ID A0A0Q3USG7_AMAAE Unreviewed; 1079 AA.
AC A0A0Q3USG7;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Ubiquitin-protein ligase E3B {ECO:0000313|EMBL:KQK80434.1};
GN ORFNames=AAES_93361 {ECO:0000313|EMBL:KQK80434.1};
OS Amazona aestiva (Blue-fronted Amazon parrot).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Psittaciformes; Psittacidae; Amazona.
OX NCBI_TaxID=12930 {ECO:0000313|EMBL:KQK80434.1, ECO:0000313|Proteomes:UP000051836};
RN [1] {ECO:0000313|EMBL:KQK80434.1, ECO:0000313|Proteomes:UP000051836}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FVVF132 {ECO:0000313|EMBL:KQK80434.1};
RA Gilbert D.G.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KQK80434.1}.
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DR EMBL; LMAW01002528; KQK80434.1; -; Genomic_DNA.
DR STRING; 12930.A0A0Q3USG7; -.
DR Proteomes; UP000051836; Unassembled WGS sequence.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR GO; GO:0061630; F:ubiquitin protein ligase activity; IEA:InterPro.
DR GO; GO:0000209; P:protein polyubiquitination; IEA:InterPro.
DR CDD; cd00078; HECTc; 1.
DR Gene3D; 3.30.2160.10; Hect, E3 ligase catalytic domain; 1.
DR Gene3D; 3.30.2410.10; Hect, E3 ligase catalytic domain; 1.
DR Gene3D; 3.90.1750.10; Hect, E3 ligase catalytic domains; 1.
DR InterPro; IPR044611; E3A/B/C-like.
DR InterPro; IPR000569; HECT_dom.
DR InterPro; IPR035983; Hect_E3_ubiquitin_ligase.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR PANTHER; PTHR45700:SF3; UBIQUITIN-PROTEIN LIGASE E3B; 1.
DR PANTHER; PTHR45700; UBIQUITIN-PROTEIN LIGASE E3C; 1.
DR Pfam; PF00632; HECT; 1.
DR SMART; SM00119; HECTc; 1.
DR SMART; SM00015; IQ; 1.
DR SUPFAM; SSF56204; Hect, E3 ligase catalytic domain; 1.
DR PROSITE; PS50237; HECT; 1.
DR PROSITE; PS50096; IQ; 1.
PE 4: Predicted;
KW Ligase {ECO:0000313|EMBL:KQK80434.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000051836};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786,
KW ECO:0000256|PROSITE-ProRule:PRU00104}.
FT DOMAIN 706..1079
FT /note="HECT"
FT /evidence="ECO:0000259|PROSITE:PS50237"
FT ACT_SITE 1047
FT /note="Glycyl thioester intermediate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00104"
SQ SEQUENCE 1079 AA; 123855 MW; 2D9FB0D88F20E430 CRC64;
MNMFSASQSS KAQFLDKARQ AREERRELKE RERAAVLVQA LVRRFLCRCR LQREIRREVE
DFFGTNESGS SKRSALSVFR ITRKLLFVFN PKEDRERFEK LCRCILNSMD AENEPKVWYV
SLALSKDLTL LWIKQIKDIL WFCCEFLKQL KPDILQDSXL VSLHLTMLVT FTDTSTWKIL
RGKGETLRPA MNHICANIMG HLNQKGFYSV LQILLTNGLA RSRPSLSKGS LTAVFSLALR
PVVAAQFSDN LLRSFLIHIM SVPAIMTHLA TLTPERLVVI ESHELFRKFI LFLSREAQCR
DVCVCLEGSH TLCLLGNLVF LGSLNDKVLE EETAHFVGVL IHMLSYCQKY VSQKKSNLTH
WHPVLGWFSQ TVDYGLNESM PLLTKQLQHL WGVHMIRILF CDVLSKKLLE NQEVAQLPSQ
PISPQNSLPM KNLFKRAFQK SASVRNILKP VGGKRVDSAE VQKVCSICVL YQTTLTTLTQ
IRLQILTGLT YLDDLLPKLW AFICELGPQG GLKLFLECLN NDTEESKRLL AMLMLFCDCS
RHLITILDDI EVYEEQISFK LEELVTISSF LNSFVFKMIW DGIVENARGE TLELFHSVHG
WLMVLYERDC RRRFAPEDHW LRKDLKPSVL FQELDKDKKR AQLLLQYIPH VIPHKNRVLL
FRNMVTKEKE KLGLVETSSA SPHVTHITIR RSRMLEDGYE QLRQLSQNAM KGVIRVKFVN
DLGVDEAGID QDGVFKEFLE EIIKKVFDPA LNLFKVXXRA ADADHGDERL YPSPTSYIHE
NYLQLFEFVG KMLGKAVYEG IVVDVPFASF FLSQLLGHHH SVFYSSVDEL PSLDSEFYKN
LTSIKRYDGD ISDLGLTLSY DEDVMGQLVC HELVPGGKTI PVTNENKISY IHLMAHFRMH
TQIKSQTAAL ISGFRSIIKP EWIRMFSAPX LQRLISGDNA EIDLEDLKKH TVYYGGFHGS
HRVIIWLWDI LGNDFSPEER AMFLKFVTSC SRPPLLGFAY LKPPFSIRCV EVSDDQDTGD
TLGSVLRGFF TIRKKEPGGR LPTSSTCFNL LKLPNYSKKS ILREKLRYAI SMNTGFELS
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