPDTPAQL SDEMELSCLL MEEDKIKKKG
ADSQKITQKN PQQFGEIRSD TNQINSVVSN SLKDQEFHVE NSHSNVVHGC TAGLGSSKWK
LLKTLKERKI EEKNNQDKKR EEETTKEKEK NGIGAGDVGI RTNGHPGDNP FYSNIDSMPD
IRPRRKSIPL VSELVLKTMA ATKRNAGLTS AVPRATLNDE ELKMHVYKKA LQALIYPISS
TTPHNFLLWT ATSPTYCYEC EGLLWGIARQ GVRCTECGVK CHEKCKDLLN ADCLQRAAEK
SSKHGAEDKA HSIITAMKDR MKQREREKPE IFELISDLCS RPDSEG
//
