ID   A0A0Q3TGE2_AMAAE        Unreviewed;       955 AA.
AC   A0A0Q3TGE2;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   24-JAN-2024, entry version 23.
DE   SubName: Full=Run domain Beclin-1 interacting and cysteine-rich containing protein {ECO:0000313|EMBL:KQK79630.1};
GN   ORFNames=AAES_223890 {ECO:0000313|EMBL:KQK79630.1};
OS   Amazona aestiva (Blue-fronted Amazon parrot).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Psittaciformes; Psittacidae; Amazona.
OX   NCBI_TaxID=12930 {ECO:0000313|EMBL:KQK79630.1, ECO:0000313|Proteomes:UP000051836};
RN   [1] {ECO:0000313|EMBL:KQK79630.1, ECO:0000313|Proteomes:UP000051836}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FVVF132 {ECO:0000313|EMBL:KQK79630.1};
RA   Gilbert D.G.;
RL   Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KQK79630.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; LMAW01002575; KQK79630.1; -; Genomic_DNA.
DR   STRING; 12930.A0A0Q3TGE2; -.
DR   Proteomes; UP000051836; Unassembled WGS sequence.
DR   GO; GO:0005768; C:endosome; IEA:UniProtKB-KW.
DR   GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
DR   CDD; cd17686; RUN_RUBCN; 1.
DR   Gene3D; 1.20.58.900; -; 1.
DR   InterPro; IPR025258; RH_dom.
DR   InterPro; IPR048569; RUBC_PIKBD.
DR   InterPro; IPR004012; Run_dom.
DR   InterPro; IPR037213; Run_dom_sf.
DR   PANTHER; PTHR45971; PHOX (PX) DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR45971:SF3; RUN DOMAIN BECLIN-1-INTERACTING AND CYSTEINE-RICH DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF13901; RH_dom; 1.
DR   Pfam; PF21054; RUBC_PIKBD; 1.
DR   Pfam; PF02759; RUN; 1.
DR   SMART; SM01175; DUF4206; 1.
DR   SMART; SM00593; RUN; 1.
DR   SUPFAM; SSF140741; RUN domain-like; 1.
DR   PROSITE; PS50826; RUN; 1.
PE   4: Predicted;
KW   Autophagy {ECO:0000256|ARBA:ARBA00023006};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Endosome {ECO:0000256|ARBA:ARBA00022753};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000051836}.
FT   DOMAIN          34..175
FT                   /note="RUN"
FT                   /evidence="ECO:0000259|PROSITE:PS50826"
FT   REGION          224..437
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          502..529
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        224..309
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        326..364
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        372..394
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        395..419
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        420..437
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   955 AA;  106441 MW;  E369A1C1836741E1 CRC64;
     MVPQFNSRKE HWKLLGNLKT TVEGLVSTSN PNVWSKYGGL ERLCRDMHSI LYHGLIHDKV
     CCRQKDYWQF VKDIRWLSPG SAHHLEKFIS LQESGQPDPE GPGDQAIAQL WLQHSLQCHC
     LSAQLRPLLG NRQYIRKFYS DTAFLLSDAH VTAMLQCLEA VEQNNPRLLA QIDTSMLTRK
     SDGPPPVTKS QSLTALPASP CIPVAGCMQQ RCFGSVSSLH SPAFSGLSDR RSASSSTTSS
     ASQPQERCPS TRSSSFSEGR SPLEQPSSVT HFNVPSPKDS FSPASEMSSS TTSQSEDTWT
     GSQDDPQSDV NDGPEYLAIG NSGRRGRACS SASTNSTKSS SYKLFSSSSS QKVDSVSSLG
     EQGASGGGSR GLSLLRRSSF SEGQSSATQG ILKKSHVRSH SDTNVASGKL HESHDDSSGG
     RRPVSASTQS SELSTPSSLY MEYDSGQYLS SGEGMFRRPS EGQSLISYLS EQDFGSCADL
     EKENAHFSIS ESLIAAIELM KCNMMSRQLE EEEEDSDKEI QELKQKIRIR RQQIRTRHLY
     PTCQGMGSDS LVVTDSGSQF SSHGSMRLSD SGSAEDVEEY EIRDADIKRN PDSXRKSFLS
     SESISHSFLN SNSAEAVAMG LLKQFEGMQL PAASELEWLV PEHDAPQKLL PIPDSLPISP
     DDGEHADIYK LRIRVRGNLE WAPPRPQIIF NVHPAPTRKV AVAKQNYRCA GCGIRTDPDY
     IKRLRYCEYL GKYFCQCCHE NAQMVIPSRI LRKWDFSKYY VSNFSKDLLS KIWSDPLFNV
     QDINPALYRK VKSLNQVQLL RIQLFHMKNM FKTCRLAKDL LDSFDTVPGH LTEDLHLYSL
     SDLSATKKGE LVPRLTELLK AGSLHVEKCM LCQAKGFICE FCQXESDIIF PFELNKCSTC
     EECKACYHKF CFKSTRCPRC ERLQARRELL AXQSVESYVS DXEEELEQSE VVAAT
//