GenomeNet

Database: UniProt
Entry: A0A0Q4XAF3_9RHIZ
LinkDB: A0A0Q4XAF3_9RHIZ
Original site: A0A0Q4XAF3_9RHIZ 
ID   A0A0Q4XAF3_9RHIZ        Unreviewed;       503 AA.
AC   A0A0Q4XAF3;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   25-OCT-2017, entry version 17.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=ASF26_13825 {ECO:0000313|EMBL:KQP03445.1};
OS   Methylobacterium sp. Leaf93.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Methylobacteriaceae; Methylobacterium.
OX   NCBI_TaxID=1736249 {ECO:0000313|EMBL:KQP03445.1, ECO:0000313|Proteomes:UP000052062};
RN   [1] {ECO:0000313|EMBL:KQP03445.1, ECO:0000313|Proteomes:UP000052062}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Leaf93 {ECO:0000313|EMBL:KQP03445.1,
RC   ECO:0000313|Proteomes:UP000052062};
RA   Millard Andrew;
RL   Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:KQP03445.1, ECO:0000313|Proteomes:UP000052062}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Leaf93 {ECO:0000313|EMBL:KQP03445.1,
RC   ECO:0000313|Proteomes:UP000052062};
RA   Vorholt J.;
RT   "Functional overlap of the Arabidopsis leaf and root microbiotas.";
RL   Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00911680}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KQP03445.1}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; LMMS01000029; KQP03445.1; -; Genomic_DNA.
DR   RefSeq; WP_056258228.1; NZ_LMMS01000029.1.
DR   EnsemblBacteria; KQP03445; KQP03445; ASF26_13825.
DR   Proteomes; UP000052062; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747950};
KW   Complete proteome {ECO:0000313|Proteomes:UP000052062};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00911664};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00747996};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00911684};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747895};
KW   Reference proteome {ECO:0000313|Proteomes:UP000052062}.
FT   DOMAIN      197    322       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      411    480       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     205    212       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   503 AA;  54448 MW;  688344A92A4DAD7D CRC64;
     MHVDGSVAGN AETGMGGAGG SDTVAAWARV KRRLRAELGE DVFASWFARL ELVEVVSGTA
     RLSVPTRFLK SWIESHYLDR VLATFRSEVE SVSLIEVGVR GAGAPPRVVS GAVKSSSPAS
     PLARLQATSN AQPSSGEMTF PAEAESSSQP RGEASGDLNG APLDNRLTFA SFVVGRSNAL
     AHAAAERVAR HDGQGALYNP LYLHAGVGLG KTHLLHGIGH AARESGRRVI YLTADRFMYG
     FVNALKTQSA LAFKEKLRAI DLLILDDVQF IQGKSIQAEF GHTINSLIDA GRQVVVASDR
     PPTELEALEE RVRSRLAGGL VVEIGMLDEQ LRMSILSARL AAVRVAHPNF EVSPTVATYV
     ARAITANGRD LEGAVNRLLA HATLTGAAVT METAETAIRD LVKNREPKRI KIEDIQKLVA
     SRYNVSRSDI LSERRTAAVV KPRQIAMYLS KVLTLRSLPE IGRRFGGRDH TTVLHAVRKI
     DKLIAEDNVL NDEVELLKRM LQD
//
DBGET integrated database retrieval system