ID A0A0Q4RAQ7_9BACL Unreviewed; 854 AA.
AC A0A0Q4RAQ7;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE RecName: Full=Copper resistance protein CopC {ECO:0008006|Google:ProtNLM};
GN ORFNames=ASF12_32175 {ECO:0000313|EMBL:KQO08468.1};
OS Paenibacillus sp. Leaf72.
OC Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Paenibacillus.
OX NCBI_TaxID=1736234 {ECO:0000313|EMBL:KQO08468.1, ECO:0000313|Proteomes:UP000051722};
RN [1] {ECO:0000313|EMBL:KQO08468.1, ECO:0000313|Proteomes:UP000051722}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Leaf72 {ECO:0000313|EMBL:KQO08468.1,
RC ECO:0000313|Proteomes:UP000051722};
RA Gilbert D.G.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KQO08468.1, ECO:0000313|Proteomes:UP000051722}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Leaf72 {ECO:0000313|EMBL:KQO08468.1,
RC ECO:0000313|Proteomes:UP000051722};
RA Schulze-Lefert P.;
RT "Functional overlap of the Arabidopsis leaf and root microbiotas.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KQO08468.1}.
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DR EMBL; LMLV01000014; KQO08468.1; -; Genomic_DNA.
DR RefSeq; WP_056037335.1; NZ_LMLV01000014.1.
DR AlphaFoldDB; A0A0Q4RAQ7; -.
DR STRING; 1736234.ASF12_32175; -.
DR Proteomes; UP000051722; Unassembled WGS sequence.
DR GO; GO:0042597; C:periplasmic space; IEA:InterPro.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0005507; F:copper ion binding; IEA:InterPro.
DR GO; GO:0006825; P:copper ion transport; IEA:InterPro.
DR GO; GO:0046688; P:response to copper ion; IEA:InterPro.
DR Gene3D; 2.60.40.1220; -; 1.
DR InterPro; IPR032694; CopC/D.
DR InterPro; IPR007348; CopC_dom.
DR InterPro; IPR008457; Cu-R_CopD_dom.
DR InterPro; IPR014755; Cu-Rt/internalin_Ig-like.
DR InterPro; IPR014756; Ig_E-set.
DR PANTHER; PTHR34820; INNER MEMBRANE PROTEIN YEBZ; 1.
DR PANTHER; PTHR34820:SF4; INNER MEMBRANE PROTEIN YEBZ; 1.
DR Pfam; PF04234; CopC; 1.
DR Pfam; PF05425; CopD; 1.
DR SUPFAM; SSF81296; E set domains; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Copper {ECO:0000256|ARBA:ARBA00023008};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000051722};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..27
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 28..854
FT /note="Copper resistance protein CopC"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5006231982"
FT TRANSMEM 436..458
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 478..497
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 517..542
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 554..574
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 586..607
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 628..646
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 666..687
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 30..122
FT /note="CopC"
FT /evidence="ECO:0000259|Pfam:PF04234"
FT DOMAIN 624..729
FT /note="Copper resistance protein D"
FT /evidence="ECO:0000259|Pfam:PF05425"
FT REGION 129..422
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 129..268
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 293..386
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 391..407
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 854 AA; 87286 MW; 9980E02B799A565D CRC64;
MIPHKLKINL LALAALLLFM LCSPALADAH ANMERSTPLQ DAELIESPSS IRIQYTEEFD
PDLSRIVLED EAGNAIKGKL SAEKDRWLVY TIPKLSPGIY KVKWQVLSVD THVTDGSFRF
AVGVPLASTK PSDTISLDGG ASNASPSPAA TAKPSASASP SGAGSGSSGK GNDASSGAAG
QPGSGSSSSG NSTTGGKGGS SQGGGAANGS SAGGTASGGT AGSGSSSGGS NAADGTVKGG
GSSAGTGASG GKTNGGGSSS TSPSSSAGAG DGGAIGSKAN SGAIAAEGSA VSGQVGTGGN
SSATGLGEQN SSAGDGSGEA SAGSDEAEGS SENSDGKSAN GDVAESANGE QQAATGLDPS
ITATDSPAAT EGDSTSGETA QAADASHGHS MSGEHGSDVH GADSDMEMDA DGNMIGHSGD
HNAEHQTDWR TVIYTLLRVI EVIAAACMVA FLYARYVLWS RADGSAIPKL LSKRSERLLF
IGAAIALGAT GFVHIWLLAE QLSAFDMGSG STLYQKILSA TMVGRAAWLR PALAALMLLL
AYAPQRDERW VAPLKWLMAL LLTVLYPLTG HANASPLFSA AVLSHIVHIW TAAIWFGGLM
AIISATLKAS FPSVEEQQQT LHEMIKEFSR AALPIIILLA ATGIILSLQR LNVWTELASS
SYGRLVLLKT LLLVAVIGIG AYHRFALMPR LAAGLGKGAA DNSSAHPFVQ AVRIEALLAL
AAFIVAGMLS STAPPEQPVY AEPIYWHVMG DKAHMSMRIK PEEQAYQLDV WLPTGMGAPT
QIEVQAKGDS GQGEVQDIPF SFNKGGPDPY GYEGFDKYTY LSKAPVPAVG DIWDMTIVIT
DPTGEKHRYE KHIP
//
