ID A0A0Q3R775_SETIT Unreviewed; 629 AA.
AC A0A0Q3R775;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=NB-ARC domain-containing protein {ECO:0008006|Google:ProtNLM};
OS Setaria italica (Foxtail millet) (Panicum italicum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Panicodae; Paniceae; Cenchrinae; Setaria.
OX NCBI_TaxID=4555 {ECO:0000313|EnsemblPlants:KQL25926, ECO:0000313|Proteomes:UP000004995};
RN [1] {ECO:0000313|EnsemblPlants:KQL25926, ECO:0000313|Proteomes:UP000004995}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Yugu1 {ECO:0000313|EnsemblPlants:KQL25926,
RC ECO:0000313|Proteomes:UP000004995};
RX PubMed=22580951; DOI=10.1038/nbt.2196;
RA Bennetzen J.L., Schmutz J., Wang H., Percifield R., Hawkins J.,
RA Pontaroli A.C., Estep M., Feng L., Vaughn J.N., Grimwood J., Jenkins J.,
RA Barry K., Lindquist E., Hellsten U., Deshpande S., Wang X., Wu X.,
RA Mitros T., Triplett J., Yang X., Ye C.Y., Mauro-Herrera M., Wang L., Li P.,
RA Sharma M., Sharma R., Ronald P.C., Panaud O., Kellogg E.A., Brutnell T.P.,
RA Doust A.N., Tuskan G.A., Rokhsar D., Devos K.M.;
RT "Reference genome sequence of the model plant Setaria.";
RL Nat. Biotechnol. 30:555-561(2012).
RN [2] {ECO:0000313|EnsemblPlants:KQL25926}
RP IDENTIFICATION.
RC STRAIN=Yugu1 {ECO:0000313|EnsemblPlants:KQL25926};
RG EnsemblPlants;
RL Submitted (AUG-2018) to UniProtKB.
CC -!- SIMILARITY: Belongs to the disease resistance NB-LRR family.
CC {ECO:0000256|ARBA:ARBA00008894}.
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DR EMBL; AGNK02001262; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A0Q3R775; -.
DR STRING; 4555.A0A0Q3R775; -.
DR EnsemblPlants; KQL25926; KQL25926; SETIT_0333791mg.
DR Gramene; KQL25926; KQL25926; SETIT_0333791mg.
DR eggNOG; KOG4658; Eukaryota.
DR InParanoid; A0A0Q3R775; -.
DR Proteomes; UP000004995; Chromosome II.
DR ExpressionAtlas; A0A0Q3R775; baseline.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR GO; GO:0051707; P:response to other organism; IEA:UniProt.
DR CDD; cd14798; RX-CC_like; 1.
DR Gene3D; 1.20.5.4130; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038005; RX-like_CC.
DR InterPro; IPR041118; Rx_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR23155; DISEASE RESISTANCE PROTEIN RP; 1.
DR PANTHER; PTHR23155:SF906; NB-ARC DOMAIN CONTAINING PROTEIN, EXPRESSED; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF18052; Rx_N; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Plant defense {ECO:0000256|ARBA:ARBA00022821};
KW Reference proteome {ECO:0000313|Proteomes:UP000004995}.
FT DOMAIN 1..65
FT /note="Disease resistance N-terminal"
FT /evidence="ECO:0000259|Pfam:PF18052"
FT DOMAIN 140..253
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
FT COILED 85..112
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 629 AA; 70510 MW; D39AF8AFC183B2FE CRC64;
MESVLAKLAQ LMGDKCSNLI DLSSDTAFLR DELCTINALL KKLDHEDEDA LDPQVKDWSN
QVRDVDARAG FFRRIAHFIG TLRACLETAK HIKELKTRLQ EINERRKRYR LEHCIASSSS
AGIDPRLPAL CKEAANLKQL KGVTIVGFGG LGKTTLANEV YHRVKGQFDF HAFVSVSQRP
DMARLLNSIR LKLGQQESSY PREVKDLIDN PFLKCSSSES IEELSMLSLY NCNYPNQHRI
FDDLWDTISW NTIKCGGLPL AIITVASILA SKPTSKKEDW EKIRNSLGSD LGTHPTLAGM
RQILRLSYRN LPHHLRTCFL YLGIYPEDHI IRKVDLVRQW VAEGLVSNSG RQDAEDLANS
YFDELVNRSM TQPEEIDYNG KVLSCRVHDM MLDLILSKCT EDNFINVLYD SQGMRELQNS
KVRRLSLNLN GAEGFTISAV QAVGSQSQIR SLALFGATTC MPACAHLFPE SKFLRVLVLE
LRQLVLLRYL KVEARSSCVK LPTEIQGLRH LETLEMSCGF VGGIPSDVFH LPGLLHLDIA
STPGGFPGGI NTAHGRSSMN ALRSSLGKLG GSNLRCLSVV RYPEIRDDML SSLAPPPHRL
ETLDLLAWCL SRVPRWLAEL HNLCSLDLC
//
