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Database: UniProt
Entry: A0A0P8ZIE7_DROAN
LinkDB: A0A0P8ZIE7_DROAN
Original site: A0A0P8ZIE7_DROAN 
ID   A0A0P8ZIE7_DROAN        Unreviewed;      1258 AA.
AC   A0A0P8ZIE7;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   07-JUN-2017, entry version 14.
DE   SubName: Full=Uncharacterized protein, isoform E {ECO:0000313|EMBL:KPU74559.1};
GN   Name=Dana\GF21581 {ECO:0000313|EMBL:KPU74559.1};
GN   ORFNames=Dana_GF21581 {ECO:0000313|EMBL:KPU74559.1}, GF21581
GN   {ECO:0000313|FlyBase:FBgn0098581};
OS   Drosophila ananassae (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha;
OC   Ephydroidea; Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7217 {ECO:0000313|EMBL:KPU74559.1, ECO:0000313|Proteomes:UP000007801};
RN   [1] {ECO:0000313|EMBL:KPU74559.1, ECO:0000313|Proteomes:UP000007801}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tucson 14024-0371.13 {ECO:0000313|Proteomes:UP000007801};
RX   PubMed=17994087; DOI=10.1038/nature06341;
RG   Drosophila 12 Genomes Consortium;
RA   Clark A.G., Eisen M.B., Smith D.R., Bergman C.M., Oliver B.,
RA   Markow T.A., Kaufman T.C., Kellis M., Gelbart W., Iyer V.N.,
RA   Pollard D.A., Sackton T.B., Larracuente A.M., Singh N.D., Abad J.P.,
RA   Abt D.N., Adryan B., Aguade M., Akashi H., Anderson W.W.,
RA   Aquadro C.F., Ardell D.H., Arguello R., Artieri C.G., Barbash D.A.,
RA   Barker D., Barsanti P., Batterham P., Batzoglou S., Begun D.,
RA   Bhutkar A., Blanco E., Bosak S.A., Bradley R.K., Brand A.D.,
RA   Brent M.R., Brooks A.N., Brown R.H., Butlin R.K., Caggese C.,
RA   Calvi B.R., Bernardo de Carvalho A., Caspi A., Castrezana S.,
RA   Celniker S.E., Chang J.L., Chapple C., Chatterji S., Chinwalla A.,
RA   Civetta A., Clifton S.W., Comeron J.M., Costello J.C., Coyne J.A.,
RA   Daub J., David R.G., Delcher A.L., Delehaunty K., Do C.B., Ebling H.,
RA   Edwards K., Eickbush T., Evans J.D., Filipski A., Findeiss S.,
RA   Freyhult E., Fulton L., Fulton R., Garcia A.C., Gardiner A.,
RA   Garfield D.A., Garvin B.E., Gibson G., Gilbert D., Gnerre S.,
RA   Godfrey J., Good R., Gotea V., Gravely B., Greenberg A.J.,
RA   Griffiths-Jones S., Gross S., Guigo R., Gustafson E.A., Haerty W.,
RA   Hahn M.W., Halligan D.L., Halpern A.L., Halter G.M., Han M.V.,
RA   Heger A., Hillier L., Hinrichs A.S., Holmes I., Hoskins R.A.,
RA   Hubisz M.J., Hultmark D., Huntley M.A., Jaffe D.B., Jagadeeshan S.,
RA   Jeck W.R., Johnson J., Jones C.D., Jordan W.C., Karpen G.H.,
RA   Kataoka E., Keightley P.D., Kheradpour P., Kirkness E.F.,
RA   Koerich L.B., Kristiansen K., Kudrna D., Kulathinal R.J., Kumar S.,
RA   Kwok R., Lander E., Langley C.H., Lapoint R., Lazzaro B.P., Lee S.J.,
RA   Levesque L., Li R., Lin C.F., Lin M.F., Lindblad-Toh K., Llopart A.,
RA   Long M., Low L., Lozovsky E., Lu J., Luo M., Machado C.A.,
RA   Makalowski W., Marzo M., Matsuda M., Matzkin L., McAllister B.,
RA   McBride C.S., McKernan B., McKernan K., Mendez-Lago M., Minx P.,
RA   Mollenhauer M.U., Montooth K., Mount S.M., Mu X., Myers E., Negre B.,
RA   Newfeld S., Nielsen R., Noor M.A., O'Grady P., Pachter L.,
RA   Papaceit M., Parisi M.J., Parisi M., Parts L., Pedersen J.S.,
RA   Pesole G., Phillippy A.M., Ponting C.P., Pop M., Porcelli D.,
RA   Powell J.R., Prohaska S., Pruitt K., Puig M., Quesneville H.,
RA   Ram K.R., Rand D., Rasmussen M.D., Reed L.K., Reenan R., Reily A.,
RA   Remington K.A., Rieger T.T., Ritchie M.G., Robin C., Rogers Y.H.,
RA   Rohde C., Rozas J., Rubenfield M.J., Ruiz A., Russo S., Salzberg S.L.,
RA   Sanchez-Gracia A., Saranga D.J., Sato H., Schaeffer S.W., Schatz M.C.,
RA   Schlenke T., Schwartz R., Segarra C., Singh R.S., Sirot L., Sirota M.,
RA   Sisneros N.B., Smith C.D., Smith T.F., Spieth J., Stage D.E.,
RA   Stark A., Stephan W., Strausberg R.L., Strempel S., Sturgill D.,
RA   Sutton G., Sutton G.G., Tao W., Teichmann S., Tobari Y.N.,
RA   Tomimura Y., Tsolas J.M., Valente V.L., Venter E., Venter J.C.,
RA   Vicario S., Vieira F.G., Vilella A.J., Villasante A., Walenz B.,
RA   Wang J., Wasserman M., Watts T., Wilson D., Wilson R.K., Wing R.A.,
RA   Wolfner M.F., Wong A., Wong G.K., Wu C.I., Wu G., Yamamoto D.,
RA   Yang H.P., Yang S.P., Yorke J.A., Yoshida K., Zdobnov E., Zhang P.,
RA   Zhang Y., Zimin A.V., Baldwin J., Abdouelleil A., Abdulkadir J.,
RA   Abebe A., Abera B., Abreu J., Acer S.C., Aftuck L., Alexander A.,
RA   An P., Anderson E., Anderson S., Arachi H., Azer M., Bachantsang P.,
RA   Barry A., Bayul T., Berlin A., Bessette D., Bloom T., Blye J.,
RA   Boguslavskiy L., Bonnet C., Boukhgalter B., Bourzgui I., Brown A.,
RA   Cahill P., Channer S., Cheshatsang Y., Chuda L., Citroen M.,
RA   Collymore A., Cooke P., Costello M., D'Aco K., Daza R., De Haan G.,
RA   DeGray S., DeMaso C., Dhargay N., Dooley K., Dooley E., Doricent M.,
RA   Dorje P., Dorjee K., Dupes A., Elong R., Falk J., Farina A., Faro S.,
RA   Ferguson D., Fisher S., Foley C.D., Franke A., Friedrich D.,
RA   Gadbois L., Gearin G., Gearin C.R., Giannoukos G., Goode T.,
RA   Graham J., Grandbois E., Grewal S., Gyaltsen K., Hafez N., Hagos B.,
RA   Hall J., Henson C., Hollinger A., Honan T., Huard M.D., Hughes L.,
RA   Hurhula B., Husby M.E., Kamat A., Kanga B., Kashin S., Khazanovich D.,
RA   Kisner P., Lance K., Lara M., Lee W., Lennon N., Letendre F.,
RA   LeVine R., Lipovsky A., Liu X., Liu J., Liu S., Lokyitsang T.,
RA   Lokyitsang Y., Lubonja R., Lui A., MacDonald P., Magnisalis V.,
RA   Maru K., Matthews C., McCusker W., McDonough S., Mehta T., Meldrim J.,
RA   Meneus L., Mihai O., Mihalev A., Mihova T., Mittelman R., Mlenga V.,
RA   Montmayeur A., Mulrain L., Navidi A., Naylor J., Negash T., Nguyen T.,
RA   Nguyen N., Nicol R., Norbu C., Norbu N., Novod N., O'Neill B.,
RA   Osman S., Markiewicz E., Oyono O.L., Patti C., Phunkhang P.,
RA   Pierre F., Priest M., Raghuraman S., Rege F., Reyes R., Rise C.,
RA   Rogov P., Ross K., Ryan E., Settipalli S., Shea T., Sherpa N., Shi L.,
RA   Shih D., Sparrow T., Spaulding J., Stalker J., Stange-Thomann N.,
RA   Stavropoulos S., Stone C., Strader C., Tesfaye S., Thomson T.,
RA   Thoulutsang Y., Thoulutsang D., Topham K., Topping I., Tsamla T.,
RA   Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M., Wilkinson J.,
RA   Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D., Zimmer A.,
RA   Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J., Chin C.,
RA   Gnerre S., Grabherr M., Kleber M., Mauceli E., MacCallum I.;
RT   "Evolution of genes and genomes on the Drosophila phylogeny.";
RL   Nature 450:203-218(2007).
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00448}.
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DR   EMBL; CH902654; KPU74559.1; -; Genomic_DNA.
DR   RefSeq; XP_014759227.1; XM_014903741.1.
DR   GeneID; 6504257; -.
DR   FlyBase; FBgn0098581; Dana\GF21581.
DR   Proteomes; UP000007801; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005216; F:ion channel activity; IEA:InterPro.
DR   InterPro; IPR002048; EF_hand_dom.
DR   InterPro; IPR031649; GPHH_dom.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR003915; PKD_2.
DR   InterPro; IPR014873; VDCC_a1su_IQ.
DR   Pfam; PF08763; Ca_chan_IQ; 1.
DR   Pfam; PF16905; GPHH; 1.
DR   Pfam; PF00520; Ion_trans; 2.
DR   PRINTS; PR01433; POLYCYSTIN2.
DR   SMART; SM01062; Ca_chan_IQ; 1.
DR   PROSITE; PS50222; EF_HAND_2; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000007801};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007801};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     70     89       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    109    130       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    139    157       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    206    228       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    320    345       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    401    419       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    431    449       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    525    543       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    614    639       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      655    690       EF-hand. {ECO:0000259|PROSITE:PS50222}.
SQ   SEQUENCE   1258 AA;  144654 MW;  71493F6F156FB6D5 CRC64;
     MEALQGDGVH VENGDGTIAT TKGKNKRKEE EKKEEEEVTE GPKPMLPYSS MFILSPTNPI
     RRGAHWVVNL PYFDFFIMVV ISMSSIALAA EDPVRENSRR NKILNYFDYA FTGVFTIEML
     LKIVDLGVIL HPGSYLREFW NIMDAVVVIC AAVSFGFDMS GSSAGQNLST IKSLRVLRVL
     RPLKTIKRVP KLKAVFDCVV NSLKNVVNIL IVYILFQFIF SVIGVQLFNG KFFYCTDESK
     HTSAECQGSY FKYEEDELLP KQELRVWKPR AFHYDNVAAA MLTLFAVQTG EGWPQVLQHS
     MAATYEDRGP IQNFRIEMSI FYIVYFIVFP FFFVNIFVAL IIITFQEQGE AELQDGEIDK
     NQKSCIDFTI GARPLERYMP KNRNTFKYKV WRIVVSTPFE YFIMMLIVFN TLLLMMKYHN
     QGDMYEKSLK YINMGFTGMF SVETVLKIIG FGVKNFFKDP WNIFDLITVL GSIVDALWME
     FGHDDSNSIN VGFLRLFRAA RLIKLLRQGY TIRILLWTFV QSFKALPYVC LLIAMLFFIY
     AIIGMQVFGN IKLGTVENSI TRHNNFQSFI QGVMLLFRCA TGEAWPNIML ACLKGKACDE
     DAEKRPGEYC GSTLAYAYFV SFIFFCSFLM LNLFVAVIMD NFDYLTRDSS ILGAHHLDEF
     VRIWAEYDPN ATGKIHYTEM YDMLKNMDPP LGFGNKCPNR LAYKKLIRMN MPLDDELRVQ
     FTTTLFALIR ENLSIKMRAP EEMDQADLEL RETITNIWPL QAKKMLNLLV PPSDQLNKGK
     LSVGKIYAGF LILESWRSTR FGQIDSGMPR KKQEDDDERV YSPTTIEEPK QSFFNCLLDM
     AALDKGGSRQ GSISFEPNGE GAANSQTHLL ASTHHHHPNG DAEHNSLATL ARRSTIRKRS
     VRNKKVNKFD KLQAMLELQD ASRHPSQESL TGADASHLHP GLSYMNGHRQ SPSLRHNGSP
     LARSPSPRRR GHQYIHHDIG FSDTVSNVVE MVKETRHPRH GNSHPRYPRG SWSASTSPAR
     SPSPSRYGGH LSRSKRTQLP YPTYGTTSLC QRSRSPSPAR LQEMRERDRL GYGINMGGTH
     VQHSYPTLAS RRAGIGRRLP PTPSKPSTLQ LKPTNINFPK LNASPTHTHH STPHSVHSLP
     HHRDLLRDPR DVYYSSRDRE RDRERLRDRD RDRDRDRLHE YDLRYEYRDR ERELYERERD
     REREVERERL EYIAPLSFEQ ALAMGRTGRV LPSPVLNGFK PKTGLNTRHS DSDEEDWC
//
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