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Database: UniProt
Entry: A0A0P9DUM5_9ARCH
LinkDB: A0A0P9DUM5_9ARCH
Original site: A0A0P9DUM5_9ARCH 
ID   A0A0P9DUM5_9ARCH        Unreviewed;       313 AA.
AC   A0A0P9DUM5;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   25-OCT-2017, entry version 14.
DE   RecName: Full=Transcription initiation factor IIB {ECO:0000256|HAMAP-Rule:MF_00383};
DE            Short=TFIIB {ECO:0000256|HAMAP-Rule:MF_00383};
GN   Name=tfb {ECO:0000256|HAMAP-Rule:MF_00383,
GN   ECO:0000313|EMBL:KPV62489.1};
GN   ORFNames=AOA65_1804 {ECO:0000313|EMBL:KPV62489.1};
OS   Candidatus Bathyarchaeota archaeon BA1.
OC   Archaea; Candidatus Bathyarchaeota.
OX   NCBI_TaxID=1700835 {ECO:0000313|EMBL:KPV62489.1, ECO:0000313|Proteomes:UP000050312};
RN   [1] {ECO:0000313|EMBL:KPV62489.1, ECO:0000313|Proteomes:UP000050312}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BA1 {ECO:0000313|EMBL:KPV62489.1};
RX   PubMed=26494757; DOI=10.1126/science.aac7745;
RA   Evans P.N., Parks D.H., Chadwick G.L., Robbins S.J., Orphan V.J.,
RA   Golding S.D., Tyson G.W.;
RT   "Methane metabolism in the archaeal phylum Bathyarchaeota revealed by
RT   genome-centric metagenomics.";
RL   Science 350:434-438(2015).
CC   -!- FUNCTION: Stabilizes TBP binding to an archaeal box-A promoter.
CC       Also responsible for recruiting RNA polymerase II to the pre-
CC       initiation complex (DNA-TBP-TFIIB). {ECO:0000256|HAMAP-
CC       Rule:MF_00383}.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence={ECO:0000256|HAMAP-
CC         Rule:MF_00383};
CC       Note=Binds 1 zinc ion per subunit. {ECO:0000256|HAMAP-
CC       Rule:MF_00383};
CC   -!- SIMILARITY: Belongs to the TFIIB family. {ECO:0000256|HAMAP-
CC       Rule:MF_00383}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KPV62489.1}.
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DR   EMBL; LIHJ01000077; KPV62489.1; -; Genomic_DNA.
DR   EnsemblBacteria; KPV62489; KPV62489; AOA65_1804.
DR   KEGG; barc:AOA65_1804; -.
DR   PATRIC; fig|1700835.3.peg.2561; -.
DR   KO; K03124; -.
DR   Proteomes; UP000050312; Unassembled WGS sequence.
DR   GO; GO:0017025; F:TBP-class protein binding; IEA:InterPro.
DR   GO; GO:0003700; F:transcription factor activity, sequence-specific DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0070897; P:DNA-templated transcriptional preinitiation complex assembly; IEA:InterPro.
DR   CDD; cd00043; CYCLIN; 1.
DR   Gene3D; 1.10.472.10; -; 2.
DR   HAMAP; MF_00383; TF2B_arch; 1.
DR   InterPro; IPR013763; Cyclin-like.
DR   InterPro; IPR036915; Cyclin-like_sf.
DR   InterPro; IPR000812; TFIIB.
DR   InterPro; IPR023484; TFIIB_arc.
DR   InterPro; IPR013150; TFIIB_cyclin.
DR   InterPro; IPR013137; Znf_TFIIB.
DR   PANTHER; PTHR11618; PTHR11618; 1.
DR   Pfam; PF08271; TF_Zn_Ribbon; 1.
DR   Pfam; PF00382; TFIIB; 2.
DR   PRINTS; PR00685; TIFACTORIIB.
DR   SMART; SM00385; CYCLIN; 2.
DR   SUPFAM; SSF47954; SSF47954; 2.
DR   PROSITE; PS51134; ZF_TFIIB; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000050312};
KW   Initiation factor {ECO:0000313|EMBL:KPV62489.1};
KW   Metal-binding {ECO:0000256|HAMAP-Rule:MF_00383, ECO:0000256|PROSITE-
KW   ProRule:PRU00469};
KW   Protein biosynthesis {ECO:0000313|EMBL:KPV62489.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000050312};
KW   Repeat {ECO:0000256|HAMAP-Rule:MF_00383};
KW   Transcription {ECO:0000256|HAMAP-Rule:MF_00383};
KW   Transcription regulation {ECO:0000256|HAMAP-Rule:MF_00383};
KW   Zinc {ECO:0000256|HAMAP-Rule:MF_00383, ECO:0000256|PROSITE-
KW   ProRule:PRU00469};
KW   Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00469}.
FT   DOMAIN       13     44       TFIIB-type. {ECO:0000259|PROSITE:
FT                                PS51134}.
FT   REPEAT      130    213       1. {ECO:0000256|HAMAP-Rule:MF_00383}.
FT   REPEAT      224    305       2. {ECO:0000256|HAMAP-Rule:MF_00383}.
FT   ZN_FING      13     44       TFIIB-type. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00469}.
FT   METAL        17     17       Zinc. {ECO:0000256|HAMAP-Rule:MF_00383}.
FT   METAL        20     20       Zinc. {ECO:0000256|HAMAP-Rule:MF_00383}.
FT   METAL        36     36       Zinc. {ECO:0000256|HAMAP-Rule:MF_00383}.
FT   METAL        39     39       Zinc. {ECO:0000256|HAMAP-Rule:MF_00383}.
SQ   SEQUENCE   313 AA;  35469 MW;  063C896242D040BB CRC64;
     MSDEEDVLTS PLKVQRCPEC GSTRLMRDYE LAEIVCMSCG FVVAAKLTDR GPEWRAFDDE
     QRAKRTRVGA PLTFTIHDKG LSTMIDWHDR DIYGKRLTPG QRAQIYRLRK WQRRIRVSDA
     TERNLAFALS EISKIANNLN LPKNILETAS VIYRKAVKEH LIRGRSIQGV TAAAIYVACR
     QCGLARTLEE IAIASSINKK EVGRSYRFLI KELDYFIPPL TPSQYITKFS NQLTMQGKVE
     EIAHKILTTA RDLKLTSGRG PTGIAAAASY IASMLIGERK TQREIAEIAQ VTEVTIRNRY
     KELADRLMFV VTL
//
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