ID A0A0Q7QAY6_9ACTN Unreviewed; 628 AA.
AC A0A0Q7QAY6;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=DNA methylase N-4/N-6 domain-containing protein {ECO:0000259|Pfam:PF01555};
GN ORFNames=ASD11_04940 {ECO:0000313|EMBL:KQY60642.1};
OS Aeromicrobium sp. Root495.
OC Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC Nocardioidaceae; Aeromicrobium.
OX NCBI_TaxID=1736550 {ECO:0000313|EMBL:KQY60642.1, ECO:0000313|Proteomes:UP000051970};
RN [1] {ECO:0000313|EMBL:KQY60642.1, ECO:0000313|Proteomes:UP000051970}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Root495 {ECO:0000313|EMBL:KQY60642.1,
RC ECO:0000313|Proteomes:UP000051970};
RA Gilbert D.G.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KQY60642.1, ECO:0000313|Proteomes:UP000051970}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Root495 {ECO:0000313|EMBL:KQY60642.1,
RC ECO:0000313|Proteomes:UP000051970};
RA Schulze-Lefert P.;
RT "Functional overlap of the Arabidopsis leaf and root microbiotas.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the N(4)/N(6)-methyltransferase family.
CC {ECO:0000256|ARBA:ARBA00006594}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KQY60642.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LMFJ01000001; KQY60642.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0Q7QAY6; -.
DR STRING; 1736550.ASD11_04940; -.
DR Proteomes; UP000051970; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0008170; F:N-methyltransferase activity; IEA:InterPro.
DR GO; GO:0006306; P:DNA methylation; IEA:InterPro.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR002941; DNA_methylase_N4/N6.
DR InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR InterPro; IPR002295; N4/N6-MTase_EcoPI_Mod-like.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR Pfam; PF01555; N6_N4_Mtase; 1.
DR PIRSF; PIRSF015855; TypeIII_Mtase_mKpnI; 1.
DR PRINTS; PR00506; D21N6MTFRASE.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00092; N6_MTASE; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Reference proteome {ECO:0000313|Proteomes:UP000051970};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 121..435
FT /note="DNA methylase N-4/N-6"
FT /evidence="ECO:0000259|Pfam:PF01555"
FT REGION 279..299
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 628 AA; 69809 MW; FC23F2FA7E024334 CRC64;
MDKLKMHSPD LTQHNIDQIA ELFPAVVTET LDADGSPVRA VDFDALRQEL SDHVVEGPQE
RYQLDWPGKR AAAFAANAPI AKTLRPVRAE SVDFDTTKNL FIEGDNLEAL KLLQESYIGK
VKLIYIDPPY NTGNDFVYED DFAESSADYL ARSGQTSETG DRLVANTEAN GRFHSDWLSM
MYPRLRLARN LLTSNGVIVI SIDDSEVSRL TSLCDEVFGA DNHVETLVWK RRYGGGAKER
HFASIHEYLV VYARDLSQLE ELFVDLTDEQ IERYFKSTDQ NSTTRGPYRT QPLEPAASMG
DRPNLRFPII APDGSELWPK RQWLWSRERV AEASERGELE FRQGTNGWQV SIKQYLNDET
GARRKTKATS IVEGIYGQLG SAELKKLFSG KDLFPYAKPS ALVQRLVDIF TVRDSLVLDF
FAGSGSTAHG VMAQGALDRL PRRWIVVQLG EAVDAKSEAG KAGYRTIAEL SRERIRLAGA
QVGVGAGMLA EDLDVGFRSL RVDSTNMADV LASPDGTEQD ELLGAVDSVK QDRGAEDLLF
QVLLDWGLDL SLPIVREQIE GYEVFAVDDD GVMACFADSV TEAVVQAIAK RHPLRAVFKD
AGFASDAARI NAEQIFREVS PETEVRAI
//
