ID A0A0Q3TNT8_AMAAE Unreviewed; 755 AA.
AC A0A0Q3TNT8;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=Leucine-rich repeat and WD repeat-containing protein 1 {ECO:0000256|ARBA:ARBA00015536};
DE AltName: Full=Origin recognition complex-associated protein {ECO:0000256|ARBA:ARBA00033046};
GN ORFNames=AAES_73077 {ECO:0000313|EMBL:KQK82158.1};
OS Amazona aestiva (Blue-fronted Amazon parrot).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Psittaciformes; Psittacidae; Amazona.
OX NCBI_TaxID=12930 {ECO:0000313|EMBL:KQK82158.1, ECO:0000313|Proteomes:UP000051836};
RN [1] {ECO:0000313|EMBL:KQK82158.1, ECO:0000313|Proteomes:UP000051836}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FVVF132 {ECO:0000313|EMBL:KQK82158.1};
RA Gilbert D.G.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Chromosome, centromere, kinetochore
CC {ECO:0000256|ARBA:ARBA00004629}. Chromosome, telomere
CC {ECO:0000256|ARBA:ARBA00004574}. Cytoplasm, cytoskeleton, microtubule
CC organizing center, centrosome {ECO:0000256|ARBA:ARBA00004300}. Nucleus
CC {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the LRWD1 family.
CC {ECO:0000256|ARBA:ARBA00007545}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KQK82158.1}.
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DR EMBL; LMAW01001980; KQK82158.1; -; Genomic_DNA.
DR STRING; 12930.A0A0Q3TNT8; -.
DR Proteomes; UP000051836; Unassembled WGS sequence.
DR GO; GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-KW.
DR GO; GO:0000776; C:kinetochore; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR025875; Leu-rich_rpt_4.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR24370:SF10; LEUCINE-RICH REPEAT AND WD REPEAT-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR24370; OPTICIN; 1.
DR Pfam; PF12799; LRR_4; 1.
DR SMART; SM00320; WD40; 3.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS51450; LRR; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 1.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 3: Inferred from homology;
KW Centromere {ECO:0000256|ARBA:ARBA00023328};
KW Chromosome {ECO:0000256|ARBA:ARBA00022454};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW Kinetochore {ECO:0000256|ARBA:ARBA00022838};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000051836};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Telomere {ECO:0000256|ARBA:ARBA00022895};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT REPEAT 485..519
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 211..360
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 218..235
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 249..265
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 266..291
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 319..351
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 755 AA; 85457 MW; E929501612311375 CRC64;
MSKITTELLL ERAVPRSTRL RKIETLNLSK LQLKTGDLDP RLFSRLRHLQ KLDLSDNLLD
KFPNSLTLPD LRVLNCNNNK LEDVTALKQF PLLEELTYEN NVYLTLNDDY KVMFLLQNLR
LLNGKDITKX AKHVRHVNSR KLTSKVTAHW EKFFRDQLPE KYTAEQVKSI KKKFLKSVQT
NVVYGPSSLS EFTRWRVKMI AEEFLACSLG LELNSDPEPE EKMDENEEEE STESPREDAE
DKGQVTATAR KRKRNRSKTR SRKKRSKPQV APEKEAVVNP RKSRHVQDEP APQKPRPSNQ
PAKEAPPEQE AEETPKNGEQ LPKGQSNRRX RQLTGEQKSQ EQDNGVVTLN PVKSSKGKED
VSAEPLHFLQ CHSKGNSHED FKTQLWSCVF EPLLDSGARK DPIVNSSRTV ATCGGESVCL
IDCETGTVLK KYKVAAEEFF SVAWTTLTMV VSDSRKKSHN ILAAAGRRGI VKLIHVAADF
CYGEIKAHKK PIATVCFSPT RETHLFTASY DKRIALWDIG IPDSDYNFKA SQLLVLEVLS
IPLRIALVPT CPDQYLLAGC EGGCFVWNIK LDKEQKTRPF EATFQFPDED GSLTTLHRVD
GLAFLNDDVV VSKSSKPGCI YLWSWSRSFD TKGKGCQRTI AAVILAELEW STTDMSYLTL
STCPAKDYVF CGDEKGSVWM YNLSSYTTAW SSAKGKRSPF QEKRIPPAQI LQWPELRANG
EQLTEVLVNN VVSDPAFTYL VVLTSVNITA IWKKS
//
