ID A0A0Q8LPY8_9MICO Unreviewed; 766 AA.
AC A0A0Q8LPY8;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=SSD domain-containing protein {ECO:0000259|PROSITE:PS50156};
GN ORFNames=ASD93_02540 {ECO:0000313|EMBL:KRB38834.1};
OS Microbacterium sp. Root180.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Microbacterium.
OX NCBI_TaxID=1736483 {ECO:0000313|EMBL:KRB38834.1, ECO:0000313|Proteomes:UP000050802};
RN [1] {ECO:0000313|EMBL:KRB38834.1, ECO:0000313|Proteomes:UP000050802}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Root180 {ECO:0000313|EMBL:KRB38834.1,
RC ECO:0000313|Proteomes:UP000050802};
RA Gilbert D.G.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KRB38834.1, ECO:0000313|Proteomes:UP000050802}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Root180 {ECO:0000313|EMBL:KRB38834.1,
RC ECO:0000313|Proteomes:UP000050802};
RA Schulze-Lefert P.;
RT "Functional overlap of the Arabidopsis leaf and root microbiotas.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the resistance-nodulation-cell division (RND)
CC (TC 2.A.6) family. MmpL subfamily. {ECO:0000256|ARBA:ARBA00010157}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRB38834.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LMHS01000001; KRB38834.1; -; Genomic_DNA.
DR RefSeq; WP_056118233.1; NZ_LMHS01000001.1.
DR AlphaFoldDB; A0A0Q8LPY8; -.
DR STRING; 1736483.ASD93_02540; -.
DR OrthoDB; 2365435at2; -.
DR Proteomes; UP000050802; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR004869; MMPL_dom.
DR InterPro; IPR000731; SSD.
DR PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR PANTHER; PTHR33406:SF6; MEMBRANE PROTEIN SCO0839-RELATED; 1.
DR Pfam; PF03176; MMPL; 2.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR PROSITE; PS50156; SSD; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000050802};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..39
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 169..196
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 203..225
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 237..258
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 279..300
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 312..335
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 376..395
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 556..573
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 580..601
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 613..633
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 654..674
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 680..701
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 583..711
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
FT REGION 733..766
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 744..766
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 766 AA; 80217 MW; 76582A4B306584F0 CRC64;
MATPHHARST PTRWLRIGIP ALLVLVWLVV GSIGGPYFGK VDQVSSNDRS SFLPESADAT
QVNERLPDFL GDDSIPAVVV VTGDGELTED QLADVQTLAD DIAEVPGVLE GVSPAIVSED
GEAAQLFVPV DASGEVAEIV DEIRTLVDDD LASPLEGWVT GPAGFTADLV AGFLGIDGLL
LAVALIAVFV ILVIVYRSPL LPVLVLLTSV FALCVALLTV WWLAYAGIFV LNGQVQGILF
ILVIGAATDY ALLYVARFRE AVADGDRRWD ATVRAWRGSF EPILASGGTV IAGLLCLLLS
DLATNRALGP IASIGIAFSV LSALTFLPAL LALFGRAAFW PFIPKAPIAT IPDDLTQPVK
GLWPRQARFI ARHARAVWVI CTVVLLVGAL GITQLKADGV PSSDLVLGQS EARDGQAVLA
EHFPAGSGSP VYVIVPEEEL AGAVEVLDGS DGIESVAVAS EDSPTGQASV ELESGEPVFT
AVGAPGTPAP TPTVSAGDVL VIGTLTDAAD SVAAEDTVRE LRTDLDEALG AGTAIVGGET
ATDIDSNDTS IRDRTVIIPV ILAVILLILM LLLRSILAPV VLIATVILSF ATALGVAALV
FDGVFAFPGA DPAVPLYGFV FLVALGVDYN IFLMSRVREE SLVHGTRRGI LRGLVATGGV
ITSAGLVLAA TFAALGVIPI LFLAQIAFIV AFGVLLDTFV VRSLLVPALS YDIGRAIWWP
SRLWRDGVEK TADAAPRGPA AEDSSELVAE DGHPLTREEY RRTLDS
//
