ID A0A0Q3MJH0_AMAAE Unreviewed; 2211 AA.
AC A0A0Q3MJH0;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE RecName: Full=Activating signal cointegrator 1 complex subunit 3 {ECO:0000256|ARBA:ARBA00014590};
GN ORFNames=AAES_71590 {ECO:0000313|EMBL:KQK82663.1};
OS Amazona aestiva (Blue-fronted Amazon parrot).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Psittaciformes; Psittacidae; Amazona.
OX NCBI_TaxID=12930 {ECO:0000313|EMBL:KQK82663.1, ECO:0000313|Proteomes:UP000051836};
RN [1] {ECO:0000313|EMBL:KQK82663.1, ECO:0000313|Proteomes:UP000051836}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FVVF132 {ECO:0000313|EMBL:KQK82663.1};
RA Gilbert D.G.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the helicase family.
CC {ECO:0000256|ARBA:ARBA00008708}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KQK82663.1}.
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DR EMBL; LMAW01001780; KQK82663.1; -; Genomic_DNA.
DR STRING; 12930.A0A0Q3MJH0; -.
DR Proteomes; UP000051836; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0010467; P:gene expression; IEA:UniProt.
DR GO; GO:0090304; P:nucleic acid metabolic process; IEA:UniProt.
DR CDD; cd18020; DEXHc_ASCC3_1; 1.
DR CDD; cd18022; DEXHc_ASCC3_2; 1.
DR CDD; cd18795; SF2_C_Ski2; 2.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 2.60.40.150; C2 domain; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 4.
DR Gene3D; 1.10.3380.10; Sec63 N-terminal domain-like domain; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR004179; Sec63-dom.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR47961; DNA POLYMERASE THETA, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05260)-RELATED; 1.
DR PANTHER; PTHR47961:SF13; SEC63 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00270; DEAD; 2.
DR Pfam; PF00271; Helicase_C; 2.
DR Pfam; PF02889; Sec63; 2.
DR PIRSF; PIRSF039073; BRR2; 1.
DR SMART; SM00382; AAA; 2.
DR SMART; SM00487; DEXDc; 2.
DR SMART; SM00490; HELICc; 2.
DR SMART; SM00973; Sec63; 2.
DR SUPFAM; SSF81296; E set domains; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 3.
DR SUPFAM; SSF158702; Sec63 N-terminal domain-like; 2.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 2.
DR PROSITE; PS51194; HELICASE_CTER; 2.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000051836}.
FT DOMAIN 495..678
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 717..923
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT DOMAIN 1345..1520
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 1553..1760
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
SQ SEQUENCE 2211 AA; 251825 MW; 9B9D8B80EEE44B2F CRC64;
MALPRLTGAL RSFSNVTKHE DYSEELADLT TKRSKLHGQL LKSDLTWKKI IKFVDDNLDK
REHQTVNGDL KTILQAAKQI VGAENGQEAI ESGAVFLFKT FHRKECVGHN ETKAIKQMFG
PFPSSSATAA CNATCRIASH FTEEQLTALI QMAEEQSDEN RVVFGKNIVF SFDMHDLDHS
EELPVNGEAD AQNTISLDYN KFLNNQLNHL QNYCGEKSDL KSLEKVDDSF LWSEVGKYLN
ESQGGTPGGP TTEDLCCTLY EMLASTKSGD ELQNELFELL GPEGFELIEK LLQNRSVILE
RSLACPNDNR FQALQEQCKK FIGENAKPSY GCQVTIQSEQ ERLLMKQYRR EEKRNARKEK
QTGEDAEVSG EGLMCFDPKE LRMQRELSLL NARSMPVLGR QREMEFEKIH YPHVYDSRAE
AMKTSAFIGG AKVFLPEAVQ RENNKMYEEV KIPHSEPMPI GIEEKIVYIK DLDEIGQLAF
KGMKRLNRIQ SIVFETAYNT NENMLICAPT GAGKTNIAML TILHEIRQHV QQGVIKKDEF
KIVYVAPMKA LAAEMTNYFS KRLEPLGITV KELTGDMQLS KGEILRTQML VTTPEKWDVV
TRKSVGDVAL SQMVKLLILD EVHLLHEDRG PVLESIVART LRQVESTQSM IRILGLSATL
PNYLDVATFL HVNPYIGLFY FDGRFRPVPL GQTFVGIKTA NKVQQLNHMD EVCYENVLKQ
IMAGHQVMVF VHARNATVRT AMGLREKAKN NGHICHFLSP QGSDYGQAEK QVQRSRNKQL
RELFPDGFSI HHAGMLRQDR NLVENLFSNG HIKVLVCTAT LAWGVNLPAH AVVIKGTQIY
AAKRGSFVDL GILDVMQIFG RAGRPQFDKF GEGIIITTHD KLSHYLTLLT QQNPIESQFL
ESLADNLNAE IALGTVTNVE EAVKWISYTY LXVRMRANPL VYGISHKAYQ MDPGLEKHRE
QLVIEVGRKL DKARMIRFEE RTGFFSSTDL GRTASHYYIK YNTIETFNEL FDAHKTEGDI
LAIVSKAEEF EQIKVREEEI EELDTLLNDF CELPAPGGVE NNYGKINILL QTYISRGEMX
SFSLISDSAY VAQNAARIVR ALFEIALRKR WPAMTYRLLN LSKVIDKRLW GWVSPLRQFS
VLPPSVLSKL EEKNLTIDKM KDMRKDEIGH MLHHVKIGLK VKQCVHQIPS VIMEATIQPI
TRTVLRVRLN ITPDFTWNDQ VHGTVGEPWW IWVEDPTNDH IYHSEYFIVQ KKQVITKEPQ
LLVFTIPIFE PLPSQYYIRA VSDRWLGAEA VCIINFQHLI LPERHPPHTE LLDLQPLPIT
ALGHREYEAL YKFTHFNPIQ TQIFHTLYHT DCNVLLGAPT GSGKTVAAEL AIFRVFNKYP
TSKAVYIAPL KALVRERIED WKVRIEEKLG KKVVELTGDV TPDMRAIAQA DLIVTTPEKW
DGVSRSWQNR SYVQKVSILI IDEIHLLGDE RGPVLEVIVS RTNFISSHTE KPVRVVGLST
ALANARDLAD WLNINQMGLF NFRPSVRPVP LEVHIQGFPG QHYCPRMASM NKPAFQAIRS
HSPAKPVLIF VSSRRQTRLT ALDLIAFLAT EDDPKQWLKM DEREMNDIIA TVRDSNLKLT
LAFGIGMHHA GLHERDRKTV EELFVNCKIQ VLIATSTLAW GVNFPAHLVI VKGTEYYDGK
TRRYVDYPIT DVLQMMGRAG RPQFDDQGKA VILVHDIKKD FYKKFLYEPF PVESSLLEVL
ADHLNAEIAA GTITSKQDAM DYITWTYFFR RLIMNPTYYN LDDVSHDTMN KYLSSLVEKS
LFDLECSYCI EIGEDNCSIE PLTYGRIASY YYLKHPTIGM FKDQLKPESN IEELLLILTN
AEEYTDLPVR HNEDQMNSEL AKHLPIEVNP HSFDSSHTKT HLLLQAHFSH AMLPCPDYAT
DTKTVLDQAI RICQAMLDVX AHHGWLVTAL NIINLVQMVV QGRWIHNSSL LTLPNIELQH
LYLFRKWSQG KRKSLHGGYQ GPIECLPELM AACEGKEHVF ASIVDGELQT AHISQAWNFL
CRLPILNINL SIKGCWDDPA QPQXEVPVPS LTTDTRDDNR WIKLHADQEY VLQINLQRTQ
MGYQGRQDSK AVAPRFPKVK DEGWFLILGE VDKKELIALK RTGYVRNRST VSVAFYTPET
PGKCIYTLYL MSDSYLGMDQ QYDIYLNIIP ASTSAQVTTD VSDTLSHLTL K
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