ID   A0A0Q5RBD6_9SPHN        Unreviewed;       758 AA.
AC   A0A0Q5RBD6;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   24-JAN-2024, entry version 26.
DE   RecName: Full=JAB domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=ASG11_04440 {ECO:0000313|EMBL:KQS03591.1};
OS   Sphingomonas sp. Leaf357.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC   Sphingomonadaceae; Sphingomonas.
OX   NCBI_TaxID=1736350 {ECO:0000313|EMBL:KQS03591.1, ECO:0000313|Proteomes:UP000051080};
RN   [1] {ECO:0000313|EMBL:KQS03591.1, ECO:0000313|Proteomes:UP000051080}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Leaf357 {ECO:0000313|EMBL:KQS03591.1,
RC   ECO:0000313|Proteomes:UP000051080};
RA   Gilbert D.G.;
RL   Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:KQS03591.1, ECO:0000313|Proteomes:UP000051080}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Leaf357 {ECO:0000313|EMBL:KQS03591.1,
RC   ECO:0000313|Proteomes:UP000051080};
RA   Schulze-Lefert P.;
RT   "Functional overlap of the Arabidopsis leaf and root microbiotas.";
RL   Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KQS03591.1}.
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DR   EMBL; LMPM01000001; KQS03591.1; -; Genomic_DNA.
DR   RefSeq; WP_055775668.1; NZ_LMPM01000001.1.
DR   AlphaFoldDB; A0A0Q5RBD6; -.
DR   STRING; 1736350.ASG11_04440; -.
DR   OrthoDB; 891532at2; -.
DR   Proteomes; UP000051080; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008641; F:ubiquitin-like modifier activating enzyme activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.140.10; Cytidine Deaminase, domain 2; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR028090; JAB_dom_prok.
DR   InterPro; IPR032865; Prok-E2_A.
DR   InterPro; IPR045886; ThiF/MoeB/HesA.
DR   InterPro; IPR000594; ThiF_NAD_FAD-bd.
DR   InterPro; IPR035985; Ubiquitin-activating_enz.
DR   InterPro; IPR016135; UBQ-conjugating_enzyme/RWD.
DR   PANTHER; PTHR43267; TRNA THREONYLCARBAMOYLADENOSINE DEHYDRATASE; 1.
DR   PANTHER; PTHR43267:SF1; TRNA THREONYLCARBAMOYLADENOSINE DEHYDRATASE; 1.
DR   Pfam; PF14457; Prok-E2_A; 1.
DR   Pfam; PF14464; Prok-JAB; 1.
DR   Pfam; PF00899; ThiF; 1.
DR   SUPFAM; SSF69572; Activating enzymes of the ubiquitin-like proteins; 1.
DR   SUPFAM; SSF102712; JAB1/MPN domain; 1.
DR   SUPFAM; SSF54495; UBC-like; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Metalloprotease {ECO:0000256|ARBA:ARBA00023049};
KW   Protease {ECO:0000256|ARBA:ARBA00022670};
KW   Reference proteome {ECO:0000313|Proteomes:UP000051080};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT   DOMAIN          339..448
FT                   /note="THIF-type NAD/FAD binding fold"
FT                   /evidence="ECO:0000259|Pfam:PF00899"
FT   DOMAIN          622..723
FT                   /note="JAB"
FT                   /evidence="ECO:0000259|Pfam:PF14464"
SQ   SEQUENCE   758 AA;  82470 MW;  9D622ADE76FF7FB3 CRC64;
     MTLSRGQELA RDQLAEIADR SAGALELLRE PTLSESGLLR IYFAVATRGY RRPGGLVLRD
     RERMLLLVGT DFPFKPPTLW FSHRRFAGTP HVQWGHHVCL YQSVEAEWRP ADGMYGLIER
     IDEWLAAAGA GTLDPDDAPL HPPVAYTEAS TTVVIRADAP ATDGALWVGR ADLRTIGATR
     RDLVGWASMA DWDATPVDGT PAVAILLDRP LPSEYPTNVN DLFTSIEEAG VSFRTVWSAL
     RLSSVLVPGG EPGHVVLGAP MRRRAAGEPL RQHLTVWQLD ADALATVRAY VLNDDDAELR
     GQVAKWMVHS KVGWCTVLED RPEIVNRRDR GALVEAVAGR RVALLGCGAL GSAVAETLVR
     AGVSRLRLLD SGIVRPGILV RQRFTDDDVG AGKAARLKAR LDGLGLGCEI DVRQENLSTG
     VLAKVAELEP ELVIDATASR AVAHRLETEL DDGRLGCPLI TISVSASAEH GSVAVRMPDC
     PGGPLAVERQ AKLAALARDR TQPLVQAFWP DEPRKELFLP EPGCSSPTFT GSAADIDHHA
     GGLLNVGLRR AAELAPDAAS MDLAAPPWSA MPAGGARLLS YRLDGIETTV ERVRRYRTFT
     TKAARTGMAT EIRRVGRVKS SKCETGGLLF GEIDDSHEHI WIDSVSGPPP DSELSPERFL
     CGTAGTRALA RRRLEGSGGS SRFIGLWHTH PVSRGRPSDE DMAAMVQLLH LQPHPPRQVA
     MLIIGFAERR PDPNLYLFHR DDFRFTRIDE LPYDIGDG
//