ID A0A0Q7B6X9_9ACTN Unreviewed; 1937 AA.
AC A0A0Q7B6X9;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 38.
DE RecName: Full=Alpha-1,2-mannosidase {ECO:0008006|Google:ProtNLM};
GN ORFNames=ASC77_07020 {ECO:0000313|EMBL:KQW48499.1};
OS Nocardioides sp. Root1257.
OC Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC Nocardioidaceae; Nocardioides.
OX NCBI_TaxID=1736439 {ECO:0000313|EMBL:KQW48499.1, ECO:0000313|Proteomes:UP000051939};
RN [1] {ECO:0000313|EMBL:KQW48499.1, ECO:0000313|Proteomes:UP000051939}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Root1257 {ECO:0000313|EMBL:KQW48499.1,
RC ECO:0000313|Proteomes:UP000051939};
RA Gilbert D.G.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KQW48499.1, ECO:0000313|Proteomes:UP000051939}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Root1257 {ECO:0000313|EMBL:KQW48499.1,
RC ECO:0000313|Proteomes:UP000051939};
RA Schulze-Lefert P.;
RT "Functional overlap of the Arabidopsis leaf and root microbiotas.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KQW48499.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LMDV01000008; KQW48499.1; -; Genomic_DNA.
DR RefSeq; WP_056151266.1; NZ_LMDV01000008.1.
DR STRING; 1736439.ASC77_07020; -.
DR Proteomes; UP000051939; Unassembled WGS sequence.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR GO; GO:0016798; F:hydrolase activity, acting on glycosyl bonds; IEA:UniProtKB-KW.
DR GO; GO:0000272; P:polysaccharide catabolic process; IEA:UniProtKB-KW.
DR CDD; cd04084; CBM6_xylanase-like; 2.
DR CDD; cd00063; FN3; 2.
DR Gene3D; 2.70.98.10; -; 1.
DR Gene3D; 1.20.1270.90; AF1782-like; 1.
DR Gene3D; 1.20.1050.60; alpha-1,2-mannosidase; 1.
DR Gene3D; 1.20.1610.10; alpha-1,2-mannosidases domains; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 3.
DR Gene3D; 3.30.2080.10; GH92 mannosidase domain; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR008928; 6-hairpin_glycosidase_sf.
DR InterPro; IPR006584; Cellulose-bd_IV.
DR InterPro; IPR005084; CMB_fam6.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR014718; GH-type_carb-bd.
DR InterPro; IPR041371; GH92_N.
DR InterPro; IPR012939; Glyco_hydro_92.
DR InterPro; IPR013783; Ig-like_fold.
DR PANTHER; PTHR12143; PEPTIDE N-GLYCANASE PNGASE -RELATED; 1.
DR PANTHER; PTHR12143:SF39; SECRETED PROTEIN-RELATED; 1.
DR Pfam; PF03422; CBM_6; 3.
DR Pfam; PF00041; fn3; 2.
DR Pfam; PF07971; Glyco_hydro_92; 2.
DR Pfam; PF17678; Glyco_hydro_92N; 1.
DR SMART; SM00606; CBD_IV; 3.
DR SMART; SM00060; FN3; 3.
DR SUPFAM; SSF49265; Fibronectin type III; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 3.
DR SUPFAM; SSF48208; Six-hairpin glycosidases; 1.
DR PROSITE; PS51175; CBM6; 3.
DR PROSITE; PS50853; FN3; 2.
PE 4: Predicted;
KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277};
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00023295};
KW Polysaccharide degradation {ECO:0000256|ARBA:ARBA00023326};
KW Reference proteome {ECO:0000313|Proteomes:UP000051939};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..38
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 39..1937
FT /note="Alpha-1,2-mannosidase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5006302265"
FT DOMAIN 993..1134
FT /note="CBM6"
FT /evidence="ECO:0000259|PROSITE:PS51175"
FT DOMAIN 1148..1291
FT /note="CBM6"
FT /evidence="ECO:0000259|PROSITE:PS51175"
FT DOMAIN 1301..1441
FT /note="CBM6"
FT /evidence="ECO:0000259|PROSITE:PS51175"
FT DOMAIN 1582..1676
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1677..1763
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 56..88
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 650..669
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 650..667
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1937 AA; 201603 MW; C446B0118D655732 CRC64;
MPISRSRRSR TPRVIPSLVA AALAAVGLAA APAGTATAAP AATDYTQLVN PFMSTQGDNG
QNIPGAQVPH GLAKPNPMTS PGRTHSGYDY AQSSIRGFTL SNLDGVGGSG GGGDLLVVPT
YSTYTARPAT STYALPFSHT DETAEPGYYQ VGLQAPQGTI GSELTATVRT GLERFTFPQA
GKASLVLDLQ NNFTGRLSSD LTVKTLDDGR AELFGNVAGT FNGYNYKLYF DSVTSAPVAS
VKTWGDGAAF GATKHRTGTD TGAVVTFDVT AGQKVQLNTT LSPISVAQAR QDQAAELTGK
SFDDVRADAH DDWQETLGKV AVTSDATSDP DGDLEKIFYT SLYRMLATPT NATSTDGTYR
GVDGAVHRAD GYTHYDGWGT WDDFRKYSVL ATMYPDMYAD VVQSLVDIYA DDANVGNATL
SSRTMAVPTV RFERSAIVIA DAVSKGVHLD RLAQAFPALV ANSNTYSSAN QALGYIAGDP
GTTVATSYDD YALSVIAKAL GRTADATSYA ARSGNYKNVL KPAAWTAEDS TPVAVLSSRN
AAGAFANDDL EQFQAAGLYQ GTLWQFNWYP AQDMAGLISA MGGTAATQKA LSHYFGEQAP
DDGTKMLKSN ANEVDLQTPY LFNYLGQPAK TQKWVRDLYT KATWQQYIAT GGTDGNNPPS
SNGKLTPPIR TKVFKNEPLG FLPTMDDDTG AMSATFVAAA LGLYPVTAGS SQYQVGSPFF
PRVDITHDDG TSFSVVADGV SPDDYYIQDA TLDGKAYGNT WVDYDDIVGD GSFDVTMGDA
ASTWGSTSKP AFSLSTAGAD TPATATVTSD RTTVAADAEG DVDGTIRMTL NGASFAGANG
DELTGSGKVV VAGLPSGVTA TATRTSGTAL TVHVTGTLPK LARSRFAVRL TDAALAGGVA
AASVTGTGLS MRDPFAVVVT DHWRAQLRAT YDEARLVVAG NYDGSTYAAL VSARNSARTV
LADTTATDDE INNADATLSG TLDGLVLSQG GYRRLEAEKH DSWSGGADLH DEASGIGGVR
PGSWIAFNGV TFGADQVPDQ IQVRYSGASA DGYANAAVEV HLGAADGPLL AKVATPPTAS
SFGTYATATA DLTNVEALLA AAPATVYFTF TGTNPTSTDT SQHWVGNFDF MQFAESGAQA
PVDNDVVLTP EGRAEWGGDG VSVGSGTLKT ETDTGSAGSF TAIANTHNGD WVRWSGVDFS
RAPSQLSVHY INNSGRVAPD ANIDVYLDSR SGTKLVNVPL PATGSSWSSD GTATVDLPSG
VTGKHDVYIV MHGTYTAERP YVGNYGNLTF VVPDAPKSDG LKVEFESRTA WAGPELKTES
FSWNDGTTGT DVGGTHEGDV LEYDGLVFDD TATSLSVHYV NNSSRCGNNS RIDVYLDAKA
GSPLLTVPLP VTGSGWSSAG TTKVTLPTAI SGTHKVILVL RTDVPDANHP FVSNLDSFTF
NYGVDKAALQ DRYDLDEPKL TDGDRYVGVD FRLFSDAMTA AKEVLADETA IGSDVSTALR
TLQLADGQLA PRAQRSLVAA VRDADEVVPA RYTQATVATL TSAVSDSKAM LSAATATDEE
YAAQAGTLEA AIDGLELKAS SAPDAPQAVS ATTSGRSITV SWAAPAYDGN SAITGYTVQL
TGVTPTTVDA ATTSYTFTDL PRGRQYRASV KATNALGSSA ASEYAVDLPI ASVKPEVPAK
PGIAAAGQAV TVSWTAPDDG GSTITGYTVQ LSDGTEAEVA GTETSHTFSG LAAGDYSAYV
AARNVNGRSS FSPVSATATV LPAPTVSGVT ATAPSWSQVK VAWTTTGSTR FVLEVQLSRA
GKVIATRQAW SDASDVVFTG LDAATAYQAT VAPVGGSVAA TAAVRTPARP KVASHAVQVK
GVAKVGKRLA VNLHAGSWSA GTRFSYVWLA NGKVVGRAAT LRLTPGLKGK KVAVRVTGAH
GDWTPSTVTS KAVKVKR
//
