ID   A0A0Q7AK49_9BURK        Unreviewed;       343 AA.
AC   A0A0Q7AK49;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   24-JAN-2024, entry version 22.
DE   SubName: Full=Isocitrate dehydrogenase {ECO:0000313|EMBL:KQW35892.1};
DE            EC=1.1.1.41 {ECO:0000313|EMBL:KQW35892.1};
GN   ORFNames=ASC76_14145 {ECO:0000313|EMBL:KQW35892.1};
OS   Rhizobacter sp. Root404.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales; Rhizobacter.
OX   NCBI_TaxID=1736528 {ECO:0000313|EMBL:KQW35892.1, ECO:0000313|Proteomes:UP000051611};
RN   [1] {ECO:0000313|EMBL:KQW35892.1, ECO:0000313|Proteomes:UP000051611}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Root404 {ECO:0000313|EMBL:KQW35892.1,
RC   ECO:0000313|Proteomes:UP000051611};
RA   Gilbert D.G.;
RL   Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:KQW35892.1, ECO:0000313|Proteomes:UP000051611}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Root404 {ECO:0000313|EMBL:KQW35892.1,
RC   ECO:0000313|Proteomes:UP000051611};
RA   Schulze-Lefert P.;
RT   "Functional overlap of the Arabidopsis leaf and root microbiotas.";
RL   Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the isocitrate and isopropylmalate
CC       dehydrogenases family. {ECO:0000256|ARBA:ARBA00007769}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KQW35892.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; LMDS01000005; KQW35892.1; -; Genomic_DNA.
DR   RefSeq; WP_056467489.1; NZ_LMDS01000005.1.
DR   AlphaFoldDB; A0A0Q7AK49; -.
DR   STRING; 1736528.ASC76_14145; -.
DR   OrthoDB; 5289857at2; -.
DR   Proteomes; UP000051611; Unassembled WGS sequence.
DR   GO; GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:UniProtKB-EC.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR   Gene3D; 3.40.718.10; Isopropylmalate Dehydrogenase; 1.
DR   InterPro; IPR019818; IsoCit/isopropylmalate_DH_CS.
DR   InterPro; IPR024084; IsoPropMal-DH-like_dom.
DR   PANTHER; PTHR11835; DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE; 1.
DR   PANTHER; PTHR11835:SF34; ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT ALPHA, MITOCHONDRIAL; 1.
DR   Pfam; PF00180; Iso_dh; 1.
DR   SMART; SM01329; Iso_dh; 1.
DR   SUPFAM; SSF53659; Isocitrate/Isopropylmalate dehydrogenase-like; 1.
DR   PROSITE; PS00470; IDH_IMDH; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase {ECO:0000313|EMBL:KQW35892.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000051611}.
FT   DOMAIN          4..336
FT                   /note="Isopropylmalate dehydrogenase-like"
FT                   /evidence="ECO:0000259|SMART:SM01329"
SQ   SEQUENCE   343 AA;  36549 MW;  196131D29DCCC6CB CRC64;
     MSTTIAATLI PGDGIGPEIV DATLAALDAL KAPFEWDRQI AGLGGVQTSG DPLPQATLDS
     IRRTRLALKG PLETPSGGGY RSSNVRLREE FKLYANLRPA RTLIPGGRFD NIDLVVVREN
     LEGLYIGHEH YVQIDDDPHA VAMATGINTR AGSRRLLEYA FETAVATGRK KVTIVHKANI
     MKALTGIFLE TGLELYERKY KGRFVLDTVI IDACAMKLVL NPWQFDMLVT TNLFGDILSD
     LVAGLVGGLG MAPGANIGAD AAIFEAVHGS APDIAGKGIA NPTAIMLAAA LMLDHVKRPE
     LATRLRRALD ETLNLDKVRT GDLGGTAGTA AFTKALVSRI ANG
//