ID   A0A0Q3RFJ6_AMAAE        Unreviewed;       402 AA.
AC   A0A0Q3RFJ6;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   RecName: Full=Lipase {ECO:0000256|PIRNR:PIRNR000862};
GN   ORFNames=AAES_53161 {ECO:0000313|EMBL:KQK84353.1};
OS   Amazona aestiva (Blue-fronted Amazon parrot).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Psittaciformes; Psittacidae; Amazona.
OX   NCBI_TaxID=12930 {ECO:0000313|EMBL:KQK84353.1, ECO:0000313|Proteomes:UP000051836};
RN   [1] {ECO:0000313|EMBL:KQK84353.1, ECO:0000313|Proteomes:UP000051836}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FVVF132 {ECO:0000313|EMBL:KQK84353.1};
RA   Gilbert D.G.;
RL   Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the AB hydrolase superfamily. Lipase family.
CC       {ECO:0000256|ARBA:ARBA00010701, ECO:0000256|PIRNR:PIRNR000862}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KQK84353.1}.
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DR   EMBL; LMAW01001114; KQK84353.1; -; Genomic_DNA.
DR   STRING; 12930.A0A0Q3RFJ6; -.
DR   Proteomes; UP000051836; Unassembled WGS sequence.
DR   GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR006693; AB_hydrolase_lipase.
DR   InterPro; IPR025483; Lipase_euk.
DR   PANTHER; PTHR11005; LYSOSOMAL ACID LIPASE-RELATED; 1.
DR   PANTHER; PTHR11005:SF26; LYSOSOMAL ACID LIPASE_CHOLESTERYL ESTER HYDROLASE; 1.
DR   Pfam; PF04083; Abhydro_lipase; 1.
DR   PIRSF; PIRSF000862; Steryl_ester_lip; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PIRNR:PIRNR000862};
KW   Lipid degradation {ECO:0000256|PIRNR:PIRNR000862};
KW   Lipid metabolism {ECO:0000256|PIRNR:PIRNR000862};
KW   Reference proteome {ECO:0000313|Proteomes:UP000051836};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           19..402
FT                   /note="Lipase"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5006207106"
FT   DOMAIN          44..105
FT                   /note="Partial AB-hydrolase lipase"
FT                   /evidence="ECO:0000259|Pfam:PF04083"
FT   ACT_SITE        180
FT                   /note="Nucleophile"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000862-1"
FT   ACT_SITE        348
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000862-1"
FT   ACT_SITE        377
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000862-1"
SQ   SEQUENCE   402 AA;  45472 MW;  11F55B30641927BE CRC64;
     MWCLFMLFCS QAITFSAGFK TPSTLYSDKS QFRKPRNPES FMNVSEIIRY HGYPSEEYEV
     TTEDGYILSV FRIPAGRNSQ TTGKKPAILL HHGTLGDSIH WISNLSNSSL GFILADAGYD
     VWLGNSRGNT WSLKHKTLKP CQKEFWQFSF DEIGKYDVRG ELYFIMNKTG QKDVYFVGHS
     EAATAGFVAF ATYPELAQRV KVFFALGPVV TTTYGTSPLV TAVRLPQFLI RLFAGCKGIF
     RQNELLKPLL VRLCESLGKF CGSVLGYVAG DKVQNLNTSR TDVYVGHYPA GTSVQNGLHW
     HQVIYADQLQ AYDYGSKENM KKYNQSTPPV YKIEEISTPI AVWSGALDKF ADPKDTAKLL
     PXIKNLIYYE HFPSWGHLSF IWGLDAPQKL YQKIVELLEK HP
//